chr2 : 65,558,091 – 65,558,575
484 bp 55 TFs 1 linked gene
This 484 bp open chromatin element is linked to SPRED2 and is bound by 55 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SPRED2 125.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:65,553,091 – 65,563,575
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
55 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 484 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 243 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 135 bp overlap
BAP1 1 dataset
ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 81 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 216 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 410 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 194 bp overlap
BRD4 2 datasets
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 249 bp overlap
ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 215 bp overlap
CEBPB 2 datasets
ChIP H1 ENCFF871PTR 261 bp overlap
ChIP WA01 ENCSR000EBV.CEBPB.WA01 223 bp overlap
CREB1 5 datasets
ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 93 bp overlap
ChIP MCF-7 ENCFF341ZEM 59 bp overlap
ChIP MCF-7 ENCFF867SAS 55 bp overlap
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 83 bp overlap
ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 100 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 241 bp overlap
EBF1 1 dataset
ChIP MUTUL GSE75503.EBF1.MUTUL 125 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 314 bp overlap
EP300 1 dataset
ChIP WA01 ENCSR000BKK.EP300.WA01 199 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 368 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 187 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 436 bp overlap
ChIP DE DE-GATA4-2 484 bp overlap
ChIP foregut GSE117136.GATA4.foregut 290 bp overlap
GATA5 1 dataset
Motif ES_0h ES_0h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 371 bp overlap
ChIP DE DE-GATA6-2 484 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 297 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 280 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 259 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 456 bp overlap
Motif ES_0h ES_0h-GATA6_MA1104.3 8 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 356 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 360 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 280 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 263 bp overlap
GFI1 1 dataset
Motif ES_0h ES_0h-GFI1_MA0038.3 11 bp overlap
Gata3 1 dataset
Motif ES_0h ES_0h-Gata3_MA0037.5 8 bp overlap
Gfi1B 1 dataset
Motif ES_0h ES_0h-Gfi1B_MA0483.2 10 bp overlap
HOXC6 1 dataset
ChIP 22Rv1 GSE129951.HOXC6.22Rv1 65 bp overlap
JUN 5 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 484 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 347 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 379 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 441 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 137 bp overlap
KLF4 3 datasets
ChIP HAP1 GSE130417.KLF4.HAP1 415 bp overlap
ChIP WA09 GSE105028.KLF4.WA09 252 bp overlap
ChIP hiPSC GSE56567.KLF4.hiPSC 309 bp overlap
NANOG 7 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 484 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 284 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 222 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 484 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 459 bp overlap
ChIP hESC GSE20650.NANOG.hESC 186 bp overlap
ChIP hESC GSE18292.NANOG.hESC 168 bp overlap
NIPBL 1 dataset
ChIP WA09 GSE105028.NIPBL.WA09 469 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU2F3 1 dataset
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU5F1 11 datasets
Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 484 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 481 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 484 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 437 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 365 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 484 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 484 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 360 bp overlap
ChIP hiPSC GSE149017.POU5F1.hiPSC 246 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 407 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
PRDM14 1 dataset
ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 371 bp overlap
Pou5f1::Sox2 1 dataset
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
RAD21 3 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 329 bp overlap
ChIP HAP1 GSE126634.RAD21.HAP1 237 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 484 bp overlap
RNF2 2 datasets
ChIP WA09 GSE105028.RNF2.WA09 363 bp overlap
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 386 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 472 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 310 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 304 bp overlap
SMAD3 1 dataset
ChIP BG03 GSE21614.SMAD3.BG03 222 bp overlap
SMARCA4 3 datasets
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 248 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 453 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 484 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 239 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 432 bp overlap
SMARCC1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 411 bp overlap
SMC1 1 dataset
ChIP HAP1_WaplKO-33_SCC4KO GSE94992.SMC1.HAP1_WaplKO-33_SCC4KO 247 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 226 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 451 bp overlap
SOX2 6 datasets
ChIP H9 GSE46837.SOX2.H9 429 bp overlap
ChIP hESC GSE18292.SOX2.hESC 133 bp overlap
ChIP hESC GSE69479.SOX2.hESC 260 bp overlap
ChIP hESC GSE18292.SOX2.hESC 95 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 454 bp overlap
ChIP hiPSC_3s2 GSE81899.SOX2.hiPSC_3s2 395 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 283 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 226 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 411 bp overlap
TFAP2C 2 datasets
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 484 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 484 bp overlap
TRPS1 1 dataset
Motif ES_0h ES_0h-TRPS1_MA1970.2 8 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 147 bp overlap
ZNF143 2 datasets
ChIP WA09 GSE105028.ZNF143.WA09 171 bp overlap
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 187 bp overlap
ZNF398 2 datasets
ChIP BG01V GSE133630.ZNF398.BG01V 211 bp overlap
ChIP H9 GSE133630.ZNF398.H9 203 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 76 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 267 bp overlap
ZNF513 2 datasets
ChIP HEK293 ENCFF457TCC 95 bp overlap
ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 161 bp overlap
ZNF582 1 dataset
Motif ES_0h ES_0h-ZNF582_MA1983.2 19 bp overlap
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