chr17 : 57,536,308 – 57,536,893
585 bp 75 TFs 1 linked gene
This 585 bp open chromatin element is linked to MSI2 and is bound by 75 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MSI2 280.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr17:57,531,308 – 57,541,893
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
75 transcription factors
Source
Cell type
Ahr::Arnt 2 datasets
Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
BHLHE22 1 dataset
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
BRD4 11 datasets
ChIP BE2C GSE80151.BRD4.BE2C 122 bp overlap
ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 164 bp overlap
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 271 bp overlap
ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 102 bp overlap
ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 193 bp overlap
ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 338 bp overlap
ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 234 bp overlap
ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 309 bp overlap
ChIP SK-N-BE2-C GSE80151.BRD4.SK-N-BE2-C 122 bp overlap
ChIP retina_AB1-FW13 GSE86981.BRD4.retina_AB1-FW13 278 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 104 bp overlap
Bhlha15 1 dataset
Motif DE_60h DE_60h-Bhlha15_MA1472.3 8 bp overlap
CEBPG 1 dataset
ChIP MCF-7 ENCFF155HZI 275 bp overlap
CREB1 4 datasets
Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 141 bp overlap
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 295 bp overlap
ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 208 bp overlap
CREB3L1 1 dataset
Motif DE_60h DE_60h-CREB3L1_MA0839.2 13 bp overlap
CRX 2 datasets
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 283 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 304 bp overlap
CTCF 2 datasets
ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 297 bp overlap
ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 348 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 515 bp overlap
EGR1 2 datasets
Motif DE_36h DE_36h-EGR1_MA0162.5 10 bp overlap
Motif DE_60h DE_60h-EGR1_MA0162.5 10 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 521 bp overlap
ERF::FOXO1 1 dataset
Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXA1 4 datasets
ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 74 bp overlap
ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 314 bp overlap
ChIP primary-breast-cancer_B2_DSG GSE114737.FOXA1.primary-breast-cancer_B2_DSG 111 bp overlap
ChIP primary-breast-cancer_B4_DSG GSE114737.FOXA1.primary-breast-cancer_B4_DSG 88 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 585 bp overlap
ChIP DE DE-FOXA2-2 585 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 582 bp overlap
ChIP DE DE-GATA4-2 578 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 506 bp overlap
ChIP DE DE-GATA6-2 563 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 582 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 585 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 462 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 569 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 585 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 585 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 525 bp overlap
GFI1 1 dataset
Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap
GLI3 1 dataset
Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap
GLIS1 1 dataset
Motif DE_60h DE_60h-GLIS1_MA0735.2 15 bp overlap
GLIS2 1 dataset
Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap
GTF3A 1 dataset
ChIP HepG2 ENCFF268DGX 143 bp overlap
Gfi1B 1 dataset
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
HES1 1 dataset
ChIP MCF-7 ENCFF537SCW 209 bp overlap
HLF 2 datasets
ChIP Hep-G2 ENCSR528PSI.HLF.Hep-G2 131 bp overlap
ChIP HepG2 ENCFF854JLR 190 bp overlap
Hand1 1 dataset
Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 202 bp overlap
JUN 2 datasets
Motif DE_60h DE_60h-JUN_MA0488.2 10 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 322 bp overlap
KLF17 2 datasets
Motif DE_36h DE_36h-KLF17_MA1514.2 14 bp overlap
Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap
KMT2A 1 dataset
ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 218 bp overlap
MEF2D 1 dataset
ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 255 bp overlap
MEIS1 1 dataset
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MSC 1 dataset
Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap
MYCN 1 dataset
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 243 bp overlap
MYF5 1 dataset
Motif DE_60h DE_60h-MYF5_MA1641.2 8 bp overlap
NEUROD1 5 datasets
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 361 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 585 bp overlap
ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 423 bp overlap
ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 515 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NFE2L2 1 dataset
ChIP A-549 GSE113497.NFE2L2.A-549 301 bp overlap
NR2C2 1 dataset
ChIP K562 ENCFF750AXF 234 bp overlap
NRL 1 dataset
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Neurod2 2 datasets
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
OSR2 1 dataset
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 235 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 262 bp overlap
Olig2 1 dataset
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 333 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 509 bp overlap
Ptf1A 1 dataset
Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap
RBM22 1 dataset
ChIP HepG2 ENCFF292RVQ 141 bp overlap
RORB 1 dataset
ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 357 bp overlap
SMAD2 2 datasets
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 296 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 562 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 543 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 428 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 363 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 577 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 298 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 585 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 581 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 166 bp overlap
SMARCC1 3 datasets
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 513 bp overlap
ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 230 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 495 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 310 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 326 bp overlap
SP4 1 dataset
ChIP HepG2 ENCFF865DSQ 385 bp overlap
SREBF2 1 dataset
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
SS18 1 dataset
ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 427 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 389 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 374 bp overlap
TAL1::TCF3 1 dataset
Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap
TFAP4 1 dataset
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
THAP1 2 datasets
Motif DE_36h DE_36h-THAP1_MA0597.3 8 bp overlap
Motif DE_60h DE_60h-THAP1_MA0597.3 8 bp overlap
TRIM28 1 dataset
ChIP AF22 GSE84259.TRIM28.AF22 243 bp overlap
Tcf12 1 dataset
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Tcf21 1 dataset
Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap
Twist2 1 dataset
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Wt1 2 datasets
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap
ZBTB20 1 dataset
ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 106 bp overlap
ZHX2 1 dataset
ChIP HepG2 ENCFF614TEV 148 bp overlap
ZNF320 1 dataset
ChIP HEK293 GSE76494.ZNF320.HEK293 70 bp overlap
ZNF366 1 dataset
ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 283 bp overlap
ZNF549 4 datasets
Motif DE_36h DE_36h-ZNF549_MA1728.2 8 bp overlap
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
ZNF587 1 dataset
ChIP HEK293T GSE78099.ZNF587.HEK293T 119 bp overlap
Zic2 1 dataset
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Huangfu Lab · Publications · Resources · Contact