chr18 : 4,813,533 4,814,481
948 bp 95 TFs 1 linked gene
This 948 bp open chromatin element is linked to ENSG00000266268 and is bound by 95 transcription factors.
Linked Genes
1 gene
Gene Expression Dist. to TSS Distance Link type
ENSG00000266268 190.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:4,808,533 – 4,819,481
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
95 transcription factors
Source
Cell type
ATF4 4 datasets
Motif DE_12h DE_12h-ATF4_MA0833.3 10 bp overlap
Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap
Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap
Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap
BARX1 1 dataset
Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap
BCL6B 1 dataset
Motif DE_60h DE_60h-BCL6B_MA0731.1 17 bp overlap
BSX 1 dataset
Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap
CEBPG 4 datasets
Motif DE_12h DE_12h-CEBPG_MA1636.2 10 bp overlap
Motif DE_36h DE_36h-CEBPG_MA1636.2 10 bp overlap
Motif DE_48h DE_48h-CEBPG_MA1636.2 10 bp overlap
Motif DE_60h DE_60h-CEBPG_MA1636.2 10 bp overlap
CTCF 7 datasets
Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
Motif DE_36h DE_36h-CTCF_MA1930.2 33 bp overlap
Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap
Motif DE_60h DE_60h-CTCF_MA1930.2 33 bp overlap
Motif DE_72h DE_72h-CTCF_MA1930.2 33 bp overlap
ChIP endodermal cell ENCFF471YCZ 461 bp overlap
DLX1 1 dataset
Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap
DUX4 1 dataset
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Dlx2 1 dataset
Motif DE_60h DE_60h-Dlx2_MA0885.3 8 bp overlap
Dlx3 1 dataset
Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap
Dlx5 1 dataset
Motif DE_60h DE_60h-Dlx5_MA1476.3 8 bp overlap
E2F6 4 datasets
Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap
Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 352 bp overlap
FIGLA 10 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 551 bp overlap
ChIP DE DE-FOXA2-2 430 bp overlap
Foxq1 2 datasets
Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap
Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap
GATA1::TAL1 5 datasets
Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_24h DE_24h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 4 datasets
Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 581 bp overlap
ChIP DE DE-GATA4-2 572 bp overlap
Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 568 bp overlap
ChIP DE DE-GATA6-2 516 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 560 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 674 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 593 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 473 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 675 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 561 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 450 bp overlap
GBX2 1 dataset
Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap
Gata3 4 datasets
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HESX1 1 dataset
Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap
HOXA6 1 dataset
Motif DE_60h DE_60h-HOXA6_MA1497.2 7 bp overlap
HOXA7 1 dataset
Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap
HOXB6 1 dataset
Motif DE_60h DE_60h-HOXB6_MA1500.2 7 bp overlap
HOXB7 1 dataset
Motif DE_60h DE_60h-HOXB7_MA1501.2 7 bp overlap
HOXB8 1 dataset
Motif DE_60h DE_60h-HOXB8_MA1502.2 7 bp overlap
HOXC12 5 datasets
Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap
Motif DE_24h DE_24h-HOXC12_MA0906.2 10 bp overlap
Motif DE_36h DE_36h-HOXC12_MA0906.2 10 bp overlap
Motif DE_48h DE_48h-HOXC12_MA0906.2 10 bp overlap
Motif DE_60h DE_60h-HOXC12_MA0906.2 10 bp overlap
HOXD11 5 datasets
Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap
Motif DE_24h DE_24h-HOXD11_MA0908.2 9 bp overlap
Motif DE_36h DE_36h-HOXD11_MA0908.2 9 bp overlap
Motif DE_48h DE_48h-HOXD11_MA0908.2 9 bp overlap
Motif DE_60h DE_60h-HOXD11_MA0908.2 9 bp overlap
HOXD8 1 dataset
Motif DE_60h DE_60h-HOXD8_MA0910.3 7 bp overlap
Hmx2 1 dataset
Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap
Hoxd13 5 datasets
Motif DE_12h DE_12h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_24h DE_24h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_36h DE_36h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_60h DE_60h-Hoxd13_MA0909.4 7 bp overlap
IRF7 1 dataset
Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap
IRF8 1 dataset
Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap
ISL2 4 datasets
Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 287 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 257 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 263 bp overlap
LBX2 1 dataset
Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap
LHX2 1 dataset
Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap
LIN54 2 datasets
Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
MSX1 1 dataset
Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap
Msx3 1 dataset
Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 614 bp overlap
NR1I3 1 dataset
Motif DE_60h DE_60h-NR1I3_MA1534.2 8 bp overlap
NR6A1 1 dataset
Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap
Nobox 1 dataset
Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap
Nr2e3 4 datasets
Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_36h DE_36h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap
PHOX2A 1 dataset
Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
POU4F2 1 dataset
Motif DE_60h DE_60h-POU4F2_MA0683.2 15 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 527 bp overlap
PROP1 1 dataset
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
RAX 1 dataset
Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap
RBPJ 6 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
SMAD2 4 datasets
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 144 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 504 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 626 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 577 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 548 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 600 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 501 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 523 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 473 bp overlap
SOX15 5 datasets
Motif DE_12h DE_12h-SOX15_MA1152.2 7 bp overlap
Motif DE_24h DE_24h-SOX15_MA1152.2 7 bp overlap
Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap
Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 246 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 453 bp overlap
SPIB 1 dataset
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
STAT1 2 datasets
Motif DE_36h DE_36h-STAT1_MA0137.4 9 bp overlap
Motif DE_60h DE_60h-STAT1_MA0137.4 9 bp overlap
STAT3 2 datasets
Motif DE_36h DE_36h-STAT3_MA0144.3 9 bp overlap
Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap
Spi1 1 dataset
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Stat4 2 datasets
Motif DE_36h DE_36h-Stat4_MA0518.2 10 bp overlap
Motif DE_60h DE_60h-Stat4_MA0518.2 10 bp overlap
Stat5b 2 datasets
Motif DE_36h DE_36h-Stat5b_MA1625.2 9 bp overlap
Motif DE_60h DE_60h-Stat5b_MA1625.2 9 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 305 bp overlap
TAL1::TCF3 6 datasets
Motif DE_12h DE_12h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_24h DE_24h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_36h DE_36h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_72h DE_72h-TAL1TCF3_MA0091.2 10 bp overlap
TBX18 4 datasets
Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TCF7L1 1 dataset
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 4 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 4 datasets
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tbx6 4 datasets
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
Wt1 4 datasets
Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap
Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap
ZBTB32 3 datasets
Motif DE_36h DE_36h-ZBTB32_MA1580.1 10 bp overlap
Motif DE_48h DE_48h-ZBTB32_MA1580.1 10 bp overlap
Motif DE_60h DE_60h-ZBTB32_MA1580.1 10 bp overlap
ZBTB6 5 datasets
Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_36h DE_36h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
ZBTB7C 6 datasets
Motif DE_12h DE_12h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_24h DE_24h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_36h DE_36h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_48h DE_48h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_72h DE_72h-ZBTB7C_MA0695.2 8 bp overlap
ZEB1 10 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF282 1 dataset
Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap
ZNF341 5 datasets
Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap
Motif DE_24h DE_24h-ZNF341_MA1655.2 8 bp overlap
Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
ZNF35 1 dataset
Motif DE_60h DE_60h-ZNF35_MA2333.1 7 bp overlap
ZNF354C 6 datasets
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_24h DE_24h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap
ZNF652 4 datasets
Motif DE_12h DE_12h-ZNF652_MA1657.2 9 bp overlap
Motif DE_36h DE_36h-ZNF652_MA1657.2 9 bp overlap
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
ZNF75A 4 datasets
Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
ZNF75D 4 datasets
Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_36h DE_36h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap
ZNF85 3 datasets
Motif DE_36h DE_36h-ZNF85_MA1720.2 12 bp overlap
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
ZSCAN4 4 datasets
Motif DE_12h DE_12h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_36h DE_36h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_48h DE_48h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap