chr6 : 167,893,383 – 167,893,698
315 bp 64 TFs 1 linked gene
This 315 bp open chromatin element is linked to AFDN and is bound by 64 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
AFDN at TSS At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:167,888,383 – 167,898,698
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
64 transcription factors
Source
Cell type
ARID1A 2 datasets
ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 236 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.ARID1A.endometrial-epithelial-cells_KO 193 bp overlap
ATF3 4 datasets
ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 152 bp overlap
ChIP HCT-116_DMSO GSE74355.ATF3.HCT-116_DMSO 114 bp overlap
ChIP K-562 ENCSR028UIU.ATF3.K-562 263 bp overlap
ChIP WA01 ENCSR000BKC.ATF3.WA01 143 bp overlap
BCL11A 2 datasets
ChIP H1 ENCFF833IPY 145 bp overlap
ChIP WA01 ENCSR000BIP.BCL11A.WA01 139 bp overlap
BRD4 3 datasets
ChIP MDA-MB-231_JQ1_MGSK2801 GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801 279 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801_rDNA GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801_rDNA 279 bp overlap
ChIP SUM159PT_30nMbortezomib_8h GSE87418.BRD4.SUM159PT_30nMbortezomib_8h 246 bp overlap
BRD9 1 dataset
ChIP MDA-MB-231_MGSK2801 GSE116879.BRD9.MDA-MB-231_MGSK2801 188 bp overlap
CBX3 1 dataset
ChIP HCT116 ENCFF947BOL 281 bp overlap
CREBBP 1 dataset
ChIP keratinocyte_KLF3i GSE140991.CREBBP.keratinocyte_KLF3i 233 bp overlap
CTCF 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 180 bp overlap
ELF3 1 dataset
ChIP PDAC GSE64557.ELF3.PDAC 286 bp overlap
ESR1 1 dataset
ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 193 bp overlap
FOS 7 datasets
ChIP IMR-90 ENCFF179EDA 242 bp overlap
ChIP IMR-90 ENCSR124AIG.FOS.IMR-90 208 bp overlap
ChIP K-562 ENCSR000DKB.FOS.K-562 170 bp overlap
ChIP MCF-10A ENCSR000DON.FOS.MCF-10A 199 bp overlap
ChIP MCF-7 ENCFF282FWZ 173 bp overlap
ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 241 bp overlap
ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 244 bp overlap
FOSL1 8 datasets
ChIP HCT-116 ENCSR000BTE.FOSL1.HCT-116 144 bp overlap
ChIP HCT116 ENCFF540ZXN 299 bp overlap
ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 315 bp overlap
ChIP K-562 ENCSR000BMV.FOSL1.K-562 127 bp overlap
ChIP K562 ENCFF455MKD 315 bp overlap
ChIP K562 ENCFF455MKD 271 bp overlap
ChIP K562 ENCFF728OTE 178 bp overlap
ChIP WA01 ENCSR000BNS.FOSL1.WA01 110 bp overlap
FOSL2 9 datasets
ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 145 bp overlap
ChIP HepG2 ENCFF548CXY 245 bp overlap
ChIP HepG2 ENCFF796NIA 204 bp overlap
ChIP LPS141 GSE111253.FOSL2.LPS141 188 bp overlap
ChIP MCF-7 ENCSR000BUI.FOSL2.MCF-7 128 bp overlap
ChIP NPC_K755R-pos GSE122631.FOSL2.NPC_K755R-pos 277 bp overlap
ChIP NPC_R1159Q GSE122631.FOSL2.NPC_R1159Q 181 bp overlap
ChIP SK-N-SH ENCFF127ZDW 223 bp overlap
ChIP SK-N-SH ENCSR000BVB.FOSL2.SK-N-SH 165 bp overlap
FOXA1 5 datasets
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 254 bp overlap
ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 266 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 266 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 279 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 315 bp overlap
FOXA2 4 datasets
ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 300 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 308 bp overlap
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 301 bp overlap
ChIP DE DE-FOXA2-1 273 bp overlap
FOXL2 1 dataset
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 174 bp overlap
GRHL2 2 datasets
ChIP HBE GSE46194.GRHL2.HBE 176 bp overlap
ChIP OVCA429 GSE71018.GRHL2.OVCA429 185 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000BNR.HDAC2.WA01 120 bp overlap
HIF1A 1 dataset
ChIP PC-3_hypoxia_siCtrl GSE106305.HIF1A.PC-3_hypoxia_siCtrl 236 bp overlap
HMBOX1 1 dataset
ChIP K-562 ENCSR757IIU.HMBOX1.K-562 134 bp overlap
HNF1B 1 dataset
ChIP PDAC GSE64557.HNF1B.PDAC 315 bp overlap
IRF2 1 dataset
ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 125 bp overlap
JUN 14 datasets
ChIP 786-O GSE86092.JUN.786-O 189 bp overlap
ChIP DE_D1 S08-DE-d1-JUN-exp1 315 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 315 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 315 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 315 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 315 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 315 bp overlap
ChIP H1 ENCFF621PNP 204 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 315 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 315 bp overlap
ChIP K-562 ENCSR000FAH.JUN.K-562 144 bp overlap
ChIP Karpas-299 GSE151413.JUN.Karpas-299 315 bp overlap
ChIP MCF10A-Er-Src_EtOH GSE115597.JUN.MCF10A-Er-Src_EtOH 149 bp overlap
ChIP WA01 ENCSR000ECA.JUN.WA01 135 bp overlap
JUNB 3 datasets
ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 315 bp overlap
ChIP HAEC GSE89970.JUNB.HAEC 140 bp overlap
ChIP MCF10A-Er-Src_EtOH GSE115597.JUNB.MCF10A-Er-Src_EtOH 171 bp overlap
JUND 11 datasets
ChIP Calu-3 GSE85401.JUND.Calu-3 145 bp overlap
ChIP H1 ENCFF010YXS 245 bp overlap
ChIP H1 ENCFF468JZD 176 bp overlap
ChIP HCT-116 ENCSR000BSA.JUND.HCT-116 158 bp overlap
ChIP HCT116 ENCFF748ZQX 264 bp overlap
ChIP HepG2 ENCFF869OPW 235 bp overlap
ChIP K-562 ENCSR000EGN.JUND.K-562 150 bp overlap
ChIP SK-N-SH ENCFF971JKN 220 bp overlap
ChIP SK-N-SH ENCSR000EIB.JUND.SK-N-SH 149 bp overlap
ChIP WA01 ENCSR000EBZ.JUND.WA01 187 bp overlap
ChIP WA01 ENCSR000BKP.JUND.WA01 182 bp overlap
KLF6 1 dataset
ChIP PDAC GSE64557.KLF6.PDAC 300 bp overlap
MYOD1 2 datasets
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 204 bp overlap
ChIP myoblast GSE50413.MYOD1.myoblast 179 bp overlap
NANOG 5 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 315 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 152 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 315 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 201 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 315 bp overlap
NFKB1 1 dataset
ChIP MCF10A-Er-Src_TAM GSE115597.NFKB1.MCF10A-Er-Src_TAM 288 bp overlap
NR3C1 1 dataset
ChIP SUM159PT GSE152203.NR3C1.SUM159PT 228 bp overlap
OSR2 2 datasets
ChIP HEK293 ENCFF875BDB 315 bp overlap
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 227 bp overlap
PDX1 1 dataset
ChIP islet ERP001456.PDX1.islet 173 bp overlap
PGR 1 dataset
ChIP breast_tumor_Male_30 GSE104399.PGR.breast_tumor_Male_30 151 bp overlap
POLR2A 1 dataset
ChIP neural cell ENCFF604SPB 211 bp overlap
POU5F1 2 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 126 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 315 bp overlap
PRDM1 1 dataset
ChIP HEK293 ENCFF302TBP 277 bp overlap
PROX1 1 dataset
ChIP SW480 GSE60390.PROX1.SW480 93 bp overlap
RAD21 1 dataset
ChIP IMR-90 ENCSR000EFJ.RAD21.IMR-90 118 bp overlap
RBPJ 1 dataset
ChIP SCC_4h GSE156486.RBPJ.SCC_4h 289 bp overlap
RELA 1 dataset
ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 209 bp overlap
REXO4 1 dataset
ChIP HepG2 ENCFF947WAO 240 bp overlap
RFX5 4 datasets
ChIP Hep-G2 ENCSR000EEA.RFX5.Hep-G2 149 bp overlap
ChIP HepG2 ENCFF065UQI 242 bp overlap
ChIP MCF-7 ENCFF983ILY 253 bp overlap
ChIP MCF-7 ENCSR924TVL.RFX5.MCF-7 227 bp overlap
RUNX1 1 dataset
ChIP 697 GSE138031.RUNX1.697 315 bp overlap
SCRT1 2 datasets
ChIP HEK293 ENCFF513YVP 283 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 194 bp overlap
SCRT2 1 dataset
ChIP HEK293 ENCFF711QQB 315 bp overlap
