chr1 : 47,307,736 – 47,308,358

622 bp 63 TFs 3 linked genes

This 622 bp open chromatin element is linked to STIL, CMPK1, and CYP4A22-AS1 and is bound by 63 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
STIL	5.8 kb	Proximal	Proximity
CMPK1	25.7 kb	Distal	Multiome
CYP4A22-AS1	128.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_24h DE_24h-ARNTHIF1A_MA0259.2 5 bp overlap

Arid3a 2 datasets

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap

CDX1 1 dataset

Motif DE_24h DE_24h-CDX1_MA0878.3 10 bp overlap

CTCF 1 dataset

ChIP endodermal cell ENCFF471YCZ 337 bp overlap

E2F6 1 dataset

Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap

E2F7 1 dataset

Motif DE_24h DE_24h-E2F7_MA0758.1 14 bp overlap

EOMES 1 dataset

Motif DE_24h DE_24h-EOMES_MA0800.2 9 bp overlap

ETV2 1 dataset

Motif DE_24h DE_24h-ETV2_MA0762.2 9 bp overlap

ETV5::FOXO1 2 datasets

Motif DE_12h DE_12h-ETV5FOXO1_MA1947.2 10 bp overlap

Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap

FEZF2 1 dataset

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 277 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 521 bp overlap

ChIP DE DE-GATA4-2 522 bp overlap

Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 488 bp overlap

ChIP DE DE-GATA6-2 589 bp overlap

Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 617 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 615 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 622 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 531 bp overlap

GLI3 1 dataset

Motif DE_24h DE_24h-GLI3_MA1491.3 15 bp overlap

Gata3 1 dataset

Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap

HIC2 1 dataset

Motif DE_24h DE_24h-HIC2_MA0738.2 6 bp overlap

HOXB4 2 datasets

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap

HOXD3 2 datasets

Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap

Motif DE_24h DE_24h-HOXD3_MA0912.2 8 bp overlap

HOXD4 2 datasets

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap

Hmga1 2 datasets

Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap

Motif DE_24h DE_24h-Hmga1_MA2124.1 8 bp overlap

Hnf1A 1 dataset

Motif DE_24h DE_24h-Hnf1A_MA1991.2 10 bp overlap

Hoxa13 1 dataset

Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap

IKZF1 1 dataset

Motif DE_24h DE_24h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap

IRF7 2 datasets

Motif DE_12h DE_12h-IRF7_MA0772.2 13 bp overlap

Motif DE_24h DE_24h-IRF7_MA0772.2 13 bp overlap

JUN 2 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 263 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 378 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

MEIS3 2 datasets

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

Motif DE_24h DE_24h-MEIS3_MA0775.2 7 bp overlap

MGA 1 dataset

Motif DE_24h DE_24h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_24h DE_24h-MGAEVX1_MA1960.2 11 bp overlap

POU1F1 2 datasets

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 569 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 458 bp overlap

POU6F1 2 datasets

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

Motif DE_24h DE_24h-POU6F1_MA1549.2 7 bp overlap

POU6F2 2 datasets

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

Motif DE_24h DE_24h-POU6F2_MA0793.2 9 bp overlap

RBPJ 1 dataset

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

REL 1 dataset

Motif DE_24h DE_24h-REL_MA0101.1 10 bp overlap

RELA 1 dataset

Motif DE_24h DE_24h-RELA_MA0107.1 10 bp overlap

RUNX3 2 datasets

Motif DE_12h DE_12h-RUNX3_MA0684.3 8 bp overlap

Motif DE_24h DE_24h-RUNX3_MA0684.3 8 bp overlap

SATB1 2 datasets

Motif DE_24h DE_24h-SATB1_MA1963.2 7 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 147 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 200 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 622 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 622 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 587 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 622 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 547 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S10-DE-d1-BAF155-exp1 267 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 400 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 492 bp overlap

SOX21 4 datasets

Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap

Motif DE_24h DE_24h-SOX21_MA0866.1 15 bp overlap

SREBF1 1 dataset

Motif DE_24h DE_24h-SREBF1_MA0829.3 10 bp overlap

Six3 1 dataset

Motif DE_24h DE_24h-Six3_MA0631.2 11 bp overlap

Sox1 2 datasets

Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap

Motif DE_24h DE_24h-Sox1_MA0870.1 15 bp overlap

Spi1 1 dataset

Motif DE_24h DE_24h-Spi1_MA0080.7 13 bp overlap

TBX18 1 dataset

Motif DE_24h DE_24h-TBX18_MA1565.2 9 bp overlap

TBX20 2 datasets

Motif DE_24h DE_24h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_24h DE_24h-TBX21_MA0690.3 10 bp overlap

TBX4 1 dataset

Motif DE_24h DE_24h-TBX4_MA0806.1 8 bp overlap

TBXT 1 dataset

Motif DE_24h DE_24h-TBXT_MA0009.2 16 bp overlap

TFCP2 1 dataset

Motif DE_24h DE_24h-TFCP2_MA1968.2 9 bp overlap

TRPS1 1 dataset

Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap

Tbx6 1 dataset

Motif DE_24h DE_24h-Tbx6_MA1567.3 9 bp overlap

ZNF257 1 dataset

Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ZNF507 1 dataset

ChIP K562 ENCFF577IRE 104 bp overlap