chr22 : 32,147,169 – 32,147,709

540 bp 106 TFs 3 linked genes

This 540 bp open chromatin element is linked to SLC5A4-AS1, YWHAH, and RTCB and is bound by 106 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
SLC5A4-AS1	57.8 kb	Distal	Multiome
YWHAH	202.9 kb	Distal	Multiome
RTCB	264.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

106 transcription factors

ALX3 1 dataset

Motif DE_24h DE_24h-ALX3_MA0634.2 6 bp overlap

ARGFX 1 dataset

Motif DE_24h DE_24h-ARGFX_MA1463.2 8 bp overlap

Alx4 1 dataset

Motif DE_24h DE_24h-Alx4_MA0853.2 12 bp overlap

Arid3a 1 dataset

Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap

BCL11B 1 dataset

ChIP thymus_CD34neg GSE84677.BCL11B.thymus_CD34neg 95 bp overlap

CDX1 1 dataset

Motif DE_24h DE_24h-CDX1_MA0878.3 10 bp overlap

CREM 1 dataset

ChIP WTC11 ENCFF209ZUE 368 bp overlap

DRGX 1 dataset

Motif DE_24h DE_24h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif DE_24h DE_24h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_24h DE_24h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_24h DE_24h-EN1_MA0027.3 6 bp overlap

ESX1 1 dataset

Motif DE_24h DE_24h-ESX1_MA0644.3 7 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap

EVX1 1 dataset

Motif DE_24h DE_24h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_24h DE_24h-EVX2_MA0888.2 6 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 323 bp overlap

ChIP DE DE-GATA4-2 493 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 243 bp overlap

ChIP DE DE-GATA6-2 488 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 471 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 495 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 540 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 540 bp overlap

GSX1 1 dataset

Motif DE_24h DE_24h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_24h DE_24h-GSX2_MA0893.3 7 bp overlap

HOXA1 1 dataset

Motif DE_24h DE_24h-HOXA1_MA1495.2 6 bp overlap

HOXA10 1 dataset

Motif DE_24h DE_24h-HOXA10_MA0899.2 9 bp overlap

HOXA2 1 dataset

Motif DE_24h DE_24h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_24h DE_24h-HOXA3_MA2119.1 7 bp overlap

HOXA5 1 dataset

Motif DE_24h DE_24h-HOXA5_MA0158.2 8 bp overlap

HOXA6 1 dataset

Motif DE_24h DE_24h-HOXA6_MA1497.2 7 bp overlap

HOXB1 1 dataset

Motif DE_24h DE_24h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_24h DE_24h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_24h DE_24h-HOXB3_MA0903.2 6 bp overlap

HOXB4 1 dataset

Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap

HOXB5 1 dataset

Motif DE_24h DE_24h-HOXB5_MA0904.3 6 bp overlap

HOXB6 1 dataset

Motif DE_24h DE_24h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_24h DE_24h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_24h DE_24h-HOXB8_MA1502.2 7 bp overlap

HOXC4 1 dataset

Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap

HOXC8 1 dataset

Motif DE_24h DE_24h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif DE_24h DE_24h-HOXD3_MA0912.2 8 bp overlap

HOXD4 1 dataset

Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap

HOXD8 1 dataset

Motif DE_24h DE_24h-HOXD8_MA0910.3 7 bp overlap

HOXD9 1 dataset

Motif DE_24h DE_24h-HOXD9_MA0913.3 9 bp overlap

Hmga1 1 dataset

Motif DE_24h DE_24h-Hmga1_MA2124.1 8 bp overlap

Hmx1 1 dataset

Motif DE_24h DE_24h-Hmx1_MA0896.2 9 bp overlap

Hmx3 1 dataset

Motif DE_24h DE_24h-Hmx3_MA0898.2 9 bp overlap

Hnf1A 1 dataset

Motif DE_24h DE_24h-Hnf1A_MA1991.2 10 bp overlap

IRF7 1 dataset

Motif DE_24h DE_24h-IRF7_MA0772.2 13 bp overlap

ISX 1 dataset

Motif DE_24h DE_24h-ISX_MA0654.2 6 bp overlap

JUN 5 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 316 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 477 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 279 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 347 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 271 bp overlap

