chr16 : 10,282,522 – 10,283,683
1,161 bp 60 TFs 4 linked genes
This 1.2 kb open chromatin element is linked to 4 target genes and is bound by 60 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000285543 55.8 kb Distal Multiome
GRIN2A 102.6 kb Distal Multiome
ATF7IP2 102.7 kb Distal Multiome
EMP2 297.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:10,277,522 – 10,288,683
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
60 transcription factors
Source
Cell type
ARID1B 1 dataset
ChIP K-562 ENCSR822CCM.ARID1B.K-562 237 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 170 bp overlap
CUX1 1 dataset
ChIP Hep-G2 ENCSR049KIZ.CUX1.Hep-G2 124 bp overlap
DPF2 1 dataset
ChIP K562 ENCFF775HUO 373 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 279 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 560 bp overlap
ChIP DE DE-FOXA2-2 618 bp overlap
GATA1 7 datasets
ChIP K-562 GSE107726.GATA1.K-562 251 bp overlap
ChIP K-562 ENCSR000EWM.GATA1.K-562 165 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 148 bp overlap
ChIP K-562_MYO1D-Non-hub_KO GSE107726.GATA1.K-562_MYO1D-Non-hub_KO 229 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 215 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 212 bp overlap
ChIP K562 ENCFF094CMK 234 bp overlap
GATA2 1 dataset
ChIP TF1 GSE73207.GATA2.TF1 237 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 1085 bp overlap
ChIP DE DE-GATA4-2 1161 bp overlap
ChIP G296S GSE85628.GATA4.G296S 190 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 190 bp overlap
ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 164 bp overlap
ChIP foregut GSE117136.GATA4.foregut 285 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 271 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 287 bp overlap
GATA6 22 datasets
ChIP AGS GSE51705.GATA6.AGS 231 bp overlap
ChIP DE DE-GATA6-1 348 bp overlap
ChIP DE DE-GATA6-1 720 bp overlap
ChIP DE DE-GATA6-2 1161 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 951 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 453 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 409 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 1161 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 392 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 372 bp overlap
ChIP H9 ERP004206.GATA6.H9 242 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 310 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 268 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 435 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 394 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 151 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 288 bp overlap
ChIP foregut GSE117136.GATA6.foregut 292 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 271 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 283 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 299 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 312 bp overlap
HDAC1 1 dataset
ChIP K-562 ENCSR387UWP.HDAC1.K-562 238 bp overlap
HDAC2 1 dataset
ChIP RH4_DMSO-6H_bioMerck GSE116344.HDAC2.RH4_DMSO-6H_bioMerck 158 bp overlap
HIC1 1 dataset
ChIP HEK293 ENCSR803GYT.HIC1.HEK293 201 bp overlap
HMBOX1 1 dataset
ChIP K-562 ENCSR757IIU.HMBOX1.K-562 199 bp overlap
HMGXB4 1 dataset
ChIP Hep-G2 ENCSR174GOO.HMGXB4.Hep-G2 143 bp overlap
HOXB13 1 dataset
Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap
Hoxa13 1 dataset
Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 638 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 264 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 847 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 745 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 421 bp overlap
KLF1 1 dataset
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
KLF10 1 dataset
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
KLF14 1 dataset
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap
KLF2 1 dataset
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
KLF4 1 dataset
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
KLF5 1 dataset
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
KLF9 1 dataset
Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap
MAFK 1 dataset
Motif DE_24h DE_24h-MAFK_MA0496.4 10 bp overlap
MYBL2 1 dataset
ChIP Hep-G2 ENCSR581KCO.MYBL2.Hep-G2 224 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 663 bp overlap
NKX2-5 2 datasets
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 250 bp overlap
ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 104 bp overlap
NR2F1 1 dataset
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 270 bp overlap
Nfat5 1 dataset
Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap
Nfatc2 1 dataset
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
PATZ1 1 dataset
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
PBX2 2 datasets
ChIP K562 ENCFF286KMN 417 bp overlap
ChIP K562 ENCFF286KMN 417 bp overlap
PDX1 1 dataset
ChIP hiPSC GSE125768.PDX1.hiPSC 213 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 632 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 643 bp overlap
RXR 1 dataset
ChIP LS180 GSE31939.RXR.LS180 108 bp overlap
SIX1 2 datasets
ChIP Hep-G2 ENCSR561BQM.SIX1.Hep-G2 275 bp overlap
ChIP HepG2 ENCFF587VYG 198 bp overlap
SIX2 3 datasets
ChIP HEK GSE73865.SIX2.HEK 189 bp overlap
ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 171 bp overlap
ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 197 bp overlap
SIX4 1 dataset
ChIP HepG2 ENCFF372NPG 162 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 538 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 523 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 689 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 781 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 899 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 536 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 587 bp overlap
SMARCA4 1 dataset
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 293 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 159 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 339 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 537 bp overlap
SP3 1 dataset
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
SRF 1 dataset
ChIP HepG2 ENCFF234ZEU 406 bp overlap
TIGD6 1 dataset
ChIP HepG2 ENCFF358XWR 577 bp overlap
TP53 2 datasets
ChIP H9 GSE142050.TP53.H9 415 bp overlap
ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 439 bp overlap
TRPS1 1 dataset
ChIP MCF-7 GSE133072.TRPS1.MCF-7 196 bp overlap
YY1 1 dataset
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 104 bp overlap
ZFP37 2 datasets
ChIP HEK293 ENCFF968PWB 254 bp overlap
ChIP HEK293 ENCSR365GRX.ZFP37.HEK293 242 bp overlap
ZNF157 1 dataset
Motif DE_24h DE_24h-ZNF157_MA2331.1 21 bp overlap
ZNF282 1 dataset
Motif DE_24h DE_24h-ZNF282_MA1154.2 15 bp overlap
ZNF30 1 dataset
ChIP HepG2 ENCFF688UNH 515 bp overlap
ZNF341 1 dataset
Motif DE_24h DE_24h-ZNF341_MA1655.2 8 bp overlap
ZNF449 1 dataset
Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap
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