chr19 : 51,024,756 – 51,025,268
512 bp 86 TFs 1 linked gene
This 512 bp open chromatin element is linked to KLK10 and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KLK10 7.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr19:51,019,756 – 51,030,268
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 356 bp overlap
ASH2L 1 dataset
ChIP H1 ENCFF399KAM 93 bp overlap
Arid3a 1 dataset
Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap
BARX1 2 datasets
Motif DE_72h DE_72h-BARX1_MA0875.2 6 bp overlap
Motif DE_72h DE_72h-BARX1_MA0875.2 6 bp overlap
BARX2 1 dataset
Motif DE_72h DE_72h-BARX2_MA1471.2 9 bp overlap
BRD4 1 dataset
ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 512 bp overlap
BSX 2 datasets
Motif DE_72h DE_72h-BSX_MA0876.2 6 bp overlap
Motif DE_72h DE_72h-BSX_MA0876.2 6 bp overlap
CLOCK 1 dataset
ChIP BA40_3 GSE96659.CLOCK.BA40_3 150 bp overlap
CTBP1 1 dataset
ChIP MCF-7 ENCSR636EYA.CTBP1.MCF-7 226 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 251 bp overlap
DLX1 2 datasets
Motif DE_72h DE_72h-DLX1_MA0879.3 6 bp overlap
Motif DE_72h DE_72h-DLX1_MA0879.3 6 bp overlap
DLX6 2 datasets
Motif DE_72h DE_72h-DLX6_MA0882.2 6 bp overlap
Motif DE_72h DE_72h-DLX6_MA0882.2 6 bp overlap
Dlx2 1 dataset
Motif DE_72h DE_72h-Dlx2_MA0885.3 8 bp overlap
Dlx3 2 datasets
Motif DE_72h DE_72h-Dlx3_MA0880.2 6 bp overlap
Motif DE_72h DE_72h-Dlx3_MA0880.2 6 bp overlap
Dlx4 2 datasets
Motif DE_72h DE_72h-Dlx4_MA0881.2 6 bp overlap
Motif DE_72h DE_72h-Dlx4_MA0881.2 6 bp overlap
Dlx5 1 dataset
Motif DE_72h DE_72h-Dlx5_MA1476.3 8 bp overlap
ESR1 23 datasets
ChIP MCF-7 GSE76893.ESR1.MCF-7 273 bp overlap
ChIP MCF-7_E2 GSE102410.ESR1.MCF-7_E2 344 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 250 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 260 bp overlap
ChIP MCF-7_Tamoxifen GSE102410.ESR1.MCF-7_Tamoxifen 197 bp overlap
ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 181 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 385 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 373 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 411 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 223 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 311 bp overlap
ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 297 bp overlap
ChIP MCF-7_jc5853 GSE126004.ESR1.MCF-7_jc5853 258 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 213 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 362 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 272 bp overlap
ChIP MCF-7_vehicle_4h GSE99626.ESR1.MCF-7_vehicle_4h 185 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 352 bp overlap
ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 261 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 346 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 331 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 512 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 512 bp overlap
EZH2 5 datasets
ChIP A-1847 GSE95643.EZH2.A-1847 253 bp overlap
ChIP A-673 ENCSR179SAO.EZH2.A-673 358 bp overlap
ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 62 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 221 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 200 bp overlap
EZH2_phosphoT487 1 dataset
ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 232 bp overlap
FOXA1 34 datasets
ChIP MCF-7 ENCFF465LTH 323 bp overlap
ChIP MCF-7 GSE95302.FOXA1.MCF-7 189 bp overlap
ChIP MCF-7 GSE72249.FOXA1.MCF-7 286 bp overlap
ChIP MCF-7 ERP001226.FOXA1.MCF-7 238 bp overlap
ChIP MCF-7-TAMR-1_4OH-Tam GSE75201.FOXA1.MCF-7-TAMR-1_4OH-Tam 120 bp overlap
ChIP MCF-7_1117 GSE124667.FOXA1.MCF-7_1117 227 bp overlap
ChIP MCF-7_DEX GSE72249.FOXA1.MCF-7_DEX 299 bp overlap
ChIP MCF-7_DSG GSE114737.FOXA1.MCF-7_DSG 227 bp overlap
ChIP MCF-7_E2 GSE72249.FOXA1.MCF-7_E2 272 bp overlap
ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 128 bp overlap
ChIP MCF-7_E2_TAM ERP000380.FOXA1.MCF-7_E2_TAM 220 bp overlap
ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 323 bp overlap
ChIP MCF-7_JC4691 GSE126004.FOXA1.MCF-7_JC4691 309 bp overlap
ChIP MCF-7_JC4692 GSE126004.FOXA1.MCF-7_JC4692 317 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 331 bp overlap
ChIP MCF-7_JC4696 GSE126004.FOXA1.MCF-7_JC4696 203 bp overlap
ChIP MCF-7_JC4697 GSE126004.FOXA1.MCF-7_JC4697 322 bp overlap
ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 214 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 213 bp overlap
ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 237 bp overlap
ChIP T-47D_E2_TAM ERP000380.FOXA1.T-47D_E2_TAM 193 bp overlap
ChIP T-47D_JC4742 GSE126004.FOXA1.T-47D_JC4742 298 bp overlap
ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 275 bp overlap
ChIP T-47D_JC4744 GSE126004.FOXA1.T-47D_JC4744 244 bp overlap
ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 260 bp overlap
ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 258 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 283 bp overlap
ChIP T-47D_shRNF2_24h GSE137579.FOXA1.T-47D_shRNF2_24h 154 bp overlap
ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 148 bp overlap
ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 344 bp overlap
ChIP breast-cancer_Veh-2860 GSE128018.FOXA1.breast-cancer_Veh-2860 512 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 309 bp overlap
ChIP prostate_2483_T GSE130408.FOXA1.prostate_2483_T 213 bp overlap
ChIP prostate_P5_T GSE130408.FOXA1.prostate_P5_T 156 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 478 bp overlap
ChIP DE DE-FOXA2-2 488 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 258 bp overlap
FOXD3 1 dataset
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXE1 1 dataset
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
FOXG1 1 dataset
Motif DE_72h DE_72h-FOXG1_MA0613.1 8 bp overlap
FOXN3 1 dataset
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
Foxq1 1 dataset
Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap
GATA3 4 datasets
ChIP MCF-7 ENCFF352QVM 455 bp overlap
ChIP MCF-7 ENCFF437NQS 347 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 347 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 269 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 380 bp overlap
ChIP DE DE-GATA4-2 454 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 311 bp overlap
GATA6 2 datasets
ChIP DE DE-GATA6-1 398 bp overlap
ChIP DE DE-GATA6-2 455 bp overlap
GBX2 2 datasets
Motif DE_72h DE_72h-GBX2_MA0890.2 6 bp overlap
Motif DE_72h DE_72h-GBX2_MA0890.2 6 bp overlap
HDAC2 2 datasets
ChIP MCF-7 ENCFF881POI 346 bp overlap
ChIP MCF-7 ENCSR000BTP.HDAC2.MCF-7 150 bp overlap
HESX1 2 datasets
Motif DE_72h DE_72h-HESX1_MA0894.2 6 bp overlap
Motif DE_72h DE_72h-HESX1_MA0894.2 6 bp overlap
HOXA10 1 dataset
Motif DE_72h DE_72h-HOXA10_MA0899.2 9 bp overlap
HOXA7 2 datasets
Motif DE_72h DE_72h-HOXA7_MA1498.3 6 bp overlap
Motif DE_72h DE_72h-HOXA7_MA1498.3 6 bp overlap
HOXB13 2 datasets
Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap
ChIP prostate-cancer_PDX_141 GSE130408.HOXB13.prostate-cancer_PDX_141 119 bp overlap
HOXD9 1 dataset
Motif DE_72h DE_72h-HOXD9_MA0913.3 9 bp overlap
Hmx1 1 dataset
Motif DE_72h DE_72h-Hmx1_MA0896.2 9 bp overlap
Hmx2 1 dataset
Motif DE_72h DE_72h-Hmx2_MA0897.2 15 bp overlap
Hmx3 2 datasets
Motif DE_72h DE_72h-Hmx3_MA0898.2 9 bp overlap
Motif DE_72h DE_72h-Hmx3_MA0898.2 9 bp overlap
ISL2 1 dataset
Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP MCF-7_E2 GSE102410.JUN.MCF-7_E2 213 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 512 bp overlap
KDM5B 1 dataset
ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 134 bp overlap
LBX2 2 datasets
Motif DE_72h DE_72h-LBX2_MA0699.2 6 bp overlap
Motif DE_72h DE_72h-LBX2_MA0699.2 6 bp overlap
LHX2 2 datasets
Motif DE_72h DE_72h-LHX2_MA0700.3 6 bp overlap
Motif DE_72h DE_72h-LHX2_MA0700.3 6 bp overlap
MSX1 2 datasets
Motif DE_72h DE_72h-MSX1_MA0666.3 6 bp overlap
Motif DE_72h DE_72h-MSX1_MA0666.3 6 bp overlap
MSX2 4 datasets
Motif DE_72h DE_72h-MSX2_MA0708.3 6 bp overlap
Motif DE_72h DE_72h-MSX2_MA0708.3 6 bp overlap
ChIP MCF-7 ENCFF179YRV 297 bp overlap
ChIP MCF-7 ENCSR604WXQ.MSX2.MCF-7 360 bp overlap
Msx3 2 datasets
Motif DE_72h DE_72h-Msx3_MA0709.2 6 bp overlap
Motif DE_72h DE_72h-Msx3_MA0709.2 6 bp overlap
NELFE 1 dataset
ChIP K-562_HS GSE112379.NELFE.K-562_HS 159 bp overlap
NFIB 1 dataset
Motif DE_72h DE_72h-NFIB_MA1643.2 17 bp overlap
NFIC 1 dataset
Motif DE_72h DE_72h-NFIC_MA1527.2 15 bp overlap
NFIC::TLX1 1 dataset
Motif DE_72h DE_72h-NFICTLX1_MA0119.1 14 bp overlap
NKX2-1 1 dataset
ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 211 bp overlap
NR2F2 2 datasets
ChIP MCF-7 ENCFF329FZB 353 bp overlap
ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 249 bp overlap
Nkx3-2 1 dataset
Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap
Nobox 2 datasets
Motif DE_72h DE_72h-Nobox_MA0125.2 6 bp overlap
Motif DE_72h DE_72h-Nobox_MA0125.2 6 bp overlap
OSR2 3 datasets
ChIP HEK293 ENCFF875BDB 373 bp overlap
ChIP HEK293 ENCFF875BDB 161 bp overlap
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 258 bp overlap
PAX3 1 dataset
Motif DE_72h DE_72h-PAX3_MA0780.1 10 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 385 bp overlap
PRDM9 1 dataset
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
Pax7 1 dataset
Motif DE_72h DE_72h-Pax7_MA0680.3 10 bp overlap
RAX 2 datasets
Motif DE_72h DE_72h-RAX_MA0718.2 6 bp overlap
Motif DE_72h DE_72h-RAX_MA0718.2 6 bp overlap
RORC 1 dataset
ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 52 bp overlap
SIN3A 1 dataset
ChIP MCF-7 ENCSR000BUM.SIN3A.MCF-7 176 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 284 bp overlap
SMARCA4 1 dataset
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 164 bp overlap
SOX14 1 dataset
Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 295 bp overlap
SOX18 2 datasets
Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap
Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap
SP1 1 dataset
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
SP4 1 dataset
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 1 dataset
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPDEF 1 dataset
ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 171 bp overlap
SREBP2 1 dataset
ChIP HCC70 GSE126380.SREBP2.HCC70 90 bp overlap
SRY 2 datasets
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
SS18 1 dataset
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SS18.BIN-67_lentivirus-SMARCA4-K785R 221 bp overlap
STAT3 4 datasets
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 300 bp overlap
ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 344 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 221 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 224 bp overlap
TLE3 1 dataset
ChIP LNCaP_r1881 GSE94682.TLE3.LNCaP_r1881 238 bp overlap
VENTX 1 dataset
Motif DE_72h DE_72h-VENTX_MA0724.1 9 bp overlap
Wt1 1 dataset
Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap
ZNF148 1 dataset
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF263 1 dataset
Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap
ZNF281 1 dataset
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF460 1 dataset
Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 104 bp overlap
ZNF687 1 dataset
ChIP MCF-7 ENCSR899BKM.ZNF687.MCF-7 191 bp overlap
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