JUND 1 dataset

Motif DE_24h DE_24h-JUND_MA0492.2 11 bp overlap

LHX5 1 dataset

Motif DE_24h DE_24h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif DE_24h DE_24h-LHX6_MA0658.2 8 bp overlap

LMX1A 1 dataset

Motif DE_24h DE_24h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_24h DE_24h-LMX1B_MA0703.3 8 bp overlap

Lhx1 1 dataset

Motif DE_24h DE_24h-Lhx1_MA1518.3 10 bp overlap

Lhx4 1 dataset

Motif DE_24h DE_24h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_24h DE_24h-Lhx8_MA0705.2 6 bp overlap

MEIS1 1 dataset

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

MEOX1 1 dataset

Motif DE_24h DE_24h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_24h DE_24h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif DE_24h DE_24h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_24h DE_24h-MNX1_MA0707.3 6 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 240 bp overlap

NKX6-1 1 dataset

Motif DE_24h DE_24h-NKX6-1_MA0674.2 7 bp overlap

NKX6-2 1 dataset

Motif DE_24h DE_24h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_24h DE_24h-NOTO_MA0710.2 7 bp overlap

PAX6 1 dataset

Motif DE_24h DE_24h-PAX6_MA0069.1 14 bp overlap

PBX3 1 dataset

Motif DE_24h DE_24h-PBX3_MA1114.2 11 bp overlap

PDX1 1 dataset

Motif DE_24h DE_24h-PDX1_MA0132.3 6 bp overlap

PHOX2A 1 dataset

Motif DE_24h DE_24h-PHOX2A_MA0713.1 11 bp overlap

PKNOX1 1 dataset

Motif DE_24h DE_24h-PKNOX1_MA0782.3 10 bp overlap

POU1F1 1 dataset

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 531 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 540 bp overlap

POU6F1 1 dataset

Motif DE_24h DE_24h-POU6F1_MA0628.2 6 bp overlap

POU6F2 1 dataset

Motif DE_24h DE_24h-POU6F2_MA0793.2 9 bp overlap

PRRX1 1 dataset

Motif DE_24h DE_24h-PRRX1_MA0716.2 6 bp overlap

RAX2 1 dataset

Motif DE_24h DE_24h-RAX2_MA0717.2 6 bp overlap

SHOX 1 dataset

Motif DE_24h DE_24h-SHOX_MA0630.2 6 bp overlap

SIX2 1 dataset

Motif DE_24h DE_24h-SIX2_MA1119.2 11 bp overlap

SIX4 1 dataset

ChIP WTC11 ENCFF891HYW 169 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 273 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 540 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 540 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 540 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 540 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 540 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 368 bp overlap

SOX21 1 dataset

Motif DE_24h DE_24h-SOX21_MA0866.1 15 bp overlap

Shox2 1 dataset

Motif DE_24h DE_24h-Shox2_MA0720.2 6 bp overlap

TBX5 1 dataset

Motif DE_24h DE_24h-TBX5_MA0807.1 8 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 116 bp overlap

TGIF1 1 dataset

Motif DE_24h DE_24h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_24h DE_24h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_24h DE_24h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_24h DE_24h-TGIF2LY_MA1572.1 12 bp overlap

TLX2 1 dataset

Motif DE_24h DE_24h-TLX2_MA1577.2 6 bp overlap

UNCX 1 dataset

Motif DE_24h DE_24h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_24h DE_24h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_24h DE_24h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_24h DE_24h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_24h DE_24h-VSX2_MA0726.2 7 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCFF631OSW 284 bp overlap

ZNF257 1 dataset

Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF547 1 dataset

Motif DE_24h DE_24h-ZNF547_MA2334.1 13 bp overlap

ZNF558 1 dataset

Motif DE_24h DE_24h-ZNF558_MA2335.1 29 bp overlap

Zfp335 1 dataset

Motif DE_24h DE_24h-Zfp335_MA2002.2 7 bp overlap

mix-a 1 dataset

Motif DE_24h DE_24h-mix-a_MA0621.2 7 bp overlap