chr16 : 72,162,164 – 72,162,652

488 bp 61 TFs 1 linked gene

This 488 bp open chromatin element is linked to PMFBP1 and is bound by 61 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PMFBP1		9.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 334 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 258 bp overlap

ASXL3 2 datasets

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 208 bp overlap

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 236 bp overlap

BAP1 1 dataset

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 406 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap

BRD1 1 dataset

ChIP RKO GSE47190.BRD1.RKO 151 bp overlap

BRD4 1 dataset

ChIP NCI-H2171 GSE101821.BRD4.NCI-H2171 373 bp overlap

CEBPA 5 datasets

ChIP THP-1_1-25D_24h GSE124032.CEBPA.THP-1_1-25D_24h 265 bp overlap

ChIP THP-1_1-25D_8h GSE124032.CEBPA.THP-1_1-25D_8h 246 bp overlap

ChIP THP-1_EtOH_24h GSE124032.CEBPA.THP-1_EtOH_24h 236 bp overlap

ChIP THP-1_EtOH_2h GSE124032.CEBPA.THP-1_EtOH_2h 220 bp overlap

ChIP THP-1_EtOH_8h GSE124032.CEBPA.THP-1_EtOH_8h 293 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 263 bp overlap

ELF3 1 dataset

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 320 bp overlap

ELK1::SREBF2 1 dataset

Motif DE_12h DE_12h-ELK1SREBF2_MA1933.2 15 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 466 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FLI1 1 dataset

ChIP NB4 GSE23730.FLI1.NB4 166 bp overlap

GATA6 5 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 459 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 488 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 488 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 488 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 488 bp overlap

HNF4A 2 datasets

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

ChIP IM95 GSE114018.HNF4A.IM95 132 bp overlap

Hic1 1 dataset

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

Hmga1 1 dataset

Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap

JMJD1C 1 dataset

ChIP THP-1 GSE63484.JMJD1C.THP-1 222 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 390 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 488 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 483 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 488 bp overlap

KLF4 1 dataset

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 208 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 213 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

MYC 1 dataset

ChIP BJ_INDUCED GSE36570.MYC.BJ_INDUCED 106 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 482 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 488 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 200 bp overlap

ChIP hESC GSE18292.NANOG.hESC 271 bp overlap

ChIP hESC GSE20650.NANOG.hESC 151 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 126 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 119 bp overlap

Nr2F6 1 dataset

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

PAX7 1 dataset

ChIP H9_DOX GSE98976.PAX7.H9_DOX 380 bp overlap

PDX1 1 dataset

ChIP islet ERP001456.PDX1.islet 92 bp overlap

PHF19 1 dataset

ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 191 bp overlap

POU4F1 1 dataset

Motif DE_12h DE_12h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap

POU5F1 4 datasets

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 202 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 488 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 343 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 271 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 393 bp overlap

RAD21 3 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 373 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 488 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 418 bp overlap

RARA 2 datasets

Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap

RELA 1 dataset

ChIP KB_IL GSE52469.RELA.KB_IL 111 bp overlap

RUNX1 1 dataset

ChIP NB4 GSE81992.RUNX1.NB4 346 bp overlap

Rarb 1 dataset

Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 157 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 83 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 122 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 488 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 488 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 488 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 488 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 488 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 280 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 388 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 332 bp overlap

SMARCC1 3 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 295 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 488 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 375 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 327 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 259 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 345 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 240 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 264 bp overlap

TP53 1 dataset

ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 269 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap