chr18 : 28,184,868 – 28,185,825
957 bp 85 TFs 1 linked gene
This 957 bp open chromatin element is linked to CDH2 and is bound by 85 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CDH2 7.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:28,179,868 – 28,190,825
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
85 transcription factors
Source
Cell type
Atoh1 3 datasets
Motif DE_36h DE_36h-Atoh1_MA1467.3 7 bp overlap
Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap
Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap
BACH2 3 datasets
Motif DE_36h DE_36h-BACH2_MA1101.3 11 bp overlap
Motif DE_48h DE_48h-BACH2_MA1101.3 11 bp overlap
Motif DE_60h DE_60h-BACH2_MA1101.3 11 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 101 bp overlap
EBF1 2 datasets
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 229 bp overlap
ERF::FIGLA 1 dataset
Motif DE_36h DE_36h-ERFFIGLA_MA1934.2 13 bp overlap
ESR1 2 datasets
ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 172 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 110 bp overlap
ESR2 4 datasets
Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap
Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
ETV1 2 datasets
Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap
Motif DE_60h DE_60h-ETV1_MA0761.3 9 bp overlap
ETV2::FIGLA 1 dataset
Motif DE_36h DE_36h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV5::FIGLA 1 dataset
Motif DE_36h DE_36h-ETV5FIGLA_MA1945.2 14 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_36h DE_36h-ETV5FOXO1_MA1947.2 10 bp overlap
Ebf4 2 datasets
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
Erg 2 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_60h DE_60h-Erg_MA0474.4 10 bp overlap
FIGLA 2 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FLI1::DRGX 2 datasets
Motif DE_36h DE_36h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_60h DE_60h-FLI1DRGX_MA1949.2 14 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 423 bp overlap
ChIP DE DE-FOXA2-2 478 bp overlap
GABPA 3 datasets
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap
ChIP VCaP_ETOH GSE49091.GABPA.VCaP_ETOH 126 bp overlap
GATA1::TAL1 2 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 2 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 651 bp overlap
ChIP DE DE-GATA4-2 775 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 375 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 378 bp overlap
GATA6 13 datasets
ChIP AGS GSE51936.GATA6.AGS 111 bp overlap
ChIP DE DE-GATA6-1 568 bp overlap
ChIP DE DE-GATA6-2 584 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 588 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 511 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 563 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 519 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 592 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 639 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 516 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 305 bp overlap
GLIS2 2 datasets
Motif DE_36h DE_36h-GLIS2_MA0736.1 14 bp overlap
Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap
GLIS3 2 datasets
Motif DE_36h DE_36h-GLIS3_MA0737.1 14 bp overlap
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 6 datasets
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
IKZF1 2 datasets
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
ISL2 2 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 404 bp overlap
MEIS1 2 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MITF 1 dataset
ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 225 bp overlap
NEUROD1 3 datasets
Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 6 datasets
Motif DE_36h DE_36h-NEUROG2_MA0669.1 10 bp overlap
Motif DE_36h DE_36h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_48h DE_48h-NEUROG2_MA0669.1 10 bp overlap
Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA0669.1 10 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
NFE2 3 datasets
Motif DE_36h DE_36h-NFE2_MA0841.2 10 bp overlap
Motif DE_48h DE_48h-NFE2_MA0841.2 10 bp overlap
Motif DE_60h DE_60h-NFE2_MA0841.2 10 bp overlap
NOTCH3 1 dataset
ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 178 bp overlap
NR2C1 2 datasets
Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
NR2F1 2 datasets
Motif DE_36h DE_36h-NR2F1_MA0017.3 12 bp overlap
Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap
NR2F2 2 datasets
Motif DE_36h DE_36h-NR2F2_MA1111.2 7 bp overlap
Motif DE_60h DE_60h-NR2F2_MA1111.2 7 bp overlap
NR4A2 2 datasets
Motif DE_36h DE_36h-NR4A2_MA0160.3 8 bp overlap
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Neurod2 3 datasets
Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Nr1H2 2 datasets
Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 506 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 490 bp overlap
PRDM9 1 dataset
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Ppara 2 datasets
Motif DE_36h DE_36h-Ppara_MA2338.1 7 bp overlap
Motif DE_60h DE_60h-Ppara_MA2338.1 7 bp overlap
RARB 2 datasets
Motif DE_36h DE_36h-RARB_MA1552.2 13 bp overlap
Motif DE_60h DE_60h-RARB_MA1552.2 13 bp overlap
RARG 2 datasets
Motif DE_36h DE_36h-RARG_MA1553.2 13 bp overlap
Motif DE_60h DE_60h-RARG_MA1553.2 13 bp overlap
RBPJ 3 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
RXRB 2 datasets
Motif DE_36h DE_36h-RXRB_MA1555.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA1555.1 14 bp overlap
RXRG 2 datasets
Motif DE_36h DE_36h-RXRG_MA1556.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA1556.1 14 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 136 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 521 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 463 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 436 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 310 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 412 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 506 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 531 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 240 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 236 bp overlap
SMARCC1 1 dataset
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 461 bp overlap
SNAI2 2 datasets
ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 224 bp overlap
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 317 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 383 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 493 bp overlap
SP4 1 dataset
Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPIB 1 dataset
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Stat6 1 dataset
Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 197 bp overlap
TFAP4::ETV1 1 dataset
Motif DE_36h DE_36h-TFAP4ETV1_MA1966.2 13 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
TWIST1 3 datasets
Motif DE_36h DE_36h-TWIST1_MA1123.3 8 bp overlap
Motif DE_48h DE_48h-TWIST1_MA1123.3 8 bp overlap
Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap
VEZF1 2 datasets
Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Wt1 1 dataset
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
ZBTB6 2 datasets
Motif DE_36h DE_36h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
ZEB1 2 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZIC1 2 datasets
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
ZIC4 2 datasets
Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
ZNF175 2 datasets
Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap
Motif DE_60h DE_60h-ZNF175_MA2332.1 9 bp overlap
ZNF263 1 dataset
Motif DE_36h DE_36h-ZNF263_MA0528.3 7 bp overlap
ZNF423 1 dataset
ChIP WTC11 ENCFF574PBR 317 bp overlap
ZNF519 1 dataset
ChIP HEK293T GSE78099.ZNF519.HEK293T 107 bp overlap
ZNF682 2 datasets
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap
ZNF707 1 dataset
Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap
ZNF76 3 datasets
Motif DE_36h DE_36h-ZNF76_MA1716.2 17 bp overlap
Motif DE_48h DE_48h-ZNF76_MA1716.2 17 bp overlap
Motif DE_60h DE_60h-ZNF76_MA1716.2 17 bp overlap
ZSCAN16 2 datasets
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
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