chr18 : 45,970,019 – 45,970,502

483 bp 79 TFs 1 linked gene

This 483 bp open chromatin element is linked to EPG5 and is bound by 79 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
EPG5		2.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

79 transcription factors

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 448 bp overlap

ChIP BLaER1 ENCFF460KDD 378 bp overlap

EOMES 2 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 169 bp overlap

ERF::FOXO1 1 dataset

Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap

ESR1 1 dataset

ChIP Ishikawa GSE99905.ESR1.Ishikawa 155 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

Motif DE_48h DE_48h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 483 bp overlap

ChIP DE DE-FOXA2-2 483 bp overlap

Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_48h DE_48h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

FOXE1 1 dataset

Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_48h DE_48h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_48h DE_48h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_48h DE_48h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_48h DE_48h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_48h DE_48h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_48h DE_48h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_48h DE_48h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_48h DE_48h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap

Foxl2 1 dataset

Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_48h DE_48h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_48h DE_48h-Foxo3_MA0157.4 7 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 483 bp overlap

ChIP DE DE-GATA4-2 483 bp overlap

GATA6 2 datasets

ChIP DE DE-GATA6-1 483 bp overlap

ChIP DE DE-GATA6-2 483 bp overlap

IRF5 1 dataset

Motif DE_48h DE_48h-IRF5_MA1420.1 14 bp overlap

MGA 1 dataset

Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap

MSC 1 dataset

Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap

MYF6 1 dataset

Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap

OSR1 1 dataset

Motif DE_48h DE_48h-OSR1_MA1542.2 8 bp overlap

OSR2 1 dataset

Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap

PAX3 1 dataset

Motif DE_48h DE_48h-PAX3_MA1546.2 14 bp overlap

PKNOX2 1 dataset

Motif DE_48h DE_48h-PKNOX2_MA0783.1 12 bp overlap

Ptf1A 1 dataset

Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap

RFX1 2 datasets

ChIP K-562 ENCSR041AXL.RFX1.K-562 206 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 214 bp overlap

SCRT1 1 dataset

Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 266 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 483 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 414 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 326 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 197 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 267 bp overlap

SNAI2 1 dataset

Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 272 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 360 bp overlap

SP5 1 dataset

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

TAL1 1 dataset

ChIP CD34 GSE52924.TAL1.CD34 111 bp overlap

TBR1 1 dataset

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap

TGIF1 1 dataset

Motif DE_48h DE_48h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_48h DE_48h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_48h DE_48h-TGIF2LX_MA1571.1 12 bp overlap

Tbx6 1 dataset

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

ZEB1 1 dataset

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF449 1 dataset

Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap

ZNF460 1 dataset

Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap

ZNF664 2 datasets

ChIP HEK293 ENCFF343XSW 157 bp overlap

ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 114 bp overlap

Zfp809 1 dataset

Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap