chr2 : 177,681,932 – 177,682,409
477 bp 64 TFs 3 linked genes
This 477 bp open chromatin element is linked to AGPS, ENSG00000213963, and NFE2L2 and is bound by 64 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
AGPS 289.3 kb Distal Multiome
ENSG00000213963 289.4 kb Distal Multiome
NFE2L2 289.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:177,676,932 – 177,687,409
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
64 transcription factors
Source
Cell type
ARID1B 1 dataset
ChIP K-562 ENCSR822CCM.ARID1B.K-562 223 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 258 bp overlap
ChIP K562 ENCFF673OEZ 411 bp overlap
CUX1 3 datasets
Motif DE_12h DE_12h-CUX1_MA0754.3 9 bp overlap
Motif DE_24h DE_24h-CUX1_MA0754.3 9 bp overlap
ChIP K562 ENCFF057AIX 345 bp overlap
CUX2 2 datasets
Motif DE_12h DE_12h-CUX2_MA0755.2 9 bp overlap
Motif DE_24h DE_24h-CUX2_MA0755.2 9 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 405 bp overlap
ChIP DE DE-FOXA2-2 335 bp overlap
FOXE1 4 datasets
Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap
Motif DE_24h DE_24h-FOXE1_MA1487.3 12 bp overlap
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
GATA1::TAL1 2 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 3 datasets
Motif DE_24h DE_24h-GATA2_MA0036.4 7 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 450 bp overlap
ChIP DE DE-GATA4-2 477 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 261 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 252 bp overlap
GATA5 5 datasets
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 16 datasets
ChIP DE DE-GATA6-1 405 bp overlap
ChIP DE DE-GATA6-2 477 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 477 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 477 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 465 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 390 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 477 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 434 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 296 bp overlap
ChIP foregut GSE117136.GATA6.foregut 271 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 235 bp overlap
GATAD2B 1 dataset
ChIP K562 ENCFF696VMK 358 bp overlap
Gata3 5 datasets
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HAND2 4 datasets
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
HDAC1 1 dataset
ChIP K562 ENCFF968WBH 443 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR197ALX.HDGF.K-562 206 bp overlap
HSF2 2 datasets
Motif DE_36h DE_36h-HSF2_MA0770.1 13 bp overlap
Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap
Hnf1A 1 dataset
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
IKZF1 3 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 386 bp overlap
ChIP K562 ENCFF348IBL 197 bp overlap
ChIP K562 ENCFF771OHZ 421 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 422 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 276 bp overlap
MEIS2 2 datasets
ChIP K-562 ENCSR851BNE.MEIS2.K-562 235 bp overlap
ChIP K562 ENCFF320GSD 301 bp overlap
MYBL2 1 dataset
ChIP K562 ENCFF299JBQ 397 bp overlap
Mecom 3 datasets
Motif DE_24h DE_24h-Mecom_MA0029.2 11 bp overlap
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 333 bp overlap
NFIA 2 datasets
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
NFIC 2 datasets
Motif DE_36h DE_36h-NFIC_MA0161.3 7 bp overlap
Motif DE_48h DE_48h-NFIC_MA0161.3 7 bp overlap
NFIX 2 datasets
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
ONECUT1 4 datasets
Motif DE_12h DE_12h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_24h DE_24h-ONECUT1_MA0679.3 9 bp overlap
ChIP H9 ERP004206.ONECUT1.H9 278 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 412 bp overlap
ONECUT2 3 datasets
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 236 bp overlap
Motif DE_12h DE_12h-ONECUT2_MA0756.3 8 bp overlap
Motif DE_24h DE_24h-ONECUT2_MA0756.3 8 bp overlap
PBX2 2 datasets
ChIP K-562 ENCSR263DFP.PBX2.K-562 293 bp overlap
ChIP K562 ENCFF286KMN 417 bp overlap
PKNOX1 4 datasets
ChIP HEK293T ENCFF174WDB 351 bp overlap
ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 240 bp overlap
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 348 bp overlap
ChIP K562 ENCFF236IUS 311 bp overlap
POU1F1 4 datasets
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap
Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
POU2F1 4 datasets
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap
Motif DE_36h DE_36h-POU2F1_MA0785.2 9 bp overlap
Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 4 datasets
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 4 datasets
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap
Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
POU2F3 4 datasets
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap
Motif DE_36h DE_36h-POU2F3_MA0627.3 9 bp overlap
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
POU3F1 4 datasets
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap
Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
POU3F2 4 datasets
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap
Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
POU3F3 4 datasets
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap
Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
POU3F4 4 datasets
Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap
Motif DE_24h DE_24h-POU3F4_MA0789.1 9 bp overlap
Motif DE_36h DE_36h-POU3F4_MA0789.1 9 bp overlap
Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap
POU5F1 3 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 454 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 380 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 296 bp overlap
POU5F1B 4 datasets
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_36h DE_36h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 410 bp overlap
Pou5f1::Sox2 4 datasets
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm15 2 datasets
Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap
Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap
RARA 1 dataset
Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap
SMAD2 4 datasets
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 331 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 415 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 477 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 414 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 356 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 357 bp overlap
SMARCC1 2 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 281 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 120 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 439 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 327 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 247 bp overlap
SOX21 4 datasets
Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap
Motif DE_24h DE_24h-SOX21_MA0866.1 15 bp overlap
Motif DE_36h DE_36h-SOX21_MA0866.1 15 bp overlap
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
SOX6 2 datasets
ChIP K-562 ENCSR788RSW.SOX6.K-562 223 bp overlap
ChIP K562 ENCFF059YCJ 437 bp overlap
Sox1 4 datasets
Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap
Motif DE_24h DE_24h-Sox1_MA0870.1 15 bp overlap
Motif DE_36h DE_36h-Sox1_MA0870.1 15 bp overlap
Motif DE_48h DE_48h-Sox1_MA0870.1 15 bp overlap
TBX21 2 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
TBX3 2 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
TCF7L2 1 dataset
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 5 datasets
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZBTB26 2 datasets
Motif DE_36h DE_36h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap
ZEB2 2 datasets
ChIP K-562 ENCSR004GKA.ZEB2.K-562 213 bp overlap
ChIP K562 ENCFF795CMH 411 bp overlap
ZNF354A 2 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
ZNF766 2 datasets
Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
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