Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

51 transcription factors

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 113 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 117 bp overlap

BRF1 1 dataset

ChIP H9_Activin GSE94418.BRF1.H9_Activin 148 bp overlap

CEBPG 1 dataset

ChIP K-562 ENCSR620VIC.CEBPG.K-562 209 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 148 bp overlap

DMRTA2 1 dataset

Motif DE_12h DE_12h-DMRTA2_MA1478.2 6 bp overlap

EP300 1 dataset

ChIP hESC GSE17917.EP300.hESC 402 bp overlap

GATA2 1 dataset

ChIP WA09 GSE105081.GATA2.WA09 233 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 442 bp overlap

ChIP DE DE-GATA4-2 475 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 311 bp overlap

ChIP DE DE-GATA6-2 706 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 552 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 700 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 491 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 422 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 596 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 706 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 406 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 468 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

JUN 8 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 415 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 527 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 706 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 493 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 337 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 415 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 415 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 527 bp overlap

JUND 2 datasets

ChIP H1 ENCFF468JZD 221 bp overlap

ChIP WA01 ENCSR000EBZ.JUND.WA01 130 bp overlap

KDM4B 1 dataset

ChIP K-562 ENCSR642VZY.KDM4B.K-562 131 bp overlap

KLF4 1 dataset

ChIP PDAC GSE64557.KLF4.PDAC 74 bp overlap

MSC 1 dataset

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

NANOG 8 datasets

ChIP GM23338 ENCFF065NZG 270 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 261 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 551 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 290 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 706 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 494 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 493 bp overlap

ChIP hESC GSE18292.NANOG.hESC 272 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 126 bp overlap

NIPBL 3 datasets

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 186 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 318 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 273 bp overlap

PAX6 1 dataset

Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap

POU3F1 1 dataset

ChIP SKM-1_D2 GSE93706.POU3F1.SKM-1_D2 193 bp overlap

POU4F3 1 dataset

Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap

POU5F1 7 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 544 bp overlap

ChIP GM23338 ENCFF333SNB 305 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 402 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 464 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 201 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 674 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 148 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 601 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap

SMAD2 1 dataset

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 243 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 597 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 483 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 677 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 597 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 381 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 620 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 484 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 526 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 308 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 217 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 473 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 624 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 395 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 603 bp overlap

SMARCC1 3 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 188 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 493 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 286 bp overlap

TBP 3 datasets

ChIP hESC GSE122298.TBP.hESC 185 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 172 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 133 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 370 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 322 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 245 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 205 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

Tcf21 1 dataset

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

VEZF1 2 datasets

ChIP K562 ENCFF053XDV 106 bp overlap

ChIP K562 ENCFF053XDV 322 bp overlap

ZKSCAN8 1 dataset

ChIP K562 ENCFF387ETI 128 bp overlap

ZNF197 1 dataset

ChIP K562 ENCFF872BAU 350 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 238 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR117WTM.ZNF24.K-562 656 bp overlap

ZNF395 2 datasets

ChIP K562 ENCFF464EIT 112 bp overlap

ChIP K562 ENCFF464EIT 359 bp overlap

ZNF398 1 dataset

ChIP BG01V GSE133630.ZNF398.BG01V 160 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 261 bp overlap

ZNF589 1 dataset

ChIP K562 ENCFF770FHN 304 bp overlap

ZNF766 1 dataset

ChIP K562 ENCFF348LDO 169 bp overlap

Gene	Dist. to TSS	Distance	Link type
SLC22A2	22.3 kb	Distal	Multiome
SLC22A3	107.8 kb	Distal	Multiome
IGF2R	271.5 kb	Distal	Multiome
LPAL2	279.6 kb	Distal	Multiome

Genome Browser