Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

36 transcription factors

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 227 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 170 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 108 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 247 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 269 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 403 bp overlap

ChIP DE DE-GATA4-2 421 bp overlap

ChIP foregut GSE117136.GATA4.foregut 246 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 392 bp overlap

ChIP DE DE-GATA6-2 382 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 487 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 482 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 487 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 372 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 470 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 427 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 415 bp overlap

ChIP foregut GSE117136.GATA6.foregut 319 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 282 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 251 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 164 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000BNR.HDAC2.WA01 166 bp overlap

JUN 2 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 322 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 472 bp overlap

KLF4 1 dataset

ChIP hiPSC GSE56567.KLF4.hiPSC 147 bp overlap

MED1 1 dataset

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 252 bp overlap

NANOG 4 datasets

ChIP WA01 ERP004238.NANOG.WA01 227 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 436 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 224 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 264 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 192 bp overlap

PAXIP1 1 dataset

ChIP HepG2 ENCFF526NOJ 69 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 326 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 225 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 329 bp overlap

RXRA 1 dataset

ChIP WA01 ENCSR000BJW.RXRA.WA01 126 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 389 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 417 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 475 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 487 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 454 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 477 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 487 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 362 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 152 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 288 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 283 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 487 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 235 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 231 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 294 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 367 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 262 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 227 bp overlap

ZBTB33 3 datasets

ChIP HepG2 ENCFF778UKV 115 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 102 bp overlap

ChIP K562 ENCFF875HLX 77 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 340 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 287 bp overlap

ZNF460 1 dataset

ChIP HepG2 ENCFF007NNM 267 bp overlap

ZNF700 1 dataset

ChIP K562 ENCFF657OXY 275 bp overlap

Gene	Dist. to TSS	Distance	Link type
ZNF564	20.2 kb	Distal	Multiome
ZNF490	39.1 kb	Distal	Multiome
ZNF791	39.2 kb	Distal	Multiome
MAN2B1	85.7 kb	Distal	Multiome
ZNF709	86.9 kb	Distal	Multiome
WDR83OS	97.7 kb	Distal	Multiome
WDR83	98.1 kb	Distal	Multiome
DHPS	109.7 kb	Distal	Multiome
FBXW9	124.9 kb	Distal	Multiome
ZNF443	130.7 kb	Distal	Multiome
TNPO2	152.2 kb	Distal	Multiome
TRIR	163.0 kb	Distal	Multiome
GET3	165.5 kb	Distal	Multiome
HOOK2	203.9 kb	Distal	Multiome
PRDX2	230.1 kb	Distal	Multiome
MAST1	262.3 kb	Distal	Multiome

Genome Browser