chr21 : 36,099,712 – 36,100,295
583 bp 79 TFs 9 linked genes
This 583 bp open chromatin element is linked to 9 target genes and is bound by 79 transcription factors.
Linked Genes
9 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000233393 4.6 kb Proximal Proximity
ENSG00000289001 30.0 kb Distal Multiome+HiCAR
CBR1 30.0 kb Distal Multiome+HiCAR
CBR3 35.0 kb Distal Multiome
SETD4 39.5 kb Distal Multiome+HiCAR
CBR3-AS1 56.3 kb Distal Multiome
DOP1B 56.7 kb Distal Multiome
MORC3 220.2 kb Distal Multiome
CHAF1B 285.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:36,094,712 – 36,105,295
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
79 transcription factors
Source
Cell type
Arid3a 1 dataset
Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap
BCL11A 1 dataset
Motif DE_24h DE_24h-BCL11A_MA2324.1 7 bp overlap
CDX1 1 dataset
Motif DE_24h DE_24h-CDX1_MA0878.3 10 bp overlap
CDX2 1 dataset
Motif DE_24h DE_24h-CDX2_MA0465.3 8 bp overlap
E2F3 1 dataset
Motif DE_24h DE_24h-E2F3_MA0469.4 14 bp overlap
E2F6 2 datasets
Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap
ChIP H1 ENCFF785DWK 218 bp overlap
E2F7 1 dataset
Motif DE_24h DE_24h-E2F7_MA0758.1 14 bp overlap
E2F8 1 dataset
Motif DE_24h DE_24h-E2F8_MA0865.3 9 bp overlap
ETS2 1 dataset
Motif DE_24h DE_24h-ETS2_MA1484.2 9 bp overlap
ETV2 1 dataset
Motif DE_24h DE_24h-ETV2_MA0762.2 9 bp overlap
ETV5::FOXI1 1 dataset
Motif DE_24h DE_24h-ETV5FOXI1_MA1946.2 12 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap
FLI1 1 dataset
Motif DE_24h DE_24h-FLI1_MA0475.3 9 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 194 bp overlap
ChIP DE DE-FOXA2-2 371 bp overlap
FOXO1::ELF1 1 dataset
Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 1 dataset
Motif DE_24h DE_24h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 1 dataset
Motif DE_24h DE_24h-FOXO1FLI1_MA1956.2 13 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 570 bp overlap
ChIP DE DE-GATA4-2 583 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
GATA5 1 dataset
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 427 bp overlap
ChIP DE DE-GATA6-2 583 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 518 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 557 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 441 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 417 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 263 bp overlap
Gata3 1 dataset
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
HOXB4 1 dataset
Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap
HOXD4 1 dataset
Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap
HSF1 1 dataset
Motif DE_24h DE_24h-HSF1_MA0486.2 13 bp overlap
HSF4 1 dataset
Motif DE_24h DE_24h-HSF4_MA0771.1 13 bp overlap
Hmga1 1 dataset
Motif DE_24h DE_24h-Hmga1_MA2124.1 8 bp overlap
Hnf1A 2 datasets
Motif DE_24h DE_24h-Hnf1A_MA1991.2 10 bp overlap
Motif ES_0h ES_0h-Hnf1A_MA1991.2 10 bp overlap
IKZF1 1 dataset
Motif DE_24h DE_24h-IKZF1_MA1508.2 8 bp overlap
IKZF2 1 dataset
Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap
IRF3 1 dataset
Motif DE_24h DE_24h-IRF3_MA1418.2 17 bp overlap
IRF7 1 dataset
Motif DE_24h DE_24h-IRF7_MA0772.2 13 bp overlap
IRF9 1 dataset
Motif DE_24h DE_24h-IRF9_MA0653.1 15 bp overlap
JUN 4 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 443 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 431 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 279 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 287 bp overlap
MEIS1 2 datasets
Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap
Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap
NANOG 1 dataset
ChIP GM23338 ENCFF065NZG 311 bp overlap
NFATC3 1 dataset
Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap
Nfatc1 1 dataset
Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
PBX3 1 dataset
Motif DE_24h DE_24h-PBX3_MA1114.2 11 bp overlap
PHOX2A 2 datasets
Motif DE_24h DE_24h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_24h DE_24h-PHOX2A_MA0713.1 11 bp overlap
PKNOX1 1 dataset
Motif DE_24h DE_24h-PKNOX1_MA0782.3 10 bp overlap
POU1F1 1 dataset
Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 2 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 511 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 501 bp overlap
POU6F2 1 dataset
Motif DE_24h DE_24h-POU6F2_MA0793.2 9 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap
REL 1 dataset
Motif DE_24h DE_24h-REL_MA0101.1 10 bp overlap
RELA 1 dataset
Motif DE_24h DE_24h-RELA_MA0107.1 10 bp overlap
Rarb 1 dataset
Motif DE_24h DE_24h-Rarb_MA0858.1 17 bp overlap
SATB1 1 dataset
Motif DE_24h DE_24h-SATB1_MA1963.2 7 bp overlap
SMAD2 1 dataset
Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 415 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 410 bp overlap
SMAD2_3 6 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 583 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 583 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 583 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 553 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 583 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 374 bp overlap
SOX13 1 dataset
Motif DE_24h DE_24h-SOX13_MA1120.2 7 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 403 bp overlap
SOX2 1 dataset
Motif DE_24h DE_24h-SOX2_MA0143.5 7 bp overlap
SOX21 2 datasets
Motif DE_24h DE_24h-SOX21_MA0866.1 15 bp overlap
Motif DE_24h DE_24h-SOX21_MA0866.1 15 bp overlap
SREBF1 1 dataset
Motif DE_24h DE_24h-SREBF1_MA0829.3 10 bp overlap
Six3 1 dataset
Motif DE_24h DE_24h-Six3_MA0631.2 11 bp overlap
Sox1 1 dataset
Motif DE_24h DE_24h-Sox1_MA0870.1 15 bp overlap
Sox17 1 dataset
Motif DE_24h DE_24h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_24h DE_24h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_24h DE_24h-Sox5_MA0087.3 8 bp overlap
Sox7 1 dataset
Motif DE_24h DE_24h-Sox7_MA2095.1 10 bp overlap
Spi1 1 dataset
Motif DE_24h DE_24h-Spi1_MA0080.7 13 bp overlap
TAF1 1 dataset
ChIP H1 ENCFF478SZO 92 bp overlap
TFCP2 1 dataset
Motif DE_24h DE_24h-TFCP2_MA1968.2 9 bp overlap
TFDP1 1 dataset
Motif DE_24h DE_24h-TFDP1_MA1122.2 8 bp overlap
TGIF1 1 dataset
Motif DE_24h DE_24h-TGIF1_MA0796.1 12 bp overlap
TGIF2 1 dataset
Motif DE_24h DE_24h-TGIF2_MA0797.1 12 bp overlap
TGIF2LX 1 dataset
Motif DE_24h DE_24h-TGIF2LX_MA1571.1 12 bp overlap
TGIF2LY 1 dataset
Motif DE_24h DE_24h-TGIF2LY_MA1572.1 12 bp overlap
TRPS1 1 dataset
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
ZNF257 2 datasets
Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap
Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap
ZNF281 2 datasets
Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap
Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap
ZNF384 1 dataset
Motif DE_24h DE_24h-ZNF384_MA1125.2 8 bp overlap
ZNF547 1 dataset
Motif DE_24h DE_24h-ZNF547_MA2334.1 13 bp overlap
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