chr4 : 16,617,871 – 16,618,435
564 bp 59 TFs 1 linked gene
This 564 bp open chromatin element is linked to LDB2 and is bound by 59 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LDB2 280.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:16,612,871 – 16,623,435
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
59 transcription factors
Source
Cell type
ASCL1 2 datasets
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap
ATF4 1 dataset
Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap
BRF1 1 dataset
ChIP H9_Activin GSE94418.BRF1.H9_Activin 148 bp overlap
CDK8 1 dataset
ChIP myometrium_PT916 GSE128230.CDK8.myometrium_PT916 82 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 253 bp overlap
FIGLA 5 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA1 1 dataset
ChIP HEK293_r261g_TFS GSE123618.FOXA1.HEK293_r261g_TFS 112 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 501 bp overlap
ChIP DE DE-FOXA2-2 562 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 479 bp overlap
ChIP DE DE-GATA4-2 557 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 489 bp overlap
ChIP DE DE-GATA6-2 468 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 367 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 313 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 341 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 333 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 420 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 432 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 507 bp overlap
GRHL2 2 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
IRF2 2 datasets
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
IRF8 1 dataset
ChIP THP-1 GSE123872.IRF8.THP-1 55 bp overlap
ISL2 2 datasets
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Irf1 2 datasets
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
KLF5 2 datasets
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
KLF9 2 datasets
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap
MEIS1 2 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MGA 2 datasets
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MYF6 2 datasets
Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
MZF1 1 dataset
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Mecom 2 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NHLH2 2 datasets
Motif DE_48h DE_48h-NHLH2_MA1529.2 16 bp overlap
Motif DE_60h DE_60h-NHLH2_MA1529.2 16 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 179 bp overlap
PHF19 1 dataset
ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 273 bp overlap
PRDM1 1 dataset
ChIP fetal_testis GSE100639.PRDM1.fetal_testis 189 bp overlap
Ptf1A 1 dataset
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
RBPJ 2 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
REST 2 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
Rarb 1 dataset
Motif DE_48h DE_48h-Rarb_MA0858.1 17 bp overlap
Rhox11 1 dataset
Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 302 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 564 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 445 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 445 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 362 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 321 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 441 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 411 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 160 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 202 bp overlap
SNAI1 2 datasets
Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap
Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 455 bp overlap
SP1 2 datasets
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap
SP4 2 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
SP5 2 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
TBX1 2 datasets
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 2 datasets
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 2 datasets
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX20 2 datasets
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX4 2 datasets
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TCF12 2 datasets
Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap
Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap
TCF3 2 datasets
Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap
Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap
TCF4 2 datasets
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
TFAP4::FLI1 2 datasets
Motif DE_48h DE_48h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap
Tbx6 1 dataset
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Yy1 2 datasets
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap
ZEB1 5 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZNF263 2 datasets
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
ZNF460 2 datasets
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF75D 1 dataset
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Zfp809 2 datasets
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Zfx 2 datasets
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap
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