chr10 : 88,375,677 – 88,376,274
597 bp 61 TFs 2 linked genes
This 597 bp open chromatin element is linked to RNLS and PTEN and is bound by 61 transcription factors.
Linked Genes
2 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
RNLS 207.2 kb Distal Multiome
PTEN 512.4 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:88,370,677 – 88,381,274
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
61 transcription factors
Source
Cell type
ARNT::HIF1A 2 datasets
Motif DE_36h DE_36h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
ATOH7 1 dataset
Motif DE_48h DE_48h-ATOH7_MA1468.1 10 bp overlap
BRD4 2 datasets
ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 579 bp overlap
ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 345 bp overlap
Dmrt1 1 dataset
Motif DE_48h DE_48h-Dmrt1_MA1603.2 9 bp overlap
EBF1 3 datasets
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
EOMES 4 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 339 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D26 GSE139377.ERG.aortic-endothelial-cell_D26 168 bp overlap
ESR1 2 datasets
Motif DE_48h DE_48h-ESR1_MA0112.4 15 bp overlap
Motif DE_60h DE_60h-ESR1_MA0112.4 15 bp overlap
ESR2 2 datasets
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
Ebf4 3 datasets
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
Elf5 3 datasets
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 307 bp overlap
ChIP DE DE-FOXA2-2 301 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 481 bp overlap
ChIP DE DE-GATA4-2 539 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 557 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 254 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 505 bp overlap
ChIP DE DE-GATA6-2 586 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 396 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 543 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 495 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 512 bp overlap
ChIP foregut GSE117136.GATA6.foregut 535 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 318 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
IKZF1 1 dataset
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
IKZF2 4 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
KLF5 3 datasets
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
MAZ 3 datasets
Motif DE_36h DE_36h-MAZ_MA1522.2 8 bp overlap
Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap
Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap
MEIS1 1 dataset
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MGA::EVX1 3 datasets
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
MZF1 2 datasets
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
NR1I2 2 datasets
Motif DE_48h DE_48h-NR1I2_MA1533.2 15 bp overlap
Motif DE_60h DE_60h-NR1I2_MA1533.2 15 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 258 bp overlap
PPARG 2 datasets
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
RBPJ 3 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
RXRA::VDR 2 datasets
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
RXRG 2 datasets
Motif DE_48h DE_48h-RXRG_MA1556.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA1556.1 14 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 302 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 563 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 269 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 492 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 518 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 277 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 277 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 433 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 511 bp overlap
SP4 3 datasets
Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPI1 1 dataset
ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 122 bp overlap
SRF 1 dataset
Motif DE_48h DE_48h-SRF_MA0083.3 16 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
TBR1 3 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX1 3 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 3 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 3 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 3 datasets
Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX21 3 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
TBX3 3 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TBX4 3 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TBX5 3 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tbx6 3 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
YY1 1 dataset
ChIP ALL GSE145549.YY1.ALL 104 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 233 bp overlap
ZNF148 3 datasets
Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap
ZNF24 1 dataset
Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap
ZNF528 4 datasets
Motif DE_36h DE_36h-ZNF528_MA1597.1 17 bp overlap
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap
ChIP HEK293 GSE76494.ZNF528.HEK293 252 bp overlap
ZNF558 2 datasets
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap
ZNF680 3 datasets
Motif DE_36h DE_36h-ZNF680_MA1729.2 11 bp overlap
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Huangfu Lab · Publications · Resources · Contact