chr5 : 83,465,707 – 83,466,172

465 bp 63 TFs 1 linked gene

This 465 bp open chromatin element is linked to VCAN and is bound by 63 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
VCAN		5.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

AR 1 dataset

ChIP LNCaP GSE43720.AR.LNCaP 74 bp overlap

BRD4 1 dataset

ChIP 402-91 GSE111253.BRD4.402-91 153 bp overlap

CASZ1 1 dataset

ChIP rhabdomyosarcoma_Ctrl GSE126142.CASZ1.rhabdomyosarcoma_Ctrl 236 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 151 bp overlap

ERG 1 dataset

ChIP aortic-endothelial-cell_D24 GSE139377.ERG.aortic-endothelial-cell_D24 155 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV5FOXI1_MA1946.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 296 bp overlap

ChIP DE DE-FOXA2-2 296 bp overlap

FOXD2 1 dataset

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap

Foxj2 1 dataset

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Foxq1 1 dataset

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

GATA2 1 dataset

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 172 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-1 237 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 269 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 186 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 280 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 213 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 259 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 321 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 243 bp overlap

GRHL2 1 dataset

Motif DE_12h DE_12h-GRHL2_MA1105.3 8 bp overlap

HMBOX1 1 dataset

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

HOXD12::ELK1 1 dataset

Motif DE_12h DE_12h-HOXD12ELK1_MA1958.2 13 bp overlap

HSF2 1 dataset

Motif DE_12h DE_12h-HSF2_MA0770.1 13 bp overlap

JUN 2 datasets

ChIP ESC S34-ESC-d0-JUN-exp2 279 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 329 bp overlap

KDM5B 1 dataset

ChIP HCC2157 GSE46055.KDM5B.HCC2157 174 bp overlap

LIN54 1 dataset

Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap

Lhx3 1 dataset

Motif DE_12h DE_12h-Lhx3_MA0135.2 12 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MTF2 1 dataset

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 213 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 365 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 192 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 311 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 194 bp overlap

NCOA2 1 dataset

ChIP MCF-7 ERP000901.NCOA2.MCF-7 133 bp overlap

NR1H4::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H4RXRA_MA1146.2 13 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1538.1 15 bp overlap

NR2F6 1 dataset

Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap

NR4A2::RXRA 1 dataset

Motif DE_12h DE_12h-NR4A2RXRA_MA1147.2 13 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 206 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 3 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 465 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 218 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 289 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 162 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 186 bp overlap

SPI1 1 dataset

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 189 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TP63 1 dataset

ChIP foreskin GSE126390.TP63.foreskin 164 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 151 bp overlap

ZBTB1 1 dataset

ChIP Jurkat_ZBTB1-KO_Asp-deprivation_cDNA GSE145783.ZBTB1.Jurkat_ZBTB1-KO_Asp-deprivation_cDNA 154 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZKSCAN5 2 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF184 1 dataset

Motif DE_12h DE_12h-ZNF184_MA2120.1 13 bp overlap

ZNF257 2 datasets

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF274 1 dataset

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF37A 1 dataset

ChIP HEK293 GSE76494.ZNF37A.HEK293 127 bp overlap

ZNF530 1 dataset

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap