chr12 : 62,104,573 – 62,105,212

639 bp 83 TFs 1 linked gene

This 639 bp open chromatin element is linked to TAFA2 and is bound by 83 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TAFA2		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

Ahr::Arnt 1 dataset

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

BCOR 1 dataset

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 262 bp overlap

BRD4 1 dataset

ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 217 bp overlap

CDX1 1 dataset

Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap

CDX4 1 dataset

Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap

CEBPA 1 dataset

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

ESR1 2 datasets

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 151 bp overlap

ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 159 bp overlap

Ebf4 1 dataset

Motif DE_12h DE_12h-Ebf4_MA2122.1 11 bp overlap

FOXA1 8 datasets

Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap

ChIP MCF-7 GSE59530.FOXA1.MCF-7 245 bp overlap

ChIP MCF-7_4OH-Tam GSE75201.FOXA1.MCF-7_4OH-Tam 113 bp overlap

ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 305 bp overlap

ChIP MCF-7_E2 GSE59530.FOXA1.MCF-7_E2 170 bp overlap

ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 197 bp overlap

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 143 bp overlap

ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 171 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 570 bp overlap

ChIP DE DE-FOXA2-2 533 bp overlap

Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_12h DE_12h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

FOXD3 2 datasets

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

FOXG1 1 dataset

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap

FOXK1 2 datasets

Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXK2 1 dataset

Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_12h DE_12h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Foxl2 1 dataset

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

GATA3 1 dataset

ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 305 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-2 381 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 537 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 243 bp overlap

ChIP DE DE-GATA6-2 350 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 639 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 639 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 547 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 289 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 639 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 639 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 443 bp overlap

HOXB9 1 dataset

Motif DE_12h DE_12h-HOXB9_MA1503.2 9 bp overlap

HOXC10 1 dataset

Motif DE_12h DE_12h-HOXC10_MA0905.2 9 bp overlap

HOXC9 1 dataset

Motif DE_12h DE_12h-HOXC9_MA0485.3 9 bp overlap

HOXD10 1 dataset

Motif DE_12h DE_12h-HOXD10_MA1506.2 10 bp overlap

HOXD11 1 dataset

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

Hoxa11 1 dataset

Motif DE_12h DE_12h-Hoxa11_MA0911.2 9 bp overlap

IRF2BP2 1 dataset

ChIP HEK293 GSE124636.IRF2BP2.HEK293 128 bp overlap

IRF9 1 dataset

Motif DE_12h DE_12h-IRF9_MA0653.1 15 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

MEIS1 3 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 133 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 639 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 600 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 466 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 424 bp overlap

ChIP hESC GSE18292.NANOG.hESC 146 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIC 1 dataset

Motif DE_12h DE_12h-NFIC_MA0161.3 7 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 177 bp overlap

PAX3 1 dataset

Motif DE_12h DE_12h-PAX3_MA1546.2 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 8 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 608 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 381 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 592 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 200 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 222 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 216 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PRDM1 1 dataset

Motif DE_12h DE_12h-PRDM1_MA0508.4 7 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RNF2 1 dataset

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 93 bp overlap

SIN3A 1 dataset

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 137 bp overlap

SIX1 1 dataset

Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 592 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 376 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 324 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 586 bp overlap

SMARCA4 3 datasets

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 297 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 288 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 318 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 292 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 283 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 97 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 206 bp overlap

Stat2 1 dataset

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 373 bp overlap

YY1AP1 1 dataset

ChIP MCF-7_Veh GSE125594.YY1AP1.MCF-7_Veh 323 bp overlap

ZBTB6 1 dataset

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF669 1 dataset

Motif DE_12h DE_12h-ZNF669_MA1985.1 15 bp overlap