Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

ASCL1 1 dataset

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 129 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 236 bp overlap

ChIP K562 ENCFF673OEZ 362 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 271 bp overlap

CTCF 1 dataset

ChIP U-937 ERP008568.CTCF.U-937 245 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 152 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 180 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 252 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 226 bp overlap

ETS1 2 datasets

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 234 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 64 bp overlap

FOS 1 dataset

ChIP IMR-90 ENCSR124AIG.FOS.IMR-90 95 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 362 bp overlap

ChIP DE DE-FOXA2-2 362 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 187 bp overlap

GATA1 2 datasets

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 185 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 218 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 362 bp overlap

ChIP DE DE-GATA4-2 362 bp overlap

ChIP foregut GSE117136.GATA4.foregut 353 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 362 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 362 bp overlap

GATA6 15 datasets

ChIP DE DE-GATA6-1 362 bp overlap

ChIP DE DE-GATA6-2 362 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 362 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 362 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 357 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 362 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 362 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 362 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 226 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 362 bp overlap

ChIP foregut GSE117136.GATA6.foregut 362 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 362 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 362 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 298 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 362 bp overlap

GRHL2 1 dataset

ChIP LNCaP GSE80256.GRHL2.LNCaP 239 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR563YDA.HDGF.K-562 362 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 173 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 167 bp overlap

JUN 1 dataset

ChIP 786-O GSE86092.JUN.786-O 177 bp overlap

JUNB 1 dataset

ChIP K-562 ENCSR000DJY.JUNB.K-562 81 bp overlap

KDM1A 2 datasets

ChIP K-562 GSE117944.KDM1A.K-562 163 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 199 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 205 bp overlap

LDB1 1 dataset

ChIP K-562 GSE142227.LDB1.K-562 175 bp overlap

MAX 1 dataset

ChIP H1 ENCFF914VQY 109 bp overlap

MAZ 1 dataset

ChIP K-562 ENCSR000EFX.MAZ.K-562 100 bp overlap

NCOA2 1 dataset

ChIP MCF-7 ERP000901.NCOA2.MCF-7 127 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 61 bp overlap

NKX2-5 2 datasets

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 230 bp overlap

ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 157 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 172 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 192 bp overlap

PDX1 1 dataset

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 89 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 309 bp overlap

RCOR1 1 dataset

ChIP IMR-90 ENCSR000EFG.RCOR1.IMR-90 55 bp overlap

REST 1 dataset

ChIP K-562 ENCSR000BMW.REST.K-562 117 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 155 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 348 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 224 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 164 bp overlap

SMARCA4 3 datasets

ChIP A-549_AG15686 GSE132290.SMARCA4.A-549_AG15686 107 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 333 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 194 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 362 bp overlap

SPI1 1 dataset

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 148 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 214 bp overlap

TAL1 4 datasets

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 166 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 181 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 164 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 177 bp overlap

TBP 1 dataset

ChIP K-562 GSE55306.TBP.K-562 265 bp overlap

TCF3 1 dataset

ChIP K-562 ENCSR970OJY.TCF3.K-562 207 bp overlap

USF1 3 datasets

ChIP H1 ENCFF090WVU 147 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 128 bp overlap

ChIP WTC11 ENCFF699QGS 256 bp overlap

USF2 2 datasets

ChIP WA01 ENCSR000ECD.USF2.WA01 86 bp overlap

ChIP WTC11 ENCFF139JAW 252 bp overlap

WT1 1 dataset

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 226 bp overlap

ZBTB6 1 dataset

ChIP HEK293 GSE76494.ZBTB6.HEK293 190 bp overlap

ZEB2 3 datasets

ChIP K-562 ENCSR004GKA.ZEB2.K-562 298 bp overlap

ChIP K-562 ENCSR322CFO.ZEB2.K-562 194 bp overlap

ChIP K562 ENCFF795CMH 335 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 335 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 257 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 302 bp overlap

ZNF574 1 dataset

ChIP HEK293 GSE76494.ZNF574.HEK293 313 bp overlap

ZSCAN29 2 datasets

ChIP K-562 ENCSR175SZH.ZSCAN29.K-562 362 bp overlap

ChIP K562 ENCFF797SOU 359 bp overlap

Gene	Expression	Dist. to TSS	Distance	Link type
MPPE1		5.2 kb	Proximal	Proximity
ENSG00000273141		5.6 kb	Proximal	Proximity

Genome Browser