chr12 : 105,459,868 105,460,332
464 bp 58 TFs 4 linked genes
This 464 bp open chromatin element is linked to 4 target genes and is bound by 58 transcription factors.
Linked Genes
4 genes
Link type
Gene Expression Dist. to TSS Distance Link type
C12orf75 129.4 kb Distal Multiome
APPL2 224.0 kb Distal Multiome
NUAK1 678.9 kb Distal Multiome+HiCAR
TCP11L2 842.7 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:105,454,868 – 105,465,332
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
58 transcription factors
Source
Cell type
BCL6B 1 dataset
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
DPF2 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.DPF2.BIN-67_lentivirus-SMARCA4 249 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 251 bp overlap
EP300 1 dataset
ChIP tibial nerve ENCFF346AYA 189 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 412 bp overlap
ChIP DE DE-FOXA2-2 397 bp overlap
GATA2 1 dataset
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 464 bp overlap
ChIP DE DE-GATA4-2 464 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 464 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 464 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 392 bp overlap
GATA6 15 datasets
ChIP DE DE-GATA6-1 464 bp overlap
ChIP DE DE-GATA6-2 464 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 387 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 464 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 442 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 464 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 464 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 464 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 464 bp overlap
ChIP foregut GSE117136.GATA6.foregut 464 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 464 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 379 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 435 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 265 bp overlap
Gata3 1 dataset
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HSF1 1 dataset
Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap
HSF2 1 dataset
Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap
HSF4 1 dataset
Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap
ISL2 1 dataset
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 439 bp overlap
KMT2C 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.KMT2C.BIN-67_lentivirus-SMARCA4 346 bp overlap
KMT2D 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.KMT2D.BIN-67_lentivirus-SMARCA4 267 bp overlap
MED1 1 dataset
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 301 bp overlap
MEIS1 1 dataset
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
NR2C1 1 dataset
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR5A1 1 dataset
Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap
Nr1H2 1 dataset
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
PKNOX2 1 dataset
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
POLR2A 1 dataset
ChIP esophagus muscularis mucosa ENCFF759BBR 391 bp overlap
RBPJ 2 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
RELA 13 datasets
ChIP 786-O GSE86092.RELA.786-O 83 bp overlap
ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 141 bp overlap
ChIP GM12891 ENCSR000EAI.RELA.GM12891 121 bp overlap
ChIP HAEC GSE89970.RELA.HAEC 59 bp overlap
ChIP HAEC_IL1b_4h GSE89970.RELA.HAEC_IL1b_4h 76 bp overlap
ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 189 bp overlap
ChIP HUVEC-C_TNF-30min GSE121890.RELA.HUVEC-C_TNF-30min 51 bp overlap
ChIP HUVEC-C_TNF-60min GSE121890.RELA.HUVEC-C_TNF-60min 110 bp overlap
ChIP HUVEC-C_TNF_30M GSE34500.RELA.HUVEC-C_TNF_30M 51 bp overlap
ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 69 bp overlap
ChIP HeLa-B2_TA_TNFA GSE24518.RELA.HeLa-B2_TA_TNFA 99 bp overlap
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 277 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 258 bp overlap
RORA 1 dataset
Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap
RORB 1 dataset
Motif DE_72h DE_72h-RORB_MA1150.2 10 bp overlap
RORC 1 dataset
Motif DE_72h DE_72h-RORC_MA1151.2 10 bp overlap
SMAD2-3 3 datasets
ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 102 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 464 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 330 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 464 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 464 bp overlap
SMARCA4 2 datasets
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 252 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 199 bp overlap
SMARCC1 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4 226 bp overlap
SMC1 1 dataset
ChIP HCAEC GSE101921.SMC1.HCAEC 223 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 407 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 438 bp overlap
SS18 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 464 bp overlap
STAT3 1 dataset
Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap
Stat4 1 dataset
Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap
TAL1 1 dataset
ChIP PRIMA5 GSE33850.TAL1.PRIMA5 184 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 290 bp overlap
TGIF1 1 dataset
Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap
TGIF2 1 dataset
Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap
TGIF2LX 1 dataset
Motif DE_72h DE_72h-TGIF2LX_MA1571.1 12 bp overlap
TGIF2LY 1 dataset
Motif DE_72h DE_72h-TGIF2LY_MA1572.1 12 bp overlap
TRPS1 1 dataset
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZNF257 1 dataset
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF281 1 dataset
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF324 1 dataset
Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap
ZNF416 1 dataset
Motif DE_48h DE_48h-ZNF416_MA1979.2 10 bp overlap
ZNF582 1 dataset
Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap
ZNF770 2 datasets
ChIP HEK293 GSE76494.ZNF770.HEK293 241 bp overlap
ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 247 bp overlap
Zfp809 1 dataset
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap