chr4 : 154,738,957 – 154,739,452
495 bp 80 TFs 1 linked gene
This 495 bp open chromatin element is linked to LRAT and is bound by 80 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LRAT 4.5 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:154,733,957 – 154,744,452
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
80 transcription factors
Source
Cell type
BARX1 3 datasets
Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap
Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap
Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap
BCOR 2 datasets
ChIP WA01 GSE104690.BCOR.WA01 255 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 168 bp overlap
BRD9 1 dataset
ChIP MDA-MB-231_MGSK2801 GSE116879.BRD9.MDA-MB-231_MGSK2801 74 bp overlap
BSX 3 datasets
Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap
Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap
Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 340 bp overlap
CREBBP 1 dataset
ChIP keratinocyte GSE140991.CREBBP.keratinocyte 54 bp overlap
DLX1 3 datasets
Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap
Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap
Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap
DLX6 3 datasets
Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap
Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap
Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap
Dlx3 3 datasets
Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap
Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap
Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap
Dlx4 3 datasets
Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap
Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap
Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap
Dmrt1 1 dataset
Motif DE_12h DE_12h-Dmrt1_MA1603.2 9 bp overlap
EBF1 3 datasets
Motif DE_12h DE_12h-EBF1_MA0154.5 11 bp overlap
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 275 bp overlap
ERF::FOXO1 3 datasets
Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap
ETS1 1 dataset
ChIP hESC ENCSR534VHI.ETS1.hESC 179 bp overlap
ETV5::FOXI1 3 datasets
Motif DE_12h DE_12h-ETV5FOXI1_MA1946.2 12 bp overlap
Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap
Motif DE_60h DE_60h-ETV5FOXI1_MA1946.2 12 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2_phosphoT487 1 dataset
ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 389 bp overlap
Elf5 3 datasets
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
FOS 1 dataset
ChIP CFPAC-1 GSE119930.FOS.CFPAC-1 136 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 452 bp overlap
ChIP DE DE-FOXA2-2 424 bp overlap
FOXO1::ELF1 3 datasets
Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 3 datasets
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 3 datasets
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 132 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 318 bp overlap
GATA4 1 dataset
ChIP DE DE-GATA4-2 356 bp overlap
GATA6 1 dataset
ChIP DE DE-GATA6-2 404 bp overlap
GBX2 3 datasets
Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap
Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap
Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap
GLIS2 3 datasets
Motif DE_12h DE_12h-GLIS2_MA0736.1 14 bp overlap
Motif DE_48h DE_48h-GLIS2_MA0736.1 14 bp overlap
Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap
GLIS3 3 datasets
Motif DE_12h DE_12h-GLIS3_MA0737.1 14 bp overlap
Motif DE_48h DE_48h-GLIS3_MA0737.1 14 bp overlap
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
HESX1 3 datasets
Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap
Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap
Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap
HNF4A 2 datasets
Motif DE_12h DE_12h-HNF4A_MA0114.5 9 bp overlap
Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap
HNF4G 1 dataset
Motif DE_12h DE_12h-HNF4G_MA0484.3 9 bp overlap
HOXA7 3 datasets
Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap
Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap
Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap
IKZF2 3 datasets
Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Ikzf3 3 datasets
Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 250 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 414 bp overlap
LBX2 3 datasets
Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap
Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap
Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap
LHX2 3 datasets
Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap
Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap
Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap
MEIS1 1 dataset
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MSX1 3 datasets
Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap
Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap
Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap
MSX2 3 datasets
Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap
Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap
Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap
Msx3 3 datasets
Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap
Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap
Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap
NANOG 9 datasets
ChIP GM23338 ENCFF065NZG 311 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 170 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 438 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 272 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 456 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 378 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 399 bp overlap
ChIP hESC GSE18292.NANOG.hESC 109 bp overlap
ChIP hESC GSE18292.NANOG.hESC 96 bp overlap
NFIB 3 datasets
Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap
NFYB 2 datasets
Motif DE_12h DE_12h-NFYB_MA0502.3 9 bp overlap
Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap
NIPBL 1 dataset
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 266 bp overlap
NR1I3 1 dataset
Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap
Nobox 3 datasets
Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap
Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap
Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap
Nr2f6 1 dataset
Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap
POU5F1 1 dataset
ChIP hESC ENCSR264RJX.POU5F1.hESC 140 bp overlap
PPARG 3 datasets
Motif DE_12h DE_12h-PPARG_MA0066.2 19 bp overlap
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
Pparg::Rxra 1 dataset
Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap
RAX 3 datasets
Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap
Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap
Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap
RNF2 3 datasets
ChIP WA09 GSE105028.RNF2.WA09 213 bp overlap
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 264 bp overlap
ChIP fibroblast GSE139053.RNF2.fibroblast 145 bp overlap
RXRG 1 dataset
Motif DE_12h DE_12h-RXRG_MA0856.1 14 bp overlap
Rarg 3 datasets
Motif DE_12h DE_12h-Rarg_MA0860.1 17 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap
Rxra 1 dataset
Motif DE_12h DE_12h-Rxra_MA0512.2 14 bp overlap
SMAD2 2 datasets
ChIP hESC GSE29422.SMAD2.hESC 116 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 192 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 327 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 451 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 246 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 360 bp overlap
SMAD3 2 datasets
ChIP endoderm GSE29422.SMAD3.endoderm 168 bp overlap
ChIP hESC GSE29422.SMAD3.hESC 214 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 265 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 213 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 215 bp overlap
SOX10 1 dataset
Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap
SOX15 1 dataset
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
SOX2 2 datasets
ChIP hESC GSE18292.SOX2.hESC 108 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 186 bp overlap
SP4 3 datasets
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SS18 1 dataset
ChIP Aska-SS GSE108025.SS18.Aska-SS 92 bp overlap
Sox11 1 dataset
Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap
Sox6 1 dataset
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
TBX5 2 datasets
ChIP G296S_4 GSE85628.TBX5.G296S_4 110 bp overlap
ChIP G296S_4 GSE85628.TBX5.G296S_4 172 bp overlap
TCF7L2 1 dataset
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
ZNF184 1 dataset
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
ZNF263 3 datasets
Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
ZNF317 1 dataset
Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap
ZNF354A 1 dataset
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Huangfu Lab · Publications · Resources · Contact