chr21 : 36,434,206 – 36,435,196
990 bp 69 TFs 5 linked genes
This 990 bp open chromatin element is linked to 5 target genes and is bound by 69 transcription factors.
Linked Genes
5 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LNCTSI 3.8 kb Proximal Proximity
ENSG00000289221 4.1 kb Proximal Proximity
CHAF1B 49.3 kb Distal Multiome
MORC3 114.5 kb Distal Multiome
DOP1B 277.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:36,429,206 – 36,440,196
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
69 transcription factors
Source
Cell type
AR 1 dataset
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 351 bp overlap
ARID1A 3 datasets
ChIP RMG-I GSE104545.ARID1A.RMG-I 618 bp overlap
ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 516 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.ARID1A.endometrial-epithelial-cells_KO 259 bp overlap
Ahr::Arnt 3 datasets
Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BCL3 1 dataset
ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 175 bp overlap
BRD2 1 dataset
ChIP HCC1806_BAZ2BsiRNA GSE116879.BRD2.HCC1806_BAZ2BsiRNA 251 bp overlap
EOMES 4 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 907 bp overlap
ETV5::FOXO1 3 datasets
Motif DE_36h DE_36h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap
ETV6 1 dataset
ChIP Reh_pCCL-ETV6-HA GSE102785.ETV6.Reh_pCCL-ETV6-HA 333 bp overlap
FIGLA 1 dataset
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
FLI1::FOXI1 3 datasets
Motif DE_36h DE_36h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA1 7 datasets
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 418 bp overlap
ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 390 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 359 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 454 bp overlap
ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 761 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 317 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 446 bp overlap
FOXA2 5 datasets
ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 346 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 409 bp overlap
ChIP DE DE-FOXA2-1 961 bp overlap
ChIP DE DE-FOXA2-2 964 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 295 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 795 bp overlap
ChIP DE DE-GATA4-2 919 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 742 bp overlap
ChIP DE DE-GATA6-2 848 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 738 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 808 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 710 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 799 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 858 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 754 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 572 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 69 bp overlap
IKZF1 2 datasets
ChIP GM12878 ENCFF824TGK 301 bp overlap
ChIP GM12878 ENCFF824TGK 511 bp overlap
IRF1 6 datasets
ChIP K-562 ENCSR854MCV.IRF1.K-562 498 bp overlap
ChIP K-562_EPZ GSE129380.IRF1.K-562_EPZ 187 bp overlap
ChIP K562 ENCFF277KTJ 390 bp overlap
ChIP K562 ENCFF277KTJ 561 bp overlap
ChIP PDAC GSE64557.IRF1.PDAC 310 bp overlap
ChIP PDAC GSE64557.IRF1.PDAC 366 bp overlap
IRF2 1 dataset
ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 296 bp overlap
JUN 5 datasets
ChIP 786-O GSE86092.JUN.786-O 179 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 287 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 285 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 733 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 313 bp overlap
KLF4 1 dataset
ChIP keratinocyte_diff GSE57702.KLF4.keratinocyte_diff 147 bp overlap
MAML1 1 dataset
ChIP SCC_4h GSE156486.MAML1.SCC_4h 193 bp overlap
MAX 2 datasets
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 214 bp overlap
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 288 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MSANTD3 3 datasets
Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MTF1 3 datasets
Motif DE_36h DE_36h-MTF1_MA0863.1 14 bp overlap
Motif DE_48h DE_48h-MTF1_MA0863.1 14 bp overlap
Motif DE_72h DE_72h-MTF1_MA0863.1 14 bp overlap
NFKB1 1 dataset
ChIP L1236 GSE63736.NFKB1.L1236 619 bp overlap
NFKB2 1 dataset
ChIP L1236 GSE63736.NFKB2.L1236 566 bp overlap
NKX2-5 1 dataset
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 185 bp overlap
NOTCH1 1 dataset
ChIP pulmonary-artery_endothelial-cell_siPFKFB3 GSE89786.NOTCH1.pulmonary-artery_endothelial-cell_siPFKFB3 173 bp overlap
ONECUT1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 337 bp overlap
ONECUT2 1 dataset
ChIP A-549 GSE102599.ONECUT2.A-549 217 bp overlap
PAX1 3 datasets
Motif DE_36h DE_36h-PAX1_MA0779.2 16 bp overlap
Motif DE_48h DE_48h-PAX1_MA0779.2 16 bp overlap
Motif DE_72h DE_72h-PAX1_MA0779.2 16 bp overlap
PAX2 3 datasets
Motif DE_36h DE_36h-PAX2_MA0067.3 16 bp overlap
Motif DE_48h DE_48h-PAX2_MA0067.3 16 bp overlap
Motif DE_72h DE_72h-PAX2_MA0067.3 16 bp overlap
PAX8 3 datasets
Motif DE_36h DE_36h-PAX8_MA2094.1 16 bp overlap
Motif DE_48h DE_48h-PAX8_MA2094.1 16 bp overlap
Motif DE_72h DE_72h-PAX8_MA2094.1 16 bp overlap
PAX9 3 datasets
Motif DE_36h DE_36h-PAX9_MA0781.2 16 bp overlap
Motif DE_48h DE_48h-PAX9_MA0781.2 16 bp overlap
Motif DE_72h DE_72h-PAX9_MA0781.2 16 bp overlap
PBX3 3 datasets
Motif DE_36h DE_36h-PBX3_MA1114.2 11 bp overlap
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap
PHIP 1 dataset
ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 319 bp overlap
PKNOX1 3 datasets
Motif DE_36h DE_36h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_72h DE_72h-PKNOX1_MA0782.3 10 bp overlap
POLR2A 5 datasets
ChIP endothelial cell of umbilical vein ENCFF091YHT 376 bp overlap
ChIP endothelial cell of umbilical vein ENCFF091YHT 405 bp overlap
ChIP endothelial cell of umbilical vein ENCFF091YHT 405 bp overlap
ChIP endothelial cell of umbilical vein ENCFF467WJF 82 bp overlap
ChIP endothelial cell of umbilical vein ENCFF467WJF 521 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 521 bp overlap
RB1 1 dataset
ChIP GM12878 ENCSR785OKZ.RB1.GM12878 293 bp overlap
RELB 1 dataset
ChIP L1236 GSE63736.RELB.L1236 90 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 950 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 812 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 728 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 416 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 779 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 462 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 756 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 798 bp overlap
SMAD3 3 datasets
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 136 bp overlap
ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 603 bp overlap
ChIP HMLE_Doxycicline_TGFb GSE104760.SMAD3.HMLE_Doxycicline_TGFb 243 bp overlap
SMARCA4 3 datasets
ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 197 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 654 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 224 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 609 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 691 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 990 bp overlap
SRF 1 dataset
ChIP K-562 ENCSR000BLK.SRF.K-562 114 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 365 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 325 bp overlap
TBR1 3 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 3 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 3 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 3 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX20 3 datasets
Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap
TBX21 3 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 3 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 3 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 11 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
ChIP G296S GSE85628.TBX5.G296S 553 bp overlap
ChIP G296S_2 GSE85628.TBX5.G296S_2 553 bp overlap
ChIP G296S_4 GSE85628.TBX5.G296S_4 152 bp overlap
ChIP G296S_4 GSE85628.TBX5.G296S_4 548 bp overlap
ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 615 bp overlap
ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 177 bp overlap
ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 426 bp overlap
ChIP hiPSC GSE81585.TBX5.hiPSC 328 bp overlap
TP63 22 datasets
ChIP BxPC-3 GSE115461.TP63.BxPC-3 458 bp overlap
Motif DE_48h DE_48h-TP63_MA0525.2 18 bp overlap
Motif DE_72h DE_72h-TP63_MA0525.2 18 bp overlap
ChIP EP156T GSE43111.TP63.EP156T 139 bp overlap
ChIP HaCaT_LacZ GSE60814.TP63.HaCaT_LacZ 144 bp overlap
ChIP HaCaT_LacZ_TGFB GSE60814.TP63.HaCaT_LacZ_TGFB 394 bp overlap
ChIP HaCaT_caRAS_TGFB GSE60814.TP63.HaCaT_caRAS_TGFB 378 bp overlap
ChIP HaCaT_dnRAS_TGFB GSE60814.TP63.HaCaT_dnRAS_TGFB 352 bp overlap
ChIP JHU-029 GSE88859.TP63.JHU-029 319 bp overlap
ChIP MCF-10A_Nutlin3A GSE111009.TP63.MCF-10A_Nutlin3A 561 bp overlap
ChIP SUIT-2 GSE115461.TP63.SUIT-2 346 bp overlap
ChIP TT GSE46837.TP63.TT 149 bp overlap
ChIP keratinocyte GSE56674.TP63.keratinocyte 440 bp overlap
ChIP keratinocyte_ADRIA GSE56674.TP63.keratinocyte_ADRIA 149 bp overlap
ChIP keratinocyte_CISP GSE56674.TP63.keratinocyte_CISP 285 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 384 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 374 bp overlap
ChIP keratinocyte_D4 GSE59824.TP63.keratinocyte_D4 357 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 354 bp overlap
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 210 bp overlap
ChIP keratinocyte_epidermal GSE67382.TP63.keratinocyte_epidermal 317 bp overlap
ChIP keratinocyte_epidermal_KDPAF GSE67382.TP63.keratinocyte_epidermal_KDPAF 265 bp overlap
TP73 2 datasets
Motif DE_48h DE_48h-TP73_MA0861.2 16 bp overlap
Motif DE_72h DE_72h-TP73_MA0861.2 16 bp overlap
Tbx6 3 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
ZEB1 1 dataset
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
ZFP28 1 dataset
ChIP HEK293 GSE76494.ZFP28.HEK293 140 bp overlap
ZNF143 1 dataset
ChIP GM12878 ENCSR936XTK.ZNF143.GM12878 213 bp overlap
ZNF18 1 dataset
ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 415 bp overlap
Zfp335 2 datasets
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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