chr6 : 149,550,921 – 149,551,908
987 bp 48 TFs 1 linked gene
This 987 bp open chromatin element is linked to PPIL4 and is bound by 48 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PPIL4 4.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:149,545,921 – 149,556,908
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
48 transcription factors
Source
Cell type
AR 3 datasets
ChIP MCF-7 ERP001226.AR.MCF-7 164 bp overlap
ChIP MCF-7 GSE48930.AR.MCF-7 197 bp overlap
ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 161 bp overlap
ARID4A 1 dataset
ChIP HepG2 ENCFF142DIE 240 bp overlap
BRD4 3 datasets
ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 199 bp overlap
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 148 bp overlap
ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 338 bp overlap
Bach1::Mafk 1 dataset
Motif DE_72h DE_72h-Bach1Mafk_MA0591.2 12 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap
CRY1 1 dataset
ChIP U2OS GSE44236.CRY1.U2OS 191 bp overlap
CTCF 2 datasets
ChIP GSC23 GSE139416.CTCF.GSC23 86 bp overlap
ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 94 bp overlap
EED 1 dataset
ChIP HepG2 ENCFF347CCA 173 bp overlap
EGR1 1 dataset
ChIP T-HESCs GSE141063.EGR1.T-HESCs 57 bp overlap
ESR1 71 datasets
ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 304 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 250 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 245 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 228 bp overlap
ChIP MCF-7 GSE68355.ESR1.MCF-7 237 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 164 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 183 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT_clone14 238 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_clone14 221 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 270 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 275 bp overlap
ChIP MCF-7_E2 GSE71276.ESR1.MCF-7_E2 182 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 243 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 111 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 237 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 249 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 248 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 263 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 178 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 209 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 160 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 290 bp overlap
ChIP MCF-7_LTED_E2 GSE86538.ESR1.MCF-7_LTED_E2 237 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 183 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 306 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 112 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 318 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 261 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 129 bp overlap
ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 124 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 157 bp overlap
ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 292 bp overlap
ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 59 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 228 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 196 bp overlap
ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 275 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 226 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 314 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 294 bp overlap
ChIP MCF-7_jc5853 GSE126004.ESR1.MCF-7_jc5853 307 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 302 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 301 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 200 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 302 bp overlap
ChIP MCF-7_shFbxo_E2_4OHT GSE119702.ESR1.MCF-7_shFbxo_E2_4OHT 140 bp overlap
ChIP MCF-7_shFbxo_OHT GSE119702.ESR1.MCF-7_shFbxo_OHT 140 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 273 bp overlap
ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 328 bp overlap
ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 193 bp overlap
ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 362 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 433 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 262 bp overlap
ChIP T-47D GSE74033.ESR1.T-47D 152 bp overlap
ChIP T-47D ENCSR000BJS.ESR1.T-47D 158 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 424 bp overlap
ChIP T-47D_E2 GSE125594.ESR1.T-47D_E2 319 bp overlap
ChIP T-47D_E2 GSE72249.ESR1.T-47D_E2 232 bp overlap
