chr5 : 146,919,400 – 146,919,666

266 bp 69 TFs 1 linked gene

This 266 bp open chromatin element is linked to PPP2R2B-IT1 and is bound by 69 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PPP2R2B-IT1		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

69 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 141 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BCL11B 1 dataset

ChIP thymus_CD34pos GSE84677.BCL11B.thymus_CD34pos 67 bp overlap

BHLHE22 3 datasets

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap

Bach1::Mafk 2 datasets

Motif DE_12h DE_12h-Bach1Mafk_MA0591.2 12 bp overlap

Motif ES_0h ES_0h-Bach1Mafk_MA0591.2 12 bp overlap

Bhlha15 1 dataset

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 266 bp overlap

CTCF 1 dataset

ChIP primary-glioblastoma_G523 GSE121601.CTCF.primary-glioblastoma_G523 112 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 266 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 201 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 241 bp overlap

ERF::FOXO1 1 dataset

Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap

EZH2 2 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 266 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 151 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-2 266 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 266 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap

GLI3 2 datasets

Motif DE_12h DE_12h-GLI3_MA1491.3 15 bp overlap

Motif ES_0h ES_0h-GLI3_MA1491.3 15 bp overlap

Gli1 2 datasets

Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap

Motif ES_0h ES_0h-Gli1_MA1990.2 10 bp overlap

Gli2 2 datasets

Motif DE_12h DE_12h-Gli2_MA0734.4 9 bp overlap

Motif ES_0h ES_0h-Gli2_MA0734.4 9 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

IRF3 1 dataset

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

IRF4 1 dataset

Motif DE_12h DE_12h-IRF4_MA1419.2 14 bp overlap

IRF7 1 dataset

Motif DE_12h DE_12h-IRF7_MA0772.2 13 bp overlap

IRF8 1 dataset

Motif DE_12h DE_12h-IRF8_MA0652.2 13 bp overlap

IRF9 1 dataset

Motif DE_12h DE_12h-IRF9_MA0653.1 15 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

MAFK 2 datasets

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

Motif ES_0h ES_0h-MAFK_MA0496.4 10 bp overlap

MAX 1 dataset

ChIP WA01 ENCSR000EUP.MAX.WA01 260 bp overlap

MGA::EVX1 1 dataset

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

MSC 1 dataset

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

MYF5 1 dataset

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

MYF6 1 dataset

Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

Mafg 2 datasets

Motif DE_12h DE_12h-Mafg_MA0659.4 12 bp overlap

Motif ES_0h ES_0h-Mafg_MA0659.4 12 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 223 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 160 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 170 bp overlap

Neurod2 3 datasets

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap

Olig2 3 datasets

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap

Ptf1A 3 datasets

Motif DE_12h DE_12h-Ptf1A_MA1618.2 9 bp overlap

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RAD21 2 datasets

ChIP neural ENCSR198ZYJ.RAD21.neural 200 bp overlap

ChIP neural cell ENCFF564MOT 266 bp overlap

RARA 1 dataset

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 229 bp overlap

RBPJ 2 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 253 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 266 bp overlap

SAP30 2 datasets

ChIP H1 ENCFF149IOE 266 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 239 bp overlap

SIN3A 7 datasets

ChIP H1 ENCFF042ZSL 266 bp overlap

ChIP H1 ENCFF896IJG 258 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 231 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 192 bp overlap

ChIP hiPSC_IA12 GSE106870.SIN3A.hiPSC_IA12 133 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 266 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 192 bp overlap

SIX1 1 dataset

Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap

SIX2 1 dataset

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

SMARCA4 5 datasets

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 264 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 266 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 266 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 175 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 219 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 177 bp overlap

SOX2 6 datasets

ChIP HNSC GSE69479.SOX2.HNSC 266 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 171 bp overlap

ChIP hESC GSE18292.SOX2.hESC 94 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 266 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 207 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 266 bp overlap

SP1 2 datasets

ChIP H1 ENCFF263FUH 266 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 239 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Stat2 1 dataset

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

TAL1::TCF3 1 dataset

Motif DE_12h DE_12h-TAL1TCF3_MA0091.2 10 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 181 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 244 bp overlap

TEAD1 1 dataset

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 180 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 221 bp overlap

TFAP4 1 dataset

Motif DE_12h DE_12h-TFAP4_MA0691.1 10 bp overlap

TFCP2 1 dataset

Motif DE_12h DE_12h-TFCP2_MA1968.2 9 bp overlap

Tcf12 3 datasets

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

Twist2 3 datasets

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZBTB7B 2 datasets

Motif DE_12h DE_12h-ZBTB7B_MA0694.2 10 bp overlap

Motif ES_0h ES_0h-ZBTB7B_MA0694.2 10 bp overlap

ZBTB7C 2 datasets

Motif DE_12h DE_12h-ZBTB7C_MA0695.2 8 bp overlap

Motif ES_0h ES_0h-ZBTB7C_MA0695.2 8 bp overlap

ZIM3 1 dataset

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF708 1 dataset

Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap

ZNF75D 1 dataset

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

ZNF90 1 dataset

ChIP HEK293T GSE78099.ZNF90.HEK293T 266 bp overlap