chr12 : 76,038,033 – 76,038,382
349 bp 58 TFs 3 linked genes
This 349 bp open chromatin element is linked to PHLDA1-DT, PHLDA1, and PHLDA1-AS1 and is bound by 58 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PHLDA1-DT 5.4 kb Proximal Proximity
PHLDA1 6.4 kb Proximal Proximity
PHLDA1-AS1 7.5 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:76,033,033 – 76,043,382
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
58 transcription factors
Source
Cell type
ARID1A 2 datasets
ChIP MCF-7 GSE123284.ARID1A.MCF-7 127 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 267 bp overlap
ARID2 2 datasets
ChIP Aska-SS GSE108025.ARID2.Aska-SS 223 bp overlap
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 347 bp overlap
BCL3 1 dataset
ChIP A-549 ENCSR000BQH.BCL3.A-549 233 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 180 bp overlap
BRD4 6 datasets
ChIP MDA-MB-231_DMSO GSE116879.BRD4.MDA-MB-231_DMSO 261 bp overlap
ChIP MDA-MB-231_DMSO_rDNA GSE116879.BRD4.MDA-MB-231_DMSO_rDNA 261 bp overlap
ChIP MDA-MB-231_JQ1-neg_L GSE136151.BRD4.MDA-MB-231_JQ1-neg_L 177 bp overlap
ChIP MDA-MB-231_JQ1-neg_S_3f GSE136151.BRD4.MDA-MB-231_JQ1-neg_S_3f 291 bp overlap
ChIP MDA-MB-231_JQ1-pos_L GSE136151.BRD4.MDA-MB-231_JQ1-pos_L 81 bp overlap
ChIP T-47D_DMSO GSE63581.BRD4.T-47D_DMSO 172 bp overlap
BRD9 2 datasets
ChIP MDA-MB-231_DMSO GSE116879.BRD9.MDA-MB-231_DMSO 271 bp overlap
ChIP MDA-MB-231_MGSK2801 GSE116879.BRD9.MDA-MB-231_MGSK2801 153 bp overlap
CTCF 1 dataset
ChIP CD14 ENCSR000ATN.CTCF.CD14 71 bp overlap
EP300 2 datasets
ChIP MCF-7_shCtrl GSE128445.EP300.MCF-7_shCtrl 269 bp overlap
ChIP T-47D ENCSR000BLM.EP300.T-47D 127 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D49 GSE139377.ERG.aortic-endothelial-cell_D49 130 bp overlap
ESR1 11 datasets
ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 109 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 194 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 238 bp overlap
ChIP T-47D GSE72249.ESR1.T-47D 121 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 98 bp overlap
ChIP T-47D ENCSR000BJS.ESR1.T-47D 78 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 245 bp overlap
ChIP T-47D_E2 GSE72249.ESR1.T-47D_E2 105 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 75 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 168 bp overlap
ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 219 bp overlap
ESR1_Y537S 1 dataset
ChIP T-47D_E2 GSE94493.ESR1_Y537S.T-47D_E2 55 bp overlap
FOS 1 dataset
ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 87 bp overlap
FOXA1 46 datasets
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 110 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 146 bp overlap
ChIP MCF-7 GSE81714.FOXA1.MCF-7 349 bp overlap
ChIP MCF-7 ERP001226.FOXA1.MCF-7 95 bp overlap
ChIP MCF-7-TAMR-1_4OH-Tam GSE75201.FOXA1.MCF-7-TAMR-1_4OH-Tam 145 bp overlap
ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 127 bp overlap
ChIP MCF-7_JC4691 GSE126004.FOXA1.MCF-7_JC4691 145 bp overlap
ChIP MCF-7_JC4692 GSE126004.FOXA1.MCF-7_JC4692 146 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 173 bp overlap
ChIP MCF-7_JC4695 GSE126004.FOXA1.MCF-7_JC4695 187 bp overlap
ChIP MCF-7_JC4697 GSE126004.FOXA1.MCF-7_JC4697 86 bp overlap
ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 126 bp overlap
ChIP MCF-7_TamR GSE128445.FOXA1.MCF-7_TamR 296 bp overlap
ChIP MCF-7_estrogen_ab1 GSE112969.FOXA1.MCF-7_estrogen_ab1 152 bp overlap
ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 230 bp overlap
ChIP MCF-7_vehicle_ab1 GSE112969.FOXA1.MCF-7_vehicle_ab1 106 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 188 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 114 bp overlap
ChIP T-47D GSE72249.FOXA1.T-47D 207 bp overlap
ChIP T-47D_8h GSE137579.FOXA1.T-47D_8h 149 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 207 bp overlap
ChIP T-47D_DEX GSE72249.FOXA1.T-47D_DEX 170 bp overlap
ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 349 bp overlap
ChIP T-47D_E2 GSE72249.FOXA1.T-47D_E2 181 bp overlap
ChIP T-47D_E2_TAM ERP000380.FOXA1.T-47D_E2_TAM 166 bp overlap
ChIP T-47D_JC4742 GSE126004.FOXA1.T-47D_JC4742 131 bp overlap
ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 261 bp overlap
ChIP T-47D_JC4744 GSE126004.FOXA1.T-47D_JC4744 178 bp overlap
ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 186 bp overlap
ChIP T-47D_JC4746 GSE126004.FOXA1.T-47D_JC4746 140 bp overlap
ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 184 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 239 bp overlap
ChIP T-47D_flp-ctrl GSE99479.FOXA1.T-47D_flp-ctrl 141 bp overlap
ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 121 bp overlap
ChIP T-47D_shRNF2_24h GSE137579.FOXA1.T-47D_shRNF2_24h 102 bp overlap
ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 107 bp overlap
ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 349 bp overlap
ChIP ZR-75-1_estrogen_ab1 GSE112969.FOXA1.ZR-75-1_estrogen_ab1 346 bp overlap
ChIP ZR-75-1_estrogen_ab2 GSE112969.FOXA1.ZR-75-1_estrogen_ab2 349 bp overlap
ChIP ZR-75-1_vehicle_ab1 GSE112969.FOXA1.ZR-75-1_vehicle_ab1 308 bp overlap
ChIP ZR-75-1_vehicle_ab2 GSE112969.FOXA1.ZR-75-1_vehicle_ab2 284 bp overlap
ChIP ZR751 GSE72249.FOXA1.ZR751 155 bp overlap
ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 245 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 205 bp overlap
ChIP ZR751_E2_TAM ERP000380.FOXA1.ZR751_E2_TAM 127 bp overlap
ChIP breast_tumor_Male_4 GSE104399.FOXA1.breast_tumor_Male_4 222 bp overlap
FOXA2 13 datasets
ChIP BJ1-hTERT GSE90454.FOXA2.BJ1-hTERT 146 bp overlap
ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 287 bp overlap
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 80 bp overlap
ChIP BJ1-hTERT_Mimo GSE92491.FOXA2.BJ1-hTERT_Mimo 175 bp overlap
ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 71 bp overlap
ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 180 bp overlap
ChIP BJ1-hTERT_MimosinePlus GSE90454.FOXA2.BJ1-hTERT_MimosinePlus 175 bp overlap
ChIP BJ1-hTERT_Unind GSE90454.FOXA2.BJ1-hTERT_Unind 130 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 297 bp overlap
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 110 bp overlap
ChIP PANC-1 GSE119930.FOXA2.PANC-1 107 bp overlap
ChIP PANC-1_EV GSE119930.FOXA2.PANC-1_EV 146 bp overlap
ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 349 bp overlap
FOXL2 2 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 90 bp overlap
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 92 bp overlap
GATA3 1 dataset
ChIP T-47D ENCSR000BMX.GATA3.T-47D 85 bp overlap
GATA4 1 dataset
ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 349 bp overlap
GATA6 1 dataset
ChIP DE DE-GATA6-2 76 bp overlap
HDAC1 1 dataset
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.HDAC1.MCF-7_ARID1A-KO_4-OHT_clone14 113 bp overlap
HOXB13 1 dataset
ChIP G-401 GSE65381.HOXB13.G-401 89 bp overlap
IFNA1 2 datasets
ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 320 bp overlap
ChIP Huh-7_NS5 GSE110511.IFNA1.Huh-7_NS5 256 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 89 bp overlap
JUN 4 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 54 bp overlap
ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 50 bp overlap
ChIP MCF-7_TamR GSE128445.JUN.MCF-7_TamR 199 bp overlap
ChIP MCF-7_TamR_BD610326 GSE128445.JUN.MCF-7_TamR_BD610326 192 bp overlap
JUNB 1 dataset
ChIP HAEC GSE89970.JUNB.HAEC 349 bp overlap
JUND 3 datasets
ChIP SK-N-SH ENCFF551NEQ 92 bp overlap
ChIP T-47D ENCSR000BVO.JUND.T-47D 77 bp overlap
ChIP T47D ENCFF318BWX 212 bp overlap
MED1 1 dataset
ChIP hMSC-TERT4_osteoblast-4H GSE113253.MED1.hMSC-TERT4_osteoblast-4H 183 bp overlap
MYC 1 dataset
ChIP CC-LP-1 GSE124430.MYC.CC-LP-1 349 bp overlap
NR3C1 1 dataset
ChIP BEAS-2B_DEX_IA1 GSE125623.NR3C1.BEAS-2B_DEX_IA1 349 bp overlap
ONECUT1 2 datasets
ChIP HepG2 ENCFF243FIR 120 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 87 bp overlap
PAF1 1 dataset
ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 68 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 65 bp overlap
PGR 2 datasets
ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 90 bp overlap
ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 72 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 212 bp overlap
PKNOX1 3 datasets
ChIP GM12878 ENCFF589FCY 72 bp overlap
ChIP HEK293T ENCFF174WDB 64 bp overlap
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 53 bp overlap
PML 1 dataset
ChIP GM12878 ENCSR000BQM.PML.GM12878 90 bp overlap
POLR2A 2 datasets
ChIP Panc1 ENCFF290KAB 103 bp overlap
ChIP SK-N-SH ENCFF683PFH 268 bp overlap
POLR2G 3 datasets
ChIP HepG2 ENCFF241AEG 124 bp overlap
