chr4 : 16,236,282 – 16,236,915

633 bp 74 TFs 2 linked genes

This 633 bp open chromatin element is linked to TAPT1-AS1 and TAPT1 and is bound by 74 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TAPT1-AS1		9.6 kb	Proximal	Proximity
TAPT1		9.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

AFF1 1 dataset

ChIP L826 GSE83671.AFF1.L826 210 bp overlap

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 352 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 263 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 295 bp overlap

CEBPA 1 dataset

ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 98 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 355 bp overlap

DMRTA2 1 dataset

Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap

DUX4 1 dataset

ChIP WA01 GSE94322.DUX4.WA01 331 bp overlap

ELK1::SREBF2 1 dataset

Motif DE_36h DE_36h-ELK1SREBF2_MA1933.2 15 bp overlap

EMSY 1 dataset

ChIP K562 ENCFF511ZZZ 247 bp overlap

EOMES 2 datasets

Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 555 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 299 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_36h DE_36h-ETV5FOXO1_MA1947.2 10 bp overlap

EZH2 1 dataset

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 76 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 395 bp overlap

ChIP DE DE-FOXA2-2 304 bp overlap

FOXH1 1 dataset

Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 600 bp overlap

ChIP DE DE-GATA4-2 523 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 540 bp overlap

ChIP DE DE-GATA6-2 450 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 570 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 549 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 498 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 526 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 546 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 594 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 383 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR711VWL.HDAC1.K-562 350 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 205 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR563YDA.HDGF.K-562 237 bp overlap

Hic1 1 dataset

Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap

IRF4 1 dataset

ChIP NCI-H929 GSE56857.IRF4.NCI-H929 85 bp overlap

Isl1 1 dataset

Motif DE_36h DE_36h-Isl1_MA1608.2 7 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 386 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 528 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 375 bp overlap

KLF4 1 dataset

Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap

KMT2A 4 datasets

ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 478 bp overlap

ChIP L826 GSE83671.KMT2A.L826 203 bp overlap

ChIP L826 GSE83671.KMT2A.L826 212 bp overlap

ChIP SEM GSE83671.KMT2A.SEM 543 bp overlap

MAFF 1 dataset

ChIP K562 ENCFF071YKK 203 bp overlap

MAFG 2 datasets

ChIP K-562 ENCSR818DQV.MAFG.K-562 268 bp overlap

ChIP K562 ENCFF455EEO 329 bp overlap

MGA::EVX1 1 dataset

Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap

MLLT1 1 dataset

ChIP K-562 ENCSR107GRP.MLLT1.K-562 282 bp overlap

MXI1 1 dataset

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 181 bp overlap

NFATC3 1 dataset

Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap

NFE2 4 datasets

ChIP K-562 ENCSR552YGL.NFE2.K-562 245 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 230 bp overlap

ChIP K562 ENCFF047YKA 293 bp overlap

ChIP K562 ENCFF163BSI 217 bp overlap

NKX6-3 1 dataset

Motif DE_36h DE_36h-NKX6-3_MA1530.2 8 bp overlap

NR1H4::RXRA 1 dataset

Motif DE_36h DE_36h-NR1H4RXRA_MA1146.2 13 bp overlap

NR4A2::RXRA 1 dataset

Motif DE_36h DE_36h-NR4A2RXRA_MA1147.2 13 bp overlap

Nfatc1 1 dataset

Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 247 bp overlap

RAD21 1 dataset

ChIP LoVo_PHASEM GSE51290.RAD21.LoVo_PHASEM 74 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 198 bp overlap

RNF2 1 dataset

ChIP K-562 ENCSR820GND.RNF2.K-562 310 bp overlap

Rhox11 1 dataset

Motif DE_36h DE_36h-Rhox11_MA0629.2 9 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 350 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 375 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 332 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 300 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 351 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 408 bp overlap

SMARCA4 4 datasets

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 362 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 229 bp overlap

ChIP K562 ENCFF316MCJ 379 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 395 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 310 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S10-DE-d1-BAF155-exp1 399 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 363 bp overlap

SP5 1 dataset

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

Spi1 1 dataset

Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 544 bp overlap

TBR1 1 dataset

Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap

TBX2 1 dataset

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap

TBX3 1 dataset

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

TEAD1 1 dataset

Motif DE_36h DE_36h-TEAD1_MA0090.4 9 bp overlap

Thap11 1 dataset

Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap

Wt1 1 dataset

Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap

YBX1 1 dataset

ChIP K562 ENCFF051NKX 277 bp overlap

ZEB2 2 datasets

ChIP K-562 ENCSR322CFO.ZEB2.K-562 500 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 336 bp overlap

ZIC1 2 datasets

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 291 bp overlap

ZNF416 1 dataset

Motif DE_36h DE_36h-ZNF416_MA1979.2 10 bp overlap

ZNF652 1 dataset

Motif DE_36h DE_36h-ZNF652_MA1657.2 9 bp overlap

ZNF684 1 dataset

Motif DE_36h DE_36h-ZNF684_MA1600.2 14 bp overlap

Zic1::Zic2 1 dataset

Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap