chr4:52,716,767–52,717,011

chr4 : 52,716,767 – 52,717,011

244 bp 50 TFs 5 linked genes

This 244 bp open chromatin element is linked to 5 target genes and is bound by 50 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SNORA26		3.5 kb	Proximal	Proximity
MIR4449		4.1 kb	Proximal	Proximity
DANCR		4.3 kb	Proximal	Proximity
LINC01618		4.4 kb	Proximal	Proximity
ENSG00000286161		5.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

AGO1 3 datasets

ChIP K-562 GSE120104.AGO1.K-562 70 bp overlap

ChIP K562 ENCFF741BCI 244 bp overlap

ChIP K562 ENCFF741BCI 244 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 125 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 134 bp overlap

BRD4 3 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 157 bp overlap

ChIP MOLM-14_DMSO GSE65138.BRD4.MOLM-14_DMSO 92 bp overlap

ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 201 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 244 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 244 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 244 bp overlap

CTCF 3 datasets

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 229 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 218 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 244 bp overlap

EMX1 2 datasets

ChIP WTC11 ENCFF692RZJ 116 bp overlap

ChIP WTC11 ENCFF692RZJ 244 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 158 bp overlap

ChIP WTC11 ENCFF011YUL 141 bp overlap

ESR1_pS118 2 datasets

ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 244 bp overlap

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 244 bp overlap

ESRRA 1 dataset

Motif ES_0h ES_0h-ESRRA_MA0592.4 9 bp overlap

ETS1 2 datasets

ChIP HEY-A8 GSE101832.ETS1.HEY-A8 240 bp overlap

ChIP OVCAR-8 GSE101832.ETS1.OVCAR-8 244 bp overlap

EWSR1 1 dataset

ChIP K-562 ENCSR142YYA.EWSR1.K-562 167 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 244 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 244 bp overlap

ChIP DE DE-FOXA2-2 234 bp overlap

GATA4 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 139 bp overlap

ChIP DE DE-GATA4-1 244 bp overlap

ChIP DE DE-GATA4-2 223 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 238 bp overlap

ChIP DE DE-GATA6-2 215 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 215 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 122 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 244 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 244 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 244 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 244 bp overlap

HOXB13 1 dataset

ChIP G-401 GSE65381.HOXB13.G-401 244 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 116 bp overlap

MEF2D 3 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 244 bp overlap

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 244 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 244 bp overlap

ChIP GM12878 ENCSR000BRH.MTA3.GM12878 93 bp overlap

MYBL2 2 datasets

ChIP A-673 GSE119971.MYBL2.A-673 244 bp overlap

ChIP MCF-10A_ctrl GSE115787.MYBL2.MCF-10A_ctrl 138 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 244 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 244 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 163 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 159 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 180 bp overlap

NR5A1 1 dataset

Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 244 bp overlap

Nr5A2 1 dataset

Motif ES_0h ES_0h-Nr5A2_MA0505.3 9 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 244 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 244 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 222 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 182 bp overlap

POLR2A 23 datasets

ChIP GM12878 ENCFF263VRI 93 bp overlap

ChIP GM12878 ENCFF263VRI 244 bp overlap

ChIP GM12892 ENCFF245LYF 128 bp overlap

ChIP GM18505 ENCFF311CYB 154 bp overlap

ChIP GM19193 ENCFF599VTO 63 bp overlap

ChIP GM19193 ENCFF599VTO 244 bp overlap

ChIP GM23338 ENCFF450WCS 244 bp overlap

ChIP H1 ENCFF566JSR 227 bp overlap

ChIP H1 ENCFF770YBQ 153 bp overlap

ChIP H1 ENCFF833NJP 158 bp overlap

ChIP HepG2 ENCFF350RIU 218 bp overlap

ChIP K562 ENCFF137JSF 88 bp overlap

ChIP K562 ENCFF137JSF 244 bp overlap

ChIP K562 ENCFF214YGX 158 bp overlap

ChIP K562 ENCFF215CWW 244 bp overlap

ChIP K562 ENCFF262YXJ 202 bp overlap

ChIP PFSK-1 ENCFF576NIT 71 bp overlap

ChIP PFSK-1 ENCFF576NIT 244 bp overlap

ChIP PFSK-1 ENCFF576NIT 141 bp overlap

ChIP SK-N-MC ENCFF088IVG 244 bp overlap

ChIP SK-N-MC ENCFF088IVG 161 bp overlap

ChIP endothelial cell of umbilical vein ENCFF303XUJ 79 bp overlap

ChIP endothelial cell of umbilical vein ENCFF467WJF 244 bp overlap

POLR2G 1 dataset

ChIP HepG2 ENCFF508UTS 244 bp overlap

PTBP1 1 dataset

ChIP K-562 GSE120104.PTBP1.K-562 144 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 81 bp overlap

RBFOX2 1 dataset

ChIP K562 ENCFF196WTG 244 bp overlap

RBM22 2 datasets

ChIP HepG2 ENCFF292RVQ 207 bp overlap

ChIP HepG2 ENCFF561IAJ 172 bp overlap

ChIP U2OS_10Gy_2h_recovery GSE109996.RELA.U2OS_10Gy_2h_recovery 181 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 244 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 65 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 90 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 176 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 244 bp overlap

SMAD3 2 datasets

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 111 bp overlap

ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 105 bp overlap

SMAD5 2 datasets

ChIP K-562 ENCSR000FCD.SMAD5.K-562 140 bp overlap

ChIP K562 ENCFF941FJJ 244 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 244 bp overlap

SUPT5H 9 datasets

ChIP DLD-1_NELFE-AID GSE144786.SUPT5H.DLD-1_NELFE-AID 229 bp overlap

ChIP DLD-1_NELFE-AID_treated GSE144786.SUPT5H.DLD-1_NELFE-AID_treated 53 bp overlap

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 244 bp overlap

ChIP HCT-116_DMSO_pSer666 GSE138548.SUPT5H.HCT-116_DMSO_pSer666 146 bp overlap

ChIP HCT-116_DMSO_pThr806 GSE138548.SUPT5H.HCT-116_DMSO_pThr806 204 bp overlap

ChIP K562 ENCFF902PAW 230 bp overlap

ChIP U2OS_DMSO GSE115365.SUPT5H.U2OS_DMSO 244 bp overlap

ChIP U2OS_siMYC GSE115365.SUPT5H.U2OS_siMYC 185 bp overlap

ChIP U2OS_siMYC_ON GSE115365.SUPT5H.U2OS_siMYC_ON 244 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 244 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 143 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 220 bp overlap

ZNF317 1 dataset

Motif ES_0h ES_0h-ZNF317_MA1593.2 8 bp overlap

ZNF354C 1 dataset

Motif ES_0h ES_0h-ZNF354C_MA0130.1 6 bp overlap

Motif ES_0h ES_0h-ZNF8_MA1718.1 20 bp overlap