SMAD3 5 datasets
ChIP BG03 GSE21614.SMAD3.BG03 172 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 224 bp overlap
ChIP HMLE_Doxycicline_TGFb GSE104760.SMAD3.HMLE_Doxycicline_TGFb 194 bp overlap
ChIP NCI-H441 GSE51509.SMAD3.NCI-H441 131 bp overlap
ChIP NCI-H441_SIITTF1 GSE51509.SMAD3.NCI-H441_SIITTF1 224 bp overlap
SMAD3-HIF1A 1 dataset
ChIP PC-3_hypoxia GSE106305.SMAD3-HIF1A.PC-3_hypoxia 174 bp overlap
SMARCA4 13 datasets
ChIP A-549_AG15677 GSE132290.SMARCA4.A-549_AG15677 102 bp overlap
ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 163 bp overlap
ChIP A-549_AG15720 GSE132290.SMARCA4.A-549_AG15720 159 bp overlap
ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 115 bp overlap
ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 105 bp overlap
ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 134 bp overlap
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 315 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 192 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 166 bp overlap
ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 207 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 315 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 226 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 283 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 261 bp overlap
SMARCC1 3 datasets
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4 182 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 315 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 266 bp overlap
SMC3 2 datasets
ChIP IMR-90 ENCSR000HPG.SMC3.IMR-90 75 bp overlap
ChIP IMR-90 ENCSR000HPG.SMC3.IMR-90 172 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 148 bp overlap
SS18 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 315 bp overlap
STAT3 4 datasets
ChIP MCF-10A ENCSR000DOZ.STAT3.MCF-10A 162 bp overlap
ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 151 bp overlap
ChIP MCF10A-Er-Src_EtOH GSE115597.STAT3.MCF10A-Er-Src_EtOH 151 bp overlap
ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 157 bp overlap
TAF1 2 datasets
ChIP H1 ENCFF478SZO 315 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 143 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 160 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 224 bp overlap
TP53 2 datasets
ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 168 bp overlap
ChIP SW480_shp53_16h_TNF-a GSE115985.TP53.SW480_shp53_16h_TNF-a 95 bp overlap
TP63 15 datasets
ChIP BxPC-3 GSE115461.TP63.BxPC-3 227 bp overlap
ChIP HaCaT_LacZ_TGFB GSE60814.TP63.HaCaT_LacZ_TGFB 152 bp overlap
ChIP HaCaT_caRAS_TGFB GSE60814.TP63.HaCaT_caRAS_TGFB 154 bp overlap
ChIP HaCaT_dnRAS_TGFB GSE60814.TP63.HaCaT_dnRAS_TGFB 122 bp overlap
ChIP JHU-029 GSE88859.TP63.JHU-029 166 bp overlap
ChIP MCF-10A_Nutlin3A GSE111009.TP63.MCF-10A_Nutlin3A 157 bp overlap
ChIP SUIT-2 GSE115461.TP63.SUIT-2 277 bp overlap
ChIP TT GSE46837.TP63.TT 151 bp overlap
ChIP keratinocyte GSE56674.TP63.keratinocyte 128 bp overlap
ChIP keratinocyte_CISP GSE56674.TP63.keratinocyte_CISP 169 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 180 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 193 bp overlap
ChIP keratinocyte_D4 GSE59824.TP63.keratinocyte_D4 177 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 166 bp overlap
ChIP keratinocyte_epidermal GSE67382.TP63.keratinocyte_epidermal 89 bp overlap
ZEB2 1 dataset
ChIP K-562 ENCSR004GKA.ZEB2.K-562 260 bp overlap
ZFP64 1 dataset
ChIP HEK293 GSE76494.ZFP64.HEK293 157 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 237 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 223 bp overlap
ZNF766 1 dataset
ChIP HEK293T GSE78099.ZNF766.HEK293T 115 bp overlap
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