ChIP HepG2 ENCFF508UTS 124 bp overlap
ChIP HepG2 ENCFF508UTS 349 bp overlap
PRDM1 1 dataset
ChIP fetal_testis GSE100639.PRDM1.fetal_testis 155 bp overlap
RAD21 2 datasets
ChIP HEK293_siCtrl GSE130135.RAD21.HEK293_siCtrl 140 bp overlap
ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 118 bp overlap
RELA 11 datasets
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 77 bp overlap
ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 124 bp overlap
ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 73 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 99 bp overlap
ChIP aortic-endothelial-cell_IL1B_D22 GSE139377.RELA.aortic-endothelial-cell_IL1B_D22 66 bp overlap
ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 193 bp overlap
ChIP aortic-endothelial-cell_IL1B_D33 GSE139377.RELA.aortic-endothelial-cell_IL1B_D33 61 bp overlap
ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 104 bp overlap
ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 161 bp overlap
ChIP aortic-endothelial-cell_IL1B_D49 GSE139377.RELA.aortic-endothelial-cell_IL1B_D49 162 bp overlap
ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 156 bp overlap
RPA2_phospho 1 dataset
ChIP HeLa GSE108172.RPA2_phospho.HeLa 349 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 75 bp overlap
SMAD3 2 datasets
ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 321 bp overlap
ChIP HCC1954 GSE104760.SMAD3.HCC1954 71 bp overlap
SMARCA4 2 datasets
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.SMARCA4.MCF-7_ARID1A-KO_4-OHT_clone14 271 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.SMARCA4.MCF-7_ARID1A-KO_clone14 121 bp overlap
SMARCB1 2 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 245 bp overlap
ChIP MCF-7_JQ1 GSE123284.SMARCB1.MCF-7_JQ1 169 bp overlap
SMC1 1 dataset
ChIP HCAEC GSE101921.SMC1.HCAEC 287 bp overlap
SPDEF 1 dataset
ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 146 bp overlap
SPI1 2 datasets
ChIP CTV-1_delA GSE128835.SPI1.CTV-1_delA 82 bp overlap
ChIP CTV-1_delQA GSE128835.SPI1.CTV-1_delQA 77 bp overlap
STAT3 11 datasets
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 183 bp overlap
ChIP T-47D_JC4735 GSE126004.STAT3.T-47D_JC4735 265 bp overlap
ChIP T-47D_JC4737 GSE126004.STAT3.T-47D_JC4737 51 bp overlap
ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 269 bp overlap
ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 249 bp overlap
ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 204 bp overlap
ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 152 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 239 bp overlap
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 349 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 160 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 323 bp overlap
STAT5A 1 dataset
ChIP GM12878 ENCSR000BQZ.STAT5A.GM12878 198 bp overlap
SUPT5H 3 datasets
ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 228 bp overlap
ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 55 bp overlap
ChIP U2OS_siMYC GSE115365.SUPT5H.U2OS_siMYC 103 bp overlap
TEAD1 3 datasets
ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 195 bp overlap
ChIP K562 ENCFF254RJL 306 bp overlap
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 92 bp overlap
TEAD4 10 datasets
ChIP A549 ENCFF243FTL 170 bp overlap
ChIP HUCCT1 GSE68296.TEAD4.HUCCT1 123 bp overlap
ChIP Hep-G2 ENCSR000BRP.TEAD4.Hep-G2 103 bp overlap
ChIP MCF-7_BLRP_WT_E2 GSE125594.TEAD4.MCF-7_BLRP_WT_E2 111 bp overlap
ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 195 bp overlap
ChIP MCF-7_DMSO GSE125594.TEAD4.MCF-7_DMSO 50 bp overlap
ChIP MCF-7_E2 GSE125594.TEAD4.MCF-7_E2 137 bp overlap
ChIP MDA-MB-231 GSE66081.TEAD4.MDA-MB-231 229 bp overlap
ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 190 bp overlap
ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 231 bp overlap
YAP1 1 dataset
ChIP MCF-7 GSE107013.YAP1.MCF-7 66 bp overlap
YY1AP1 2 datasets
ChIP T-47D_E2 GSE125594.YY1AP1.T-47D_E2 225 bp overlap
ChIP T-47D_Veh GSE125594.YY1AP1.T-47D_Veh 264 bp overlap
ZBED1 1 dataset
ChIP GM12878 ENCSR207PFI.ZBED1.GM12878 163 bp overlap
ZNF429 1 dataset
ChIP HEK293T GSE78099.ZNF429.HEK293T 211 bp overlap
ZSCAN22 1 dataset
ChIP HEK293 GSE76494.ZSCAN22.HEK293 106 bp overlap
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