chr5 : 96,089,891 – 96,090,560

669 bp 62 TFs 4 linked genes

This 669 bp open chromatin element is linked to 4 target genes and is bound by 62 transcription factors.

Linked Genes

4 genes

Gene	Dist. to TSS	Distance	Link type
ENSG00000289337	81.9 kb	Distal	Multiome
ENSG00000251314	128.2 kb	Distal	Multiome+HiCAR
ELL2	128.4 kb	Distal	Multiome+HiCAR
GLRX	267.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

AR 1 dataset

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 151 bp overlap

ASCL1 1 dataset

Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap

BAP1 1 dataset

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 407 bp overlap

BRD4 8 datasets

ChIP DND41_E GSE54379.BRD4.DND41_E 669 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 640 bp overlap

ChIP SEM GSE83671.BRD4.SEM 205 bp overlap

ChIP SEM GSE83671.BRD4.SEM 58 bp overlap

ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 280 bp overlap

ChIP SUM159PT_DMSO_24h GSE87418.BRD4.SUM159PT_DMSO_24h 438 bp overlap

ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 308 bp overlap

ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 532 bp overlap

CASZ1 1 dataset

ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 414 bp overlap

CDK6 1 dataset

ChIP KB_IL GSE52469.CDK6.KB_IL 168 bp overlap

Crx 1 dataset

Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap

EBF1 2 datasets

ChIP MUTUL GSE75503.EBF1.MUTUL 115 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 53 bp overlap

ELF3 1 dataset

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 501 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 302 bp overlap

ChIP hESC GSE26097.EOMES.hESC 176 bp overlap

ERG 1 dataset

ChIP SEM GSE117864.ERG.SEM 153 bp overlap

EZH2 1 dataset

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 64 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA1 5 datasets

ChIP 22Rv1_CST GSE129951.FOXA1.22Rv1_CST 124 bp overlap

ChIP A-549 ENCSR000BPX.FOXA1.A-549 137 bp overlap

ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 669 bp overlap

ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 425 bp overlap

ChIP primary-breast-cancer_B1_DSG GSE114737.FOXA1.primary-breast-cancer_B1_DSG 419 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 669 bp overlap

ChIP DE DE-FOXA2-2 621 bp overlap

FOXP1 1 dataset

ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 202 bp overlap

GATA1 1 dataset

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 55 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 669 bp overlap

ChIP DE DE-GATA4-2 522 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 411 bp overlap

ChIP DE DE-GATA6-2 669 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 389 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 264 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 515 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 530 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 389 bp overlap

GSC 1 dataset

Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap

HSF1 1 dataset

ChIP MO91_27A_20UM GSE45852.HSF1.MO91_27A_20UM 117 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 221 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 201 bp overlap

Isl1 1 dataset

Motif DE_48h DE_48h-Isl1_MA1608.2 7 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 346 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap

MTA2 1 dataset

ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 153 bp overlap

MYOD1 2 datasets

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 407 bp overlap

ChIP SMS-CTR GSE137168.MYOD1.SMS-CTR 162 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 311 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 223 bp overlap

ChIP hESC GSE18292.NANOG.hESC 102 bp overlap

ChIP hESC GSE18292.NANOG.hESC 93 bp overlap

NEUROD1 2 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 377 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 266 bp overlap

NHLH2 1 dataset

Motif DE_48h DE_48h-NHLH2_MA1529.2 16 bp overlap

NR3C1 1 dataset

ChIP SUM159PT GSE152203.NR3C1.SUM159PT 290 bp overlap

OTX1 1 dataset

Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap

PATZ1 1 dataset

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

PITX1 1 dataset

Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap

Plagl1 1 dataset

Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap

RBPJ 1 dataset

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

RHOXF1 1 dataset

Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap

SIX2 1 dataset

Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 508 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 481 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 406 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 269 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

SNAI1 1 dataset

Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap

SNAI3 1 dataset

Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 497 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 258 bp overlap

SP5 1 dataset

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

SPIB 1 dataset

Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap

Spi1 1 dataset

Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 256 bp overlap

TCF12 1 dataset

Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap

TCF3 1 dataset

Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap

TCF4 1 dataset

Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap

TCF7L2 1 dataset

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

ZEB1 1 dataset

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF263 1 dataset

Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap

ZNF410 1 dataset

Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap

ZNF460 1 dataset

Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 146 bp overlap