chr4 : 84,495,362 – 84,495,799
437 bp 60 TFs 1 linked gene
This 437 bp open chromatin element is linked to NKX6-1 and is bound by 60 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NKX6-1 1.1 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:84,490,362 – 84,500,799
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
60 transcription factors
Source
Cell type
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 324 bp overlap
CBX7 1 dataset
ChIP lymphocyte_DMSO GSE110139.CBX7.lymphocyte_DMSO 397 bp overlap
CBX8 2 datasets
ChIP H1 ENCFF095JHA 237 bp overlap
ChIP K-562 ENCSR000ATW.CBX8.K-562 434 bp overlap
CREB1 1 dataset
ChIP WA01 ENCSR000BSN.CREB1.WA01 136 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 312 bp overlap
CTCF 1 dataset
ChIP neural ENCSR822CEA.CTCF.neural 301 bp overlap
E2F6 1 dataset
ChIP WA01 ENCSR000BSI.E2F6.WA01 274 bp overlap
EOMES 1 dataset
Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap
ESR1 1 dataset
ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 300 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 20 datasets
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 437 bp overlap
ChIP GM23248 ENCFF404ZHM 189 bp overlap
ChIP GM23338 ENCFF613YON 437 bp overlap
ChIP GM23338 ENCFF886DXX 72 bp overlap
ChIP H1 ENCFF232NZA 437 bp overlap
ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 364 bp overlap
ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 172 bp overlap
ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 367 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 350 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 350 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 220 bp overlap
ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 437 bp overlap
ChIP hepatocyte ENCFF552DZB 196 bp overlap
ChIP hepatocyte ENCFF552DZB 161 bp overlap
ChIP keratinocyte ENCFF070STK 361 bp overlap
ChIP keratinocyte ENCFF070STK 150 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 261 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 384 bp overlap
ChIP neural progenitor cell ENCFF018MKA 396 bp overlap
ChIP neural progenitor cell ENCFF472NFV 437 bp overlap
EZH2_phosphoT487 2 datasets
ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 313 bp overlap
ChIP SK-N-SH ENCSR297MUV.EZH2_phosphoT487.SK-N-SH 437 bp overlap
FEZF2 1 dataset
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
GATA6 4 datasets
ChIP DE_D1 S14-DE-d1-GATA6-exp1 245 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 255 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 341 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 432 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 177 bp overlap
HOXB13 1 dataset
ChIP prostate-cancer_PDX_92 GSE130408.HOXB13.prostate-cancer_PDX_92 56 bp overlap
IKZF1 1 dataset
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 437 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 437 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 61 bp overlap
KLF1 1 dataset
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
KLF2 1 dataset
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
KLF4 1 dataset
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
KLF5 1 dataset
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
MAX 1 dataset
ChIP H1 ENCFF914VQY 357 bp overlap
MYCN 1 dataset
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 325 bp overlap
NANOG 2 datasets
ChIP WA01 ENCSR000BMT.NANOG.WA01 156 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 181 bp overlap
PARP1 1 dataset
ChIP MCF-10A GSE93038.PARP1.MCF-10A 250 bp overlap
PAX6 1 dataset
ChIP retina_pigment GSE60024.PAX6.retina_pigment 72 bp overlap
PCGF2 2 datasets
ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 191 bp overlap
ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 166 bp overlap
PDX1 1 dataset
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 182 bp overlap
POLR2A 3 datasets
ChIP esophagus muscularis mucosa ENCFF432ZCY 54 bp overlap
ChIP thyroid gland ENCFF979LRR 217 bp overlap
ChIP thyroid gland ENCFF979LRR 237 bp overlap
POU5F1 3 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 340 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 437 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 169 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 266 bp overlap
REST 2 datasets
ChIP neural ENCSR000BTV.REST.neural 140 bp overlap
ChIP neural cell ENCFF882LXX 304 bp overlap
RNF2 2 datasets
ChIP H1 ENCFF239FFS 437 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 313 bp overlap
RUNX1 1 dataset
ChIP K-562 ENCSR588AKU.RUNX1.K-562 114 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 437 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 437 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 240 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 387 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 437 bp overlap
SMARCA4 1 dataset
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 415 bp overlap
SMARCC1 1 dataset
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 203 bp overlap
SOX10 1 dataset
Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap
SP1 2 datasets
ChIP WA01 ENCSR000BIR.SP1.WA01 175 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 185 bp overlap
SUZ12 4 datasets
ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 135 bp overlap
ChIP H1 ENCFF507HGF 271 bp overlap
ChIP H1 ENCFF507HGF 112 bp overlap
ChIP H1 ENCFF881NFR 437 bp overlap
Sox11 1 dataset
Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap
TBR1 1 dataset
Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap
TBX15 1 dataset
Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap
TBX21 1 dataset
Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 388 bp overlap
TEAD4 1 dataset
ChIP ESC S26-ESC-d0-TEAD4-exp1 360 bp overlap
THAP1 1 dataset
ChIP K-562 ENCSR000BNN.THAP1.K-562 115 bp overlap
TRIM28 1 dataset
ChIP AF22 GSE84259.TRIM28.AF22 248 bp overlap
Tbx6 1 dataset
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 60 bp overlap
ZEB1 1 dataset
ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 204 bp overlap
ZNF324 1 dataset
Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap
ZNF701 2 datasets
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
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