chr18 : 62,720,845 – 62,721,018

173 bp 52 TFs 1 linked gene

This 173 bp open chromatin element is linked to PHLPP1 and is bound by 52 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PHLPP1		5.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

AR 1 dataset

ChIP LNCaP_R1881 GSE69043.AR.LNCaP_R1881 94 bp overlap

ARID2 1 dataset

ChIP Hep-G2 GSE69566.ARID2.Hep-G2 173 bp overlap

ASH2L 1 dataset

ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 131 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BRD4 1 dataset

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 92 bp overlap

CDK9 1 dataset

ChIP MV4-11_DMSO GSE82116.CDK9.MV4-11_DMSO 158 bp overlap

CHD1 1 dataset

ChIP WA01 ENCSR000AQK.CHD1.WA01 145 bp overlap

EZH2_phosphoT487 1 dataset

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 107 bp overlap

FEZF1 1 dataset

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 85 bp overlap

FOXA1 5 datasets

ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 64 bp overlap

ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 81 bp overlap

ChIP ZR751 GSE72249.FOXA1.ZR751 139 bp overlap

ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 140 bp overlap

ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 139 bp overlap

FOXK1 1 dataset

ChIP Hep-G2 ENCSR603BJQ.FOXK1.Hep-G2 119 bp overlap

GATA2 2 datasets

ChIP LNCaP GSE38391.GATA2.LNCaP 155 bp overlap

ChIP LNCaP GSE52725.GATA2.LNCaP 155 bp overlap

GATA3 4 datasets

ChIP MCF-7 GSE122847.GATA3.MCF-7 118 bp overlap

ChIP MCF-7 GSE51274.GATA3.MCF-7 93 bp overlap

ChIP MCF-7 GSE133072.GATA3.MCF-7 101 bp overlap

ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 116 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HSF1 1 dataset

ChIP MO91_27A_20UM GSE45852.HSF1.MO91_27A_20UM 134 bp overlap

KLF10 1 dataset

ChIP HEK293 ENCSR006GAQ.KLF10.HEK293 101 bp overlap

KLF4 1 dataset

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 156 bp overlap

KMT2A 10 datasets

ChIP HEK293T_C-term_C104 GSE90762.KMT2A.HEK293T_C-term_C104 52 bp overlap

ChIP HEK293T_C-term_C49 GSE90762.KMT2A.HEK293T_C-term_C49 158 bp overlap

ChIP HEK293T_N-term GSE90762.KMT2A.HEK293T_N-term 173 bp overlap

ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 173 bp overlap

ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 173 bp overlap

ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 94 bp overlap

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 173 bp overlap

ChIP RS4-11_DMSO-D3-180402 GSE127507.KMT2A.RS4-11_DMSO-D3-180402 173 bp overlap

ChIP SEM GSE83671.KMT2A.SEM 173 bp overlap

ChIP THP-1 GSE83671.KMT2A.THP-1 173 bp overlap

MEN1 2 datasets

ChIP PC-3 GSE132827.MEN1.PC-3 123 bp overlap

ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 148 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 150 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 173 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFATC2 1 dataset

ChIP CD4_CD28-ab GSE116695.NFATC2.CD4_CD28-ab 173 bp overlap

NUP98-HOXA9 1 dataset

ChIP HEK293-FT GSE62586.NUP98-HOXA9.HEK293-FT 65 bp overlap

OSR2 2 datasets

ChIP HEK293 ENCFF875BDB 166 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 107 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 173 bp overlap

PKNOX1 1 dataset

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 173 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 173 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCFF283AJL 154 bp overlap

PRPF4 2 datasets

ChIP Hep-G2 GSE120104.PRPF4.Hep-G2 156 bp overlap

ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 155 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm5 1 dataset

Motif DE_12h DE_12h-Prdm5_MA1999.2 11 bp overlap

RAD21 3 datasets

ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-000m-Flavo-000m 173 bp overlap

ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-020m-Flavo-000m 97 bp overlap

ChIP THP-1_Pam3csk-045m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-045m-Flavo-000m 110 bp overlap

RBFOX2 1 dataset

ChIP HepG2 ENCFF554DMZ 173 bp overlap

RNF2 1 dataset

ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 173 bp overlap

SIN3A 1 dataset

ChIP PFSK1 ENCSR000BOY.SIN3A.PFSK1 146 bp overlap

SMARCA4 5 datasets

ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 173 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 94 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 173 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 173 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 173 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 124 bp overlap

SMARCC1 3 datasets

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 153 bp overlap

ChIP DE_D1 S10-DE-d1-BAF155-exp1 173 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 173 bp overlap

SP7 1 dataset

ChIP HEK293 ENCSR468IJT.SP7.HEK293 69 bp overlap

SS18 1 dataset

ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 86 bp overlap

TLE3 1 dataset

ChIP LNCaP GSE94682.TLE3.LNCaP 61 bp overlap

WT1 1 dataset

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 83 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 145 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 92 bp overlap

ZNF213 1 dataset

ChIP HEK293 ENCSR295GRB.ZNF213.HEK293 72 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 173 bp overlap

ZNF382 1 dataset

Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap

ZNF558 1 dataset

Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap

ZNF580 1 dataset

ChIP HEK293 ENCSR668HOP.ZNF580.HEK293 115 bp overlap

ZNF629 1 dataset

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 52 bp overlap

ZXDB 1 dataset

ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 72 bp overlap