chr12 : 70,360,732 – 70,361,009

277 bp 70 TFs 1 linked gene

This 277 bp open chromatin element is linked to KCNMB4 and is bound by 70 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
KCNMB4		5.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

70 transcription factors

Ahr::Arnt 1 dataset

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

CLOCK 1 dataset

ChIP BA40_3 GSE96659.CLOCK.BA40_3 152 bp overlap

Crx 1 dataset

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_12h DE_12h-Dmbx1_MA0883.2 10 bp overlap

ELK1::HOXB13 1 dataset

Motif DE_12h DE_12h-ELK1HOXB13_MA1932.2 15 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ESR1 1 dataset

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 193 bp overlap

ETV3 1 dataset

Motif DE_12h DE_12h-ETV3_MA0763.2 9 bp overlap

EZH2 1 dataset

ChIP SF8628 GSE94834.EZH2.SF8628 171 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap

GSC 1 dataset

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

IRF4 1 dataset

Motif DE_12h DE_12h-IRF4_MA1419.2 14 bp overlap

IRF7 1 dataset

Motif DE_12h DE_12h-IRF7_MA0772.2 13 bp overlap

IRF8 1 dataset

Motif DE_12h DE_12h-IRF8_MA0652.2 13 bp overlap

IRF9 1 dataset

Motif DE_12h DE_12h-IRF9_MA0653.1 15 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 210 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 243 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 270 bp overlap

Msgn1 1 dataset

Motif DE_12h DE_12h-Msgn1_MA1524.3 10 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 277 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 277 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 277 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 277 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 270 bp overlap

ChIP hESC GSE18292.NANOG.hESC 110 bp overlap

NCOA1 1 dataset

ChIP LS180_125 GSE39277.NCOA1.LS180_125 103 bp overlap

OTX1 1 dataset

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

ChIP WTC11 ENCFF634NAO 245 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU4F2 1 dataset

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

POU5F1 13 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 204 bp overlap

ChIP H1 ENCFF698ZAP 167 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 277 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 277 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 277 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 155 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 223 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 163 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 163 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 117 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 277 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 277 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 188 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 218 bp overlap

PROX1 1 dataset

Motif DE_12h DE_12h-PROX1_MA0794.1 12 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA1555.1 14 bp overlap

RXRG 1 dataset

Motif DE_12h DE_12h-RXRG_MA1556.1 14 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 277 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 192 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 146 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 277 bp overlap

SOX2 3 datasets

ChIP hESC GSE69479.SOX2.hESC 141 bp overlap

ChIP hESC GSE18292.SOX2.hESC 155 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 226 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SREBF2 1 dataset

Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

Stat2 2 datasets

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 146 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

Thap11 1 dataset

Motif DE_12h DE_12h-Thap11_MA1573.2 14 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 214 bp overlap

ZFP14 2 datasets

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 209 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF213 2 datasets

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

Motif DE_24h DE_24h-ZNF213_MA2121.1 12 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap