chr5:151,496,053–151,496,694

chr5 : 151,496,053 – 151,496,694

641 bp 64 TFs 6 linked genes

This 641 bp open chromatin element is linked to 6 target genes and is bound by 64 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC36A1		48.7 kb	Distal	Multiome
SLC36A2		148.7 kb	Distal	Multiome
SPARC		190.6 kb	Distal	Multiome
GM2A		243.1 kb	Distal	Multiome
ATOX1		262.3 kb	Distal	Multiome
G3BP1		275.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 641 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 641 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 504 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 256 bp overlap

Arid3a 3 datasets

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap

Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 187 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 193 bp overlap

BRCA1 2 datasets

ChIP H1 ENCFF288NOI 280 bp overlap

ChIP WA01 ENCSR000EBX.BRCA1.WA01 210 bp overlap

CHD2 4 datasets

ChIP H1 ENCFF991MKH 194 bp overlap

ChIP K-562 ENCSR000EHD.CHD2.K-562 197 bp overlap

ChIP K562 ENCFF857WME 286 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 265 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 198 bp overlap

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 109 bp overlap

DUX4 3 datasets

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

Motif DE_24h DE_24h-DUX4_MA0468.1 11 bp overlap

Motif ES_0h ES_0h-DUX4_MA0468.1 11 bp overlap

DUXA 3 datasets

Motif DE_12h DE_12h-DUXA_MA0884.2 13 bp overlap

Motif DE_24h DE_24h-DUXA_MA0884.2 13 bp overlap

Motif ES_0h ES_0h-DUXA_MA0884.2 13 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_24h DE_24h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 604 bp overlap

ChIP DE DE-FOXA2-2 575 bp overlap

FOXD2 1 dataset

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 487 bp overlap

ChIP DE DE-GATA4-2 484 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 493 bp overlap

ChIP DE DE-GATA6-2 523 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 554 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 641 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 564 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 616 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 478 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 479 bp overlap

GTF2F1 1 dataset

ChIP H1 ENCFF399TGL 345 bp overlap

Gmeb1 2 datasets

Motif DE_12h DE_12h-Gmeb1_MA0615.2 6 bp overlap

Motif ES_0h ES_0h-Gmeb1_MA0615.2 6 bp overlap

Hand1::Tcf3 2 datasets

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

ChIP SK-N-SH ENCFF285GEQ 485 bp overlap

Irf1 3 datasets

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

Motif DE_24h DE_24h-Irf1_MA0050.4 11 bp overlap

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 396 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 437 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 283 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 450 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 406 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 356 bp overlap

KDM4A 2 datasets

ChIP WA01 ENCSR000AVC.KDM4A.WA01 216 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 189 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 329 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 207 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 314 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 284 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

PHOX2A 3 datasets

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

Motif DE_24h DE_24h-PHOX2A_MA0713.1 11 bp overlap

Motif ES_0h ES_0h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 3 datasets

Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap

Motif DE_24h DE_24h-PHOX2B_MA0681.3 12 bp overlap

Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap

POLR2A 4 datasets

ChIP GM23338 ENCFF450WCS 245 bp overlap

ChIP H1 ENCFF566JSR 408 bp overlap

ChIP H1 ENCFF770YBQ 438 bp overlap

ChIP H1 ENCFF833NJP 263 bp overlap

POU2F1::SOX2 3 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 6 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 562 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 282 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 152 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 299 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 261 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 338 bp overlap

PROP1 3 datasets

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

Motif DE_24h DE_24h-PROP1_MA0715.1 11 bp overlap

Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap

Pou5f1::Sox2 3 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 135 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 238 bp overlap

REST 8 datasets

ChIP H1 ENCFF203SWY 392 bp overlap

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP WA01 ENCSR663WAR.REST.WA01 228 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 108 bp overlap

ChIP hiPSC_IA12 GSE106870.REST.hiPSC_IA12 204 bp overlap

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 200 bp overlap

ChIP hiPSC_IIA11 GSE106870.REST.hiPSC_IIA11 165 bp overlap

ChIP hiPSC_IID12 GSE106870.REST.hiPSC_IID12 196 bp overlap

SMAD2 2 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 320 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 451 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 623 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 641 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 586 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 641 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 283 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 501 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 475 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 258 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 228 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

SNAI2 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR106GVM.SNAI2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 268 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 272 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 446 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 261 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 250 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 485 bp overlap

ChIP H1 ENCFF859IIO 214 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 367 bp overlap

ChIP hESC GSE122298.TBP.hESC 377 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 169 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 312 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 197 bp overlap

TEAD1 4 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD3 3 datasets

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 450 bp overlap

ChIP H1 ENCFF778PAX 150 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 223 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 205 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 139 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 139 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 280 bp overlap

Motif DE_12h DE_12h-YY2_MA0748.3 7 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 515 bp overlap

ChIP K562 ENCFF427SDV 419 bp overlap

ChIP K562 ENCFF875HLX 327 bp overlap

ZIM3 3 datasets

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

Motif DE_24h DE_24h-ZIM3_MA1709.2 11 bp overlap

Motif ES_0h ES_0h-ZIM3_MA1709.2 11 bp overlap

ZNF354A 3 datasets

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

Motif DE_24h DE_24h-ZNF354A_MA1978.2 20 bp overlap

Motif ES_0h ES_0h-ZNF354A_MA1978.2 20 bp overlap

ZNF416 2 datasets

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

Motif ES_0h ES_0h-ZNF416_MA1979.2 10 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 190 bp overlap

ZNF766 3 datasets

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

Motif DE_24h DE_24h-ZNF766_MA2098.1 9 bp overlap

Motif ES_0h ES_0h-ZNF766_MA2098.1 9 bp overlap

ZNF8 2 datasets

Motif DE_12h DE_12h-ZNF8_MA1718.1 20 bp overlap

Motif ES_0h ES_0h-ZNF8_MA1718.1 20 bp overlap