ChIP T-47D_JC4727 GSE126004.ESR1.T-47D_JC4727 246 bp overlap
ChIP T-47D_JC4731 GSE126004.ESR1.T-47D_JC4731 324 bp overlap
ChIP T-47D_JC4732 GSE126004.ESR1.T-47D_JC4732 280 bp overlap
ChIP T-47D_JC4733 GSE126004.ESR1.T-47D_JC4733 278 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 359 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 422 bp overlap
ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 426 bp overlap
ChIP T-47D_siCont-Veh GSE126004.ESR1.T-47D_siCont-Veh 231 bp overlap
ChIP T-47D_siFOXA1-IL6 GSE126004.ESR1.T-47D_siFOXA1-IL6 396 bp overlap
ChIP T-47D_siFOXA1-Veh GSE126004.ESR1.T-47D_siFOXA1-Veh 276 bp overlap
ChIP breast_tumor_Male_28 GSE104399.ESR1.breast_tumor_Male_28 285 bp overlap
ChIP breast_tumor_Male_5 GSE104399.ESR1.breast_tumor_Male_5 205 bp overlap
ChIP pleural-effusion GSE86538.ESR1.pleural-effusion 262 bp overlap
ChIP primary-breast-cancer_B2_DSG GSE114737.ESR1.primary-breast-cancer_B2_DSG 215 bp overlap
ESR1_D538G 1 dataset
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 250 bp overlap
ESR1_Y537C 1 dataset
ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 365 bp overlap
ESR1_Y537N 4 datasets
ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 189 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 249 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 238 bp overlap
ChIP MCF-7_talen GSE94493.ESR1_Y537N.MCF-7_talen 194 bp overlap
ESR1_Y537S 5 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 306 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 266 bp overlap
ChIP T-47D_E2 GSE94493.ESR1_Y537S.T-47D_E2 299 bp overlap
ChIP T-47D_dox GSE94493.ESR1_Y537S.T-47D_dox 334 bp overlap
ChIP T-47D_dox_E2 GSE94493.ESR1_Y537S.T-47D_dox_E2 334 bp overlap
EZH2 2 datasets
ChIP Pfeiffer GSE45982.EZH2.Pfeiffer 207 bp overlap
ChIP SU-DHL-6 GSE45982.EZH2.SU-DHL-6 160 bp overlap
FOXA1 1 dataset
ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 109 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 863 bp overlap
ChIP DE DE-FOXA2-2 850 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 257 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 833 bp overlap
ChIP DE DE-GATA4-2 928 bp overlap
GATA6 2 datasets
ChIP DE DE-GATA6-1 765 bp overlap
ChIP DE DE-GATA6-2 921 bp overlap
HIVEP1 1 dataset
ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 211 bp overlap
HMGXB4 2 datasets
ChIP HepG2 ENCFF032DND 399 bp overlap
ChIP HepG2 ENCFF032DND 68 bp overlap
KDM5B 1 dataset
ChIP HepG2 ENCFF706LUI 235 bp overlap
MED1 2 datasets
ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 232 bp overlap
ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 304 bp overlap
MNX1 1 dataset
ChIP HepG2 ENCFF938KYA 293 bp overlap
MYF6 1 dataset
Motif DE_72h DE_72h-MYF6_MA0667.1 10 bp overlap
NCOA2 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 222 bp overlap
NONO 1 dataset
ChIP HepG2 ENCFF361UQH 215 bp overlap
NOTCH1 1 dataset
ChIP HCC1599 GSE116871.NOTCH1.HCC1599 50 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 234 bp overlap
PGR 1 dataset
ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 183 bp overlap
PITX1 1 dataset
ChIP HepG2 ENCFF468QTQ 264 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 194 bp overlap
SMAD1 1 dataset
ChIP Hep-G2 ENCSR213QOZ.SMAD1.Hep-G2 171 bp overlap
STAT3 7 datasets
ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 309 bp overlap
ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 275 bp overlap
ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 190 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 463 bp overlap
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 426 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 328 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 294 bp overlap
Stat4 1 dataset
Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 291 bp overlap
TEAD4 1 dataset
ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 314 bp overlap
THAP9 1 dataset
ChIP HepG2 ENCFF687WSR 207 bp overlap
ZBTB7A 1 dataset
ChIP HepG2 ENCFF492YYQ 223 bp overlap
ZFY 1 dataset
ChIP HepG2 ENCFF106ELT 98 bp overlap
ZNF143 2 datasets
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 217 bp overlap
ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 277 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 65 bp overlap
ZNF317 1 dataset
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF407 1 dataset
ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 50 bp overlap
ZNF48 1 dataset
ChIP HepG2 ENCFF362CDQ 103 bp overlap
ZNF737 1 dataset
ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 84 bp overlap
ZSCAN31 1 dataset
ChIP HepG2 ENCFF066FRL 142 bp overlap
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