chr8 : 69,194,435 – 69,195,315

880 bp 72 TFs 0 linked genes

This 880 bp open chromatin element has no linked target genes and is bound by 72 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

72 transcription factors

ASXL3 1 dataset

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 237 bp overlap

ATOH7 1 dataset

Motif DE_60h DE_60h-ATOH7_MA1468.1 10 bp overlap

Ascl2 1 dataset

Motif DE_60h DE_60h-Ascl2_MA0816.1 10 bp overlap

BRD4 2 datasets

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 356 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 232 bp overlap

CHD4 1 dataset

ChIP SCMC GSE155861.CHD4.SCMC 869 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 459 bp overlap

EHMT2 1 dataset

ChIP Rh41 GSE118666.EHMT2.Rh41 163 bp overlap

EOMES 2 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 324 bp overlap

ERG 1 dataset

ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 139 bp overlap

FOXA1 1 dataset

ChIP LNCaP GSE64656.FOXA1.LNCaP 183 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 880 bp overlap

ChIP DE DE-FOXA2-2 845 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 314 bp overlap

FOXO1-PAX3 2 datasets

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 438 bp overlap

ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 422 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 246 bp overlap

ChIP DE DE-GATA4-1 619 bp overlap

ChIP DE DE-GATA4-2 739 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 311 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 568 bp overlap

ChIP DE DE-GATA6-2 723 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 491 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 631 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 499 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 540 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 695 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 548 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 378 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 284 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 330 bp overlap

Gata3 2 datasets

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

Hnf1A 2 datasets

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

ISL2 1 dataset

Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap

JUN 1 dataset

ChIP DE_D1 S40-DE-d1-JUN-exp2 332 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 444 bp overlap

MAFF 1 dataset

Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap

MEIS1 1 dataset

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

MGA 1 dataset

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 558 bp overlap

MYOG 1 dataset

ChIP RH4_DMSO-6H GSE116344.MYOG.RH4_DMSO-6H 236 bp overlap

Mafb 1 dataset

Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap

NEUROG2 1 dataset

Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 388 bp overlap

NRL 1 dataset

Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH3 GSE83726.PAX3-FOXO1.RH3 368 bp overlap

PAX6 1 dataset

ChIP EndoC-betaH2 GSE87530.PAX6.EndoC-betaH2 421 bp overlap

PAX7 1 dataset

ChIP H9_DOX GSE98976.PAX7.H9_DOX 235 bp overlap

PDX1 1 dataset

ChIP islet ERP001456.PDX1.islet 115 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 482 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 453 bp overlap

RBBP4 2 datasets

ChIP RH5 GSE155861.RBBP4.RH5 289 bp overlap

ChIP SCMC GSE155861.RBBP4.SCMC 374 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 342 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 334 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 259 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 251 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 275 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 419 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 445 bp overlap

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 177 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 333 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 374 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE67282.SOX2.hiPSC 218 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 283 bp overlap

TAL1::TCF3 1 dataset

Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

TCF7L1 2 datasets

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TRPS1 2 datasets

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

TWIST1 1 dataset

Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap

Tbx6 1 dataset

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

Tcf21 1 dataset

Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap

ZBTB18 1 dataset

Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap

ZFP42 1 dataset

Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap

ZNF300 1 dataset

ChIP HEK293T GSE78099.ZNF300.HEK293T 226 bp overlap

ZNF317 1 dataset

Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap

ZNF418 2 datasets

Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF75D 1 dataset

Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap

ZNF766 1 dataset

Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap

Zfp335 1 dataset

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap