chr6 : 83,517,515 – 83,517,878

363 bp 63 TFs 1 linked gene

This 363 bp open chromatin element is linked to PRSS35 and is bound by 63 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PRSS35		5.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 245 bp overlap

ATF2 1 dataset

Motif DE_12h DE_12h-ATF2_MA1632.2 10 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 187 bp overlap

CBX1 1 dataset

ChIP Hep-G2 ENCSR819WZE.CBX1.Hep-G2 113 bp overlap

CTCF 19 datasets

ChIP A-549 ENCSR000DPF.CTCF.A-549 138 bp overlap

ChIP A-673 ENCSR611JJS.CTCF.A-673 248 bp overlap

ChIP A673 ENCFF123WOM 313 bp overlap

ChIP HeLa-Kyoto_PDS5-depleted GSE102884.CTCF.HeLa-Kyoto_PDS5-depleted 282 bp overlap

ChIP HeLa-Kyoto_WAPL-depleted GSE102884.CTCF.HeLa-Kyoto_WAPL-depleted 204 bp overlap

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.CTCF.HeLa-Kyoto_WAPL_PDS-depleted 254 bp overlap

ChIP HeLa-S3 ENCSR000DUB.CTCF.HeLa-S3 155 bp overlap

ChIP HeLa-S3_biotin GSE108869.CTCF.HeLa-S3_biotin 272 bp overlap

ChIP K-562 ENCSR000BPJ.CTCF.K-562 119 bp overlap

ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 240 bp overlap

ChIP PC-3 ENCSR359LOD.CTCF.PC-3 331 bp overlap

ChIP SLK_Ctrl GSE138105.CTCF.SLK_Ctrl 345 bp overlap

ChIP SLK_RAD21-KD GSE138105.CTCF.SLK_RAD21-KD 284 bp overlap

ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-000m 204 bp overlap

ChIP THP-1_Pam3csk-025m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-025m-Flavo-000m 220 bp overlap

ChIP THP-1_Pam3csk-150m-Flavo-030m GSE103477.CTCF.THP-1_Pam3csk-150m-Flavo-030m 203 bp overlap

ChIP THP-1_Pam3csk-180m-Flavo-060m GSE103477.CTCF.THP-1_Pam3csk-180m-Flavo-060m 233 bp overlap

ChIP THP-1_Pam3csk-360m-Flavo-240m GSE103477.CTCF.THP-1_Pam3csk-360m-Flavo-240m 188 bp overlap

ChIP bonchial_epithelial ENCSR000DXI.CTCF.bonchial_epithelial 110 bp overlap

CTCFL 1 dataset

ChIP FT282 GSE131931.CTCFL.FT282 150 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 51 bp overlap

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF3 1 dataset

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ETV5::DRGX 1 dataset

Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap

ETV6 1 dataset

ChIP WTC11 ENCFF812SCD 363 bp overlap

ETV7 1 dataset

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA1 2 datasets

ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 213 bp overlap

ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 148 bp overlap

FOXA2 1 dataset

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 214 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 343 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 341 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

JUN 3 datasets

ChIP ESC S24-ESC-d0-JUN-exp1 332 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 363 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 363 bp overlap

KLF4 2 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 117 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 74 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 287 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 327 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 199 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 210 bp overlap

ChIP hESC GSE18292.NANOG.hESC 180 bp overlap

NCOA1 1 dataset

ChIP MCF-7 ERP000901.NCOA1.MCF-7 161 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 251 bp overlap

NR4A1 1 dataset

Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_12h DE_12h-NR4A2_MA0160.3 8 bp overlap

ONECUT1 2 datasets

ChIP H9 ERP004206.ONECUT1.H9 50 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 154 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 131 bp overlap

POU5F1 3 datasets

ChIP BG03 GSE21614.POU5F1.BG03 164 bp overlap

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 222 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 272 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

RAD21 2 datasets

ChIP SLK_Ctrl GSE138105.RAD21.SLK_Ctrl 325 bp overlap

ChIP THP-1_Pam3csk-025m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-025m-Flavo-000m 182 bp overlap

RFX1 1 dataset

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 69 bp overlap

Runx1 1 dataset

Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 120 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 158 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 228 bp overlap

SMC3 2 datasets

ChIP HeLa-Kyoto_PDS5-depleted GSE102884.SMC3.HeLa-Kyoto_PDS5-depleted 363 bp overlap

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.SMC3.HeLa-Kyoto_WAPL_PDS-depleted 363 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

STAT3 1 dataset

ChIP HepaRG_sodium-oleate GSE89157.STAT3.HepaRG_sodium-oleate 263 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

Stat6 1 dataset

Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 334 bp overlap

TCF4 1 dataset

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 95 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

THRA 1 dataset

Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

ZBTB24 1 dataset

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 250 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF317 1 dataset

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

ZNF320 2 datasets

Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 236 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 136 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 239 bp overlap

ZNF675 1 dataset

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap