Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

60 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 350 bp overlap

BRD2 1 dataset

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 338 bp overlap

BRD4 2 datasets

ChIP GM15850_DMSO GSE99402.BRD4.GM15850_DMSO 254 bp overlap

ChIP GM15850_Syn-TEF1 GSE99402.BRD4.GM15850_Syn-TEF1 214 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF031ISE 255 bp overlap

ChIP BLaER1 ENCFF262VBH 76 bp overlap

ChIP BLaER1 ENCFF274GAT 366 bp overlap

ChIP BLaER1 ENCFF460KDD 291 bp overlap

Crx 1 dataset

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

DPF2 1 dataset

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 228 bp overlap

Dmbx1 1 dataset

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

EBF1 5 datasets

Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap

ChIP GM12878 ENCFF167CZS 321 bp overlap

ChIP GM12878 ENCFF813OXE 122 bp overlap

ChIP GM12878 ENCSR000DZQ.EBF1.GM12878 260 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 305 bp overlap

EBF3 1 dataset

Motif DE_72h DE_72h-EBF3_MA1637.2 9 bp overlap

ELF1 1 dataset

ChIP GM12878 ENCSR841NDX.ELF1.GM12878 288 bp overlap

ESR1 7 datasets

ChIP T-47D GSE148277.ESR1.T-47D 209 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 252 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 314 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 332 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 159 bp overlap

ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 164 bp overlap

ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 164 bp overlap

Ebf2 1 dataset

Motif DE_72h DE_72h-Ebf2_MA1604.2 9 bp overlap

Ebf4 1 dataset

Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 298 bp overlap

ChIP DE DE-FOXA2-2 266 bp overlap

GATA3 1 dataset

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 358 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 455 bp overlap

ChIP DE DE-GATA4-2 481 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 462 bp overlap

ChIP DE DE-GATA6-2 531 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 446 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 451 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 485 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 565 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 549 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 450 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 441 bp overlap

GSC 1 dataset

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 270 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 328 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 345 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 306 bp overlap

KLF1 1 dataset

Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap

KLF14 1 dataset

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF2 1 dataset

Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap

KLF4 1 dataset

Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

MED1 1 dataset

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 274 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 465 bp overlap

MEIS1 1 dataset

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MXI1 1 dataset

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

MYB 1 dataset

ChIP THP-1 GSE90769.MYB.THP-1 383 bp overlap

MZF1 1 dataset

Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap

NR3C1 1 dataset

ChIP breast_tumor_Male_21 GSE104399.NR3C1.breast_tumor_Male_21 311 bp overlap

OTX1 1 dataset

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

RELA 1 dataset

ChIP GM19099 ENCSR000EBI.RELA.GM19099 191 bp overlap

RFX1 1 dataset

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 261 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

RUNX1 1 dataset

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 527 bp overlap

Rhox11 1 dataset

Motif DE_72h DE_72h-Rhox11_MA0629.2 9 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 565 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 565 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 423 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 273 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 413 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 445 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 495 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 551 bp overlap

SMARCA4 1 dataset

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 184 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 410 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 565 bp overlap

SPI1 7 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 179 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 173 bp overlap

ChIP GM12878 ENCFF134LCP 215 bp overlap

ChIP HL-60 ENCFF645GBT 225 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 154 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 128 bp overlap

ChIP U-937 GSE128834.SPI1.U-937 222 bp overlap

TAL1 1 dataset

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 141 bp overlap

TCF12 1 dataset

ChIP GM12878 ENCSR000BGZ.TCF12.GM12878 123 bp overlap

TFAP2A 1 dataset

Motif DE_72h DE_72h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 1 dataset

Motif DE_72h DE_72h-TFAP2B_MA0811.2 11 bp overlap

TFAP2C 1 dataset

Motif DE_72h DE_72h-TFAP2C_MA0524.3 11 bp overlap

TFAP2E 1 dataset

Motif DE_72h DE_72h-TFAP2E_MA1569.2 9 bp overlap

Yy1 1 dataset

Motif DE_72h DE_72h-Yy1_MA0095.4 8 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF740 1 dataset

Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap

ZNF816 1 dataset

Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap

Gene	Dist. to TSS	Distance	Link type
ENSG00000108516	at TSS	At TSS	Proximity
KRT19	193.7 kb	Distal	Multiome
KRT10	512.0 kb	Distal	Multiome+HiCAR

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