chr8 : 74,330,875 – 74,331,280

405 bp 51 TFs 1 linked gene

This 405 bp open chromatin element is linked to JPH1 and is bound by 51 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
JPH1		9.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

51 transcription factors

APC 1 dataset

ChIP HCT-116 GSE103894.APC.HCT-116 334 bp overlap

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 152 bp overlap

BCL6 1 dataset

Motif DE_36h DE_36h-BCL6_MA0463.3 13 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 341 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 221 bp overlap

CTCF 1 dataset

ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 218 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 263 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 150 bp overlap

E2F7 1 dataset

Motif DE_36h DE_36h-E2F7_MA0758.1 14 bp overlap

ELF1 1 dataset

Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap

ELF3 1 dataset

Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 293 bp overlap

ERF::NHLH1 1 dataset

Motif DE_36h DE_36h-ERFNHLH1_MA1938.2 16 bp overlap

ESR1 1 dataset

ChIP breast_tumor_Male_16 GSE104399.ESR1.breast_tumor_Male_16 373 bp overlap

ETS1 1 dataset

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 164 bp overlap

GATA6 5 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 375 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 138 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 262 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 352 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 326 bp overlap

Hnf1A 1 dataset

Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap

Ikzf3 1 dataset

Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap

JUN 2 datasets

ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 338 bp overlap

LIN54 1 dataset

Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap

Lef1 1 dataset

Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap

MYC 1 dataset

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 258 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 358 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 195 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 371 bp overlap

NIPBL 3 datasets

ChIP hESC GSE64758.NIPBL.hESC 196 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 227 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 222 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BHF.NR3C1.A-549 142 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 305 bp overlap

Plagl1 1 dataset

Motif DE_36h DE_36h-Plagl1_MA1615.2 8 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm4 1 dataset

Motif DE_36h DE_36h-Prdm4_MA1647.3 11 bp overlap

REL 1 dataset

Motif DE_36h DE_36h-REL_MA0101.1 10 bp overlap

RORA 2 datasets

Motif DE_36h DE_36h-RORA_MA0071.1 10 bp overlap

Motif DE_36h DE_36h-RORA_MA0072.2 11 bp overlap

RORB 1 dataset

Motif DE_36h DE_36h-RORB_MA1150.2 10 bp overlap

RORC 1 dataset

Motif DE_36h DE_36h-RORC_MA1151.2 10 bp overlap

Rarg 1 dataset

Motif DE_36h DE_36h-Rarg_MA0859.2 15 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 349 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 376 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 335 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 341 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 204 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 236 bp overlap

SPI1 1 dataset

ChIP primary-neutrophil_donorE GSE128834.SPI1.primary-neutrophil_donorE 103 bp overlap

STAT1 1 dataset

Motif DE_36h DE_36h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

Motif DE_36h DE_36h-STAT3_MA0144.3 9 bp overlap

Stat4 1 dataset

Motif DE_36h DE_36h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_36h DE_36h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_36h DE_36h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_36h DE_36h-Stat5b_MA1625.2 9 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 378 bp overlap

ZNF398 1 dataset

ChIP BG01V GSE133630.ZNF398.BG01V 158 bp overlap

ZNF418 1 dataset

Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 289 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 405 bp overlap

ZNF708 1 dataset

Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap

ZNF85 1 dataset

Motif DE_36h DE_36h-ZNF85_MA1720.2 12 bp overlap