chr19 : 52,584,755 – 52,585,010

255 bp 55 TFs 3 linked genes

This 255 bp open chromatin element is linked to ENSG00000268886, ENSG00000290721, and ZNF137P and is bound by 55 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
ENSG00000268886	550 bp	At TSS	Proximity
ENSG00000290721	3.5 kb	Proximal	Proximity
ZNF137P	7.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 104 bp overlap

ChIP HepG2 ENCFF773YDL 104 bp overlap

BRD2 1 dataset

ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 209 bp overlap

BRD4 2 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 189 bp overlap

ChIP IMR-90_SENES GSE74238.BRD4.IMR-90_SENES 194 bp overlap

CTCF 1 dataset

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 154 bp overlap

ESR1 3 datasets

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 231 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 164 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 156 bp overlap

GLIS1 1 dataset

Motif ES_0h ES_0h-GLIS1_MA0735.2 15 bp overlap

GLIS3 1 dataset

Motif ES_0h ES_0h-GLIS3_MA0737.1 14 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 196 bp overlap

Hand1 1 dataset

Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap

Hand1::Tcf3 1 dataset

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

KLF1 1 dataset

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif ES_0h ES_0h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

KLF2 1 dataset

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

KLF3 1 dataset

Motif ES_0h ES_0h-KLF3_MA1516.2 10 bp overlap

KLF4 1 dataset

Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

KLF6 1 dataset

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

KLF7 1 dataset

Motif ES_0h ES_0h-KLF7_MA1959.2 8 bp overlap

KLF9 2 datasets

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 238 bp overlap

MED1 1 dataset

ChIP MCF-7_SHRARS_E2 GSE60270.MED1.MCF-7_SHRARS_E2 179 bp overlap

MPHOSPH8 1 dataset

ChIP H9 GSE95374.MPHOSPH8.H9 85 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 235 bp overlap

NFKB2 1 dataset

Motif ES_0h ES_0h-NFKB2_MA0778.2 11 bp overlap

OSR1 1 dataset

Motif ES_0h ES_0h-OSR1_MA1542.2 8 bp overlap

OSR2 1 dataset

Motif ES_0h ES_0h-OSR2_MA1646.2 8 bp overlap

PATZ1 1 dataset

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 255 bp overlap

ChIP K562 ENCFF648YPL 255 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 170 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 202 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 196 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 133 bp overlap

RBFOX2 2 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 193 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 193 bp overlap

REST 1 dataset

ChIP PANC-1 ENCSR000BJO.REST.PANC-1 120 bp overlap

SIRT6 1 dataset

ChIP K-562 ENCSR000AUB.SIRT6.K-562 80 bp overlap

SMAD2 1 dataset

Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 226 bp overlap

SP1 1 dataset

Motif ES_0h ES_0h-SP1_MA0079.5 9 bp overlap

SP2 1 dataset

Motif ES_0h ES_0h-SP2_MA0516.3 9 bp overlap

SP3 1 dataset

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

SP8 1 dataset

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

SP9 1 dataset

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

TP63 1 dataset

ChIP breast-organoid GSE113909.TP63.breast-organoid 116 bp overlap

ZBTB24 1 dataset

Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 255 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 234 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 140 bp overlap

ZBTB7B 1 dataset

Motif ES_0h ES_0h-ZBTB7B_MA0694.2 10 bp overlap

ZNF148 1 dataset

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF213 1 dataset

Motif ES_0h ES_0h-ZNF213_MA2121.1 12 bp overlap

ZNF320 1 dataset

Motif ES_0h ES_0h-ZNF320_MA1976.2 20 bp overlap

Zfx 1 dataset

Motif ES_0h ES_0h-Zfx_MA0146.3 10 bp overlap