chr1 : 37,186,281 – 37,186,777
496 bp 76 TFs 1 linked gene
This 496 bp open chromatin element is linked to GRIK3 and is bound by 76 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GRIK3 152.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:37,181,281 – 37,191,777
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP NGP GSE134626.ARID1A.NGP 360 bp overlap
ASCL1 1 dataset
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 143 bp overlap
BCL11A 1 dataset
ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 71 bp overlap
BHLHE22 2 datasets
Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
BRD4 4 datasets
ChIP DND41_E GSE54379.BRD4.DND41_E 310 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 318 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 496 bp overlap
ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 368 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 273 bp overlap
EP300 2 datasets
ChIP SK-N-SH ENCFF829RWA 377 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 292 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 291 bp overlap
FEZF2 1 dataset
Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap
FIGLA 3 datasets
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FLI1 1 dataset
ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 195 bp overlap
FOS 1 dataset
ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 187 bp overlap
FOSL1 1 dataset
ChIP BT-549 GSE112961.FOSL1.BT-549 145 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 496 bp overlap
ChIP DE DE-FOXA2-2 496 bp overlap
GABPA 1 dataset
ChIP VCaP GSE49091.GABPA.VCaP 194 bp overlap
GATA1 3 datasets
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 55 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 145 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap
GATA2 10 datasets
Motif DE_24h DE_24h-GATA2_MA0036.4 7 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
ChIP SH-SY5Y ENCFF485YIB 405 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 496 bp overlap
ChIP SK-N-SH ENCFF764OZD 338 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 473 bp overlap
ChIP endothelial cell of umbilical vein ENCFF148NLK 382 bp overlap
ChIP endothelial_umbilical-vein ENCSR000EVW.GATA2.endothelial_umbilical-vein 429 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 268 bp overlap
GATA3 7 datasets
ChIP BE2C GSE65664.GATA3.BE2C 490 bp overlap
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 334 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 322 bp overlap
ChIP NGP GSE65664.GATA3.NGP 154 bp overlap
ChIP SH-SY5Y ENCFF475HYF 462 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 341 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 476 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 496 bp overlap
ChIP DE DE-GATA4-2 496 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 418 bp overlap
GATA5 1 dataset
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 496 bp overlap
ChIP DE DE-GATA6-2 496 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 496 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 496 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 496 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 496 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 496 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 496 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 444 bp overlap
ChIP foregut GSE117136.GATA6.foregut 410 bp overlap
Gata3 4 datasets
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 496 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 255 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 496 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 410 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 451 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 294 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 479 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 479 bp overlap
ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 134 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 479 bp overlap
KDM1A 1 dataset
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 254 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 167 bp overlap
MAFK 2 datasets
Motif DE_24h DE_24h-MAFK_MA0496.4 10 bp overlap
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
MAX 1 dataset
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 200 bp overlap
MAZ 1 dataset
Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap
MXI1 1 dataset
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
MYC 1 dataset
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 181 bp overlap
MYCN 5 datasets
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 331 bp overlap
ChIP Kelly GSE94822.MYCN.Kelly 199 bp overlap
ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 185 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 212 bp overlap
ChIP SK-N-BE2-C GSE94822.MYCN.SK-N-BE2-C 337 bp overlap
MYOG 2 datasets
Motif DE_24h DE_24h-MYOG_MA0500.3 8 bp overlap
Motif DE_48h DE_48h-MYOG_MA0500.3 8 bp overlap
Mafg 2 datasets
Motif DE_24h DE_24h-Mafg_MA0659.4 12 bp overlap
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
NFIB 3 datasets
Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap
Motif DE_36h DE_36h-NFIB_MA1643.2 17 bp overlap
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
NFIC 3 datasets
Motif DE_24h DE_24h-NFIC_MA1527.2 15 bp overlap
Motif DE_36h DE_36h-NFIC_MA1527.2 15 bp overlap
Motif DE_48h DE_48h-NFIC_MA1527.2 15 bp overlap
NFIC::TLX1 3 datasets
Motif DE_24h DE_24h-NFICTLX1_MA0119.1 14 bp overlap
Motif DE_36h DE_36h-NFICTLX1_MA0119.1 14 bp overlap
Motif DE_48h DE_48h-NFICTLX1_MA0119.1 14 bp overlap
NFIX 3 datasets
Motif DE_24h DE_24h-NFIX_MA1528.2 14 bp overlap
Motif DE_36h DE_36h-NFIX_MA1528.2 14 bp overlap
Motif DE_48h DE_48h-NFIX_MA1528.2 14 bp overlap
NHLH1 2 datasets
Motif DE_24h DE_24h-NHLH1_MA0048.3 9 bp overlap
Motif DE_48h DE_48h-NHLH1_MA0048.3 9 bp overlap
NHLH2 2 datasets
Motif DE_24h DE_24h-NHLH2_MA1529.2 16 bp overlap
Motif DE_48h DE_48h-NHLH2_MA1529.2 16 bp overlap
NR1D1 3 datasets
Motif DE_24h DE_24h-NR1D1_MA1531.2 14 bp overlap
Motif DE_36h DE_36h-NR1D1_MA1531.2 14 bp overlap
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
Neurod2 2 datasets
Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Olig2 2 datasets
Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 340 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 247 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 292 bp overlap
RCOR1 2 datasets
ChIP SK-N-SH ENCFF518EXB 319 bp overlap
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 326 bp overlap
RELA 1 dataset
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 269 bp overlap
SMAD2 3 datasets
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 272 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 496 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 496 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 496 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 496 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 496 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 496 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 181 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 258 bp overlap
SMARCA4 3 datasets
ChIP NGP GSE134626.SMARCA4.NGP 285 bp overlap
ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 165 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 436 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 453 bp overlap
SNAI2 3 datasets
Motif DE_24h DE_24h-SNAI2_MA0745.3 8 bp overlap
Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 375 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 345 bp overlap
SP5 1 dataset
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
TBX18 3 datasets
Motif DE_24h DE_24h-TBX18_MA1565.2 9 bp overlap
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 399 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 425 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 425 bp overlap
THAP1 3 datasets
Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap
Motif DE_36h DE_36h-THAP1_MA0597.3 8 bp overlap
Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap
TRPS1 4 datasets
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 420 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 420 bp overlap
Tcf12 2 datasets
Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Twist2 2 datasets
Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Wt1 1 dataset
Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap
ZBTB18 1 dataset
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
ZEB1 3 datasets
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZFP14 2 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
ZNF398 1 dataset
ChIP HEK293 ENCSR676ZEF.ZNF398.HEK293 231 bp overlap
ZSCAN16 1 dataset
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Zfp335 2 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Zfp961 3 datasets
Motif DE_24h DE_24h-Zfp961_MA2126.1 8 bp overlap
Motif DE_36h DE_36h-Zfp961_MA2126.1 8 bp overlap
Motif DE_48h DE_48h-Zfp961_MA2126.1 8 bp overlap
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