chr10 : 105,844,701 – 105,845,334

633 bp 68 TFs 1 linked gene

This 633 bp open chromatin element is linked to ENSG00000287732 and is bound by 68 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000287732		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

ASCL1 1 dataset

Motif ES_0h ES_0h-ASCL1_MA1100.3 8 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 60 bp overlap

ATOH7 1 dataset

Motif DE_12h DE_12h-ATOH7_MA1468.1 10 bp overlap

Ascl2 1 dataset

Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap

BHLHE22 1 dataset

Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap

BRD4 6 datasets

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 249 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 207 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_KCl-pos_JQ1-neg 297 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 252 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-pos 260 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 389 bp overlap

Bhlha15 1 dataset

Motif ES_0h ES_0h-Bhlha15_MA1472.3 8 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 349 bp overlap

CTCF 2 datasets

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 139 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF277CZQ 163 bp overlap

E2F7 1 dataset

Motif DE_12h DE_12h-E2F7_MA0758.1 14 bp overlap

EP300 2 datasets

ChIP gastroesophageal sphincter ENCFF211FPL 78 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 559 bp overlap

ESR2 1 dataset

Motif DE_12h DE_12h-ESR2_MA0258.2 15 bp overlap

EZH2_phosphoT487 1 dataset

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 157 bp overlap

FOXA1 1 dataset

Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 368 bp overlap

Motif ES_0h ES_0h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif ES_0h ES_0h-FOXA3_MA1683.2 7 bp overlap

FOXC1 1 dataset

Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif ES_0h ES_0h-FOXD1_MA0031.2 7 bp overlap

FOXG1 1 dataset

Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap

FOXH1 2 datasets

Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap

FOXI1 1 dataset

Motif ES_0h ES_0h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif ES_0h ES_0h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif ES_0h ES_0h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif ES_0h ES_0h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif ES_0h ES_0h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif ES_0h ES_0h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif ES_0h ES_0h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif ES_0h ES_0h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif ES_0h ES_0h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif ES_0h ES_0h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif ES_0h ES_0h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif ES_0h ES_0h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif ES_0h ES_0h-Foxj2_MA0614.1 8 bp overlap

Foxl2 1 dataset

Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif ES_0h ES_0h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif ES_0h ES_0h-Foxo3_MA0157.4 7 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HIC2 2 datasets

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

ISL2 1 dataset

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

MYF5 1 dataset

Motif ES_0h ES_0h-MYF5_MA1641.2 8 bp overlap

MYOD1 1 dataset

Motif ES_0h ES_0h-MYOD1_MA0499.3 9 bp overlap

MYOG 1 dataset

Motif ES_0h ES_0h-MYOG_MA0500.3 8 bp overlap

NANOG 6 datasets

ChIP GM23338 ENCFF065NZG 127 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 99 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 225 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 102 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 460 bp overlap

ChIP hESC GSE18292.NANOG.hESC 89 bp overlap

NEUROG1 1 dataset

Motif DE_12h DE_12h-NEUROG1_MA0623.2 10 bp overlap

NEUROG2 2 datasets

Motif DE_12h DE_12h-NEUROG2_MA0669.1 10 bp overlap

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NR4A2::RXRA 1 dataset

Motif DE_12h DE_12h-NR4A2RXRA_MA1147.2 13 bp overlap

Neurod2 1 dataset

Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap

PBX3 1 dataset

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

PGR 1 dataset

Motif DE_12h DE_12h-PGR_MA2327.1 9 bp overlap

PKNOX1 1 dataset

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

POLR2A 1 dataset

ChIP gastroesophageal sphincter ENCFF070PCA 140 bp overlap

POU5F1 3 datasets

Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 224 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 323 bp overlap

Ptf1A 1 dataset

Motif ES_0h ES_0h-Ptf1A_MA1619.2 8 bp overlap

RBPJ 1 dataset

ChIP GSC8-11_12d-das GSE74557.RBPJ.GSC8-11_12d-das 520 bp overlap

REST 2 datasets

ChIP hippocampus GSE144226.REST.hippocampus 51 bp overlap

ChIP neural ENCSR000BTV.REST.neural 191 bp overlap

SMC3 1 dataset

ChIP neural ENCSR404BPV.SMC3.neural 176 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 597 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 67 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 60 bp overlap

SP5 2 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

STAT3 1 dataset

ChIP A139 GSE85579.STAT3.A139 170 bp overlap

TFAP4 1 dataset

Motif DE_12h DE_12h-TFAP4_MA1570.1 10 bp overlap

Tcf12 1 dataset

Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap

ZKSCAN5 1 dataset

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZSCAN31 2 datasets

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap

Motif ES_0h ES_0h-ZSCAN31_MA1722.2 18 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap