chr3 : 177,230,597 – 177,231,187
590 bp 61 TFs 1 linked gene
This 590 bp open chromatin element is linked to TBL1XR1 and is bound by 61 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TBL1XR1 33.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:177,225,597 – 177,236,187
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
61 transcription factors
Source
Cell type
AR 1 dataset
ChIP VCaP GSE148358.AR.VCaP 153 bp overlap
CDK8 1 dataset
ChIP monocyte_IFNg-LPS GSE120943.CDK8.monocyte_IFNg-LPS 132 bp overlap
CHD4 1 dataset
ChIP 501-mel GSE134848.CHD4.501-mel 147 bp overlap
CREBBP 1 dataset
ChIP MCF-7 ERP000901.CREBBP.MCF-7 183 bp overlap
CTBP2 1 dataset
ChIP MCF-7 GSE107013.CTBP2.MCF-7 178 bp overlap
CTCF 1 dataset
ChIP GSC23 GSE139416.CTCF.GSC23 233 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF346MCV 230 bp overlap
Crx 2 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
DPRX 2 datasets
Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Dmbx1 1 dataset
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
EBF1 2 datasets
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
ESR1 9 datasets
ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 240 bp overlap
ChIP MCF-7_IL1b-ICI GSE67295.ESR1.MCF-7_IL1b-ICI 155 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 109 bp overlap
ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 240 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 289 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 149 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 183 bp overlap
ChIP MCF-7_shFbxo_E2_4OHT GSE119702.ESR1.MCF-7_shFbxo_E2_4OHT 201 bp overlap
ChIP MCF-7_shFbxo_OHT GSE119702.ESR1.MCF-7_shFbxo_OHT 201 bp overlap
Ebf4 2 datasets
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
FLI1 1 dataset
ChIP ME-1 GSE46044.FLI1.ME-1 254 bp overlap
FOXA1 3 datasets
ChIP MCF-7 GSE72249.FOXA1.MCF-7 198 bp overlap
ChIP MCF-7_DEX GSE72249.FOXA1.MCF-7_DEX 221 bp overlap
ChIP MCF-7_E2 GSE72249.FOXA1.MCF-7_E2 218 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 437 bp overlap
ChIP DE DE-FOXA2-2 446 bp overlap
FOXD3 2 datasets
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
GATA2 5 datasets
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 226 bp overlap
ChIP HepG2 ENCFF905PYM 371 bp overlap
ChIP SKH1 GSE87283.GATA2.SKH1 175 bp overlap
ChIP VCaP GSE125236.GATA2.VCaP 199 bp overlap
ChIP VCaP_JQ1 GSE125236.GATA2.VCaP_JQ1 150 bp overlap
GATA3 11 datasets
ChIP MCF-7 ENCFF352QVM 481 bp overlap
ChIP MCF-7 ENCFF437NQS 371 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 269 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 199 bp overlap
ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 231 bp overlap
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 180 bp overlap
ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 168 bp overlap
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 113 bp overlap
ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 285 bp overlap
ChIP MCF-7_ICI GSE81510.GATA3.MCF-7_ICI 139 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 166 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 523 bp overlap
ChIP DE DE-GATA4-2 549 bp overlap
ChIP foregut GSE117136.GATA4.foregut 512 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 437 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 453 bp overlap
ChIP DE DE-GATA6-2 590 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 295 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 318 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 499 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 392 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 422 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 431 bp overlap
ChIP foregut GSE117136.GATA6.foregut 489 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 339 bp overlap
GFI1 3 datasets
Motif DE_36h DE_36h-GFI1_MA0038.3 11 bp overlap
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap
GSC 2 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Hmx2 2 datasets
Motif DE_36h DE_36h-Hmx2_MA0897.2 15 bp overlap
Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 275 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 110 bp overlap
MAFF 2 datasets
Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
MED1 1 dataset
ChIP MCF-7_SHCTR GSE60270.MED1.MCF-7_SHCTR 156 bp overlap
Mafb 2 datasets
Motif DE_36h DE_36h-Mafb_MA0117.3 11 bp overlap
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
NFYA 2 datasets
Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
NFYC 2 datasets
Motif DE_36h DE_36h-NFYC_MA1644.2 7 bp overlap
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
NR2F2 1 dataset
ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 125 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 127 bp overlap
NRL 2 datasets
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 503 bp overlap
OTX1 2 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
PITX1 2 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
PITX3 2 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
RHOXF1 2 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
RXRA::VDR 1 dataset
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
SIX1 1 dataset
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
SIX2 1 dataset
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 499 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 294 bp overlap
SMARCA4 3 datasets
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 291 bp overlap
ChIP 501-mel_SHMITF GSE61965.SMARCA4.501-mel_SHMITF 119 bp overlap
ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 83 bp overlap
SMARCE1 1 dataset
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 221 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 315 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 590 bp overlap
Six4 1 dataset
Motif DE_48h DE_48h-Six4_MA2001.2 7 bp overlap
TEAD4 1 dataset
ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 230 bp overlap
TOP2A 1 dataset
ChIP KG-1_etoposide GSE114048.TOP2A.KG-1_etoposide 101 bp overlap
TRIM28 1 dataset
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 439 bp overlap
ZNF136 2 datasets
Motif DE_36h DE_36h-ZNF136_MA1588.1 15 bp overlap
Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap
ZNF16 2 datasets
Motif DE_36h DE_36h-ZNF16_MA1654.2 21 bp overlap
Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap
ZNF189 2 datasets
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
ZNF24 8 datasets
ChIP K-562 ENCSR695EQB.ZNF24.K-562 277 bp overlap
ChIP K-562 ENCSR099NCH.ZNF24.K-562 344 bp overlap
ChIP K-562 ENCSR385AHH.ZNF24.K-562 171 bp overlap
ChIP K-562 ENCSR117WTM.ZNF24.K-562 179 bp overlap
ChIP K562 ENCFF615YYW 176 bp overlap
ChIP K562 ENCFF781QQQ 208 bp overlap
ChIP K562 ENCFF877JCX 160 bp overlap
ChIP MCF-7 ENCSR503VTG.ZNF24.MCF-7 156 bp overlap
ZNF331 2 datasets
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
ZNF460 2 datasets
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
ZNF574 1 dataset
Motif DE_48h DE_48h-ZNF574_MA1982.2 14 bp overlap
ZSCAN31 2 datasets
Motif DE_36h DE_36h-ZSCAN31_MA1722.2 18 bp overlap
Motif DE_48h DE_48h-ZSCAN31_MA1722.2 18 bp overlap
Huangfu Lab · Publications · Resources · Contact