chr14 : 66,444,128 – 66,445,034
906 bp 99 TFs 2 linked genes
This 906 bp open chromatin element is linked to ENSG00000258561 and GPHN and is bound by 99 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000258561 63.3 kb Distal Multiome
GPHN 63.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:66,439,128 – 66,450,034
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
99 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP NGP GSE134626.ARID1A.NGP 361 bp overlap
ASCL1 4 datasets
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap
Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap
BARX1 1 dataset
Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap
BCL6 1 dataset
ChIP OCI-Ly1_UV GSE103125.BCL6.OCI-Ly1_UV 419 bp overlap
BSX 1 dataset
Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap
CEBPA 1 dataset
ChIP SGBS GSE41629.CEBPA.SGBS 71 bp overlap
CEBPB 1 dataset
ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 174 bp overlap
DLX1 1 dataset
Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap
DUX4 1 dataset
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Dlx2 1 dataset
Motif DE_60h DE_60h-Dlx2_MA0885.3 8 bp overlap
Dlx3 1 dataset
Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap
Dlx5 1 dataset
Motif DE_60h DE_60h-Dlx5_MA1476.3 8 bp overlap
EOMES 5 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 222 bp overlap
ESR1 3 datasets
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 155 bp overlap
ChIP breast-cancer_3487 GSE126004.ESR1.breast-cancer_3487 267 bp overlap
ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 203 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 258 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 137 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 212 bp overlap
FIGLA 4 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA1 1 dataset
ChIP breast-cancer_3487 GSE126004.FOXA1.breast-cancer_3487 194 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 498 bp overlap
ChIP DE DE-FOXA2-2 459 bp overlap
GATA2 2 datasets
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 211 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 186 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 813 bp overlap
ChIP DE DE-GATA4-2 846 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 442 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 653 bp overlap
ChIP DE DE-GATA6-2 883 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 346 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 565 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 315 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 905 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 603 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 689 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 564 bp overlap
GBX2 1 dataset
Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap
Gfi1B 1 dataset
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
HESX1 1 dataset
Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap
HOXA5 1 dataset
Motif DE_60h DE_60h-HOXA5_MA0158.2 8 bp overlap
HOXA6 1 dataset
Motif DE_60h DE_60h-HOXA6_MA1497.2 7 bp overlap
HOXA7 1 dataset
Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap
HOXB6 1 dataset
Motif DE_60h DE_60h-HOXB6_MA1500.2 7 bp overlap
HOXB7 1 dataset
Motif DE_60h DE_60h-HOXB7_MA1501.2 7 bp overlap
HOXB8 1 dataset
Motif DE_60h DE_60h-HOXB8_MA1502.2 7 bp overlap
HOXD8 1 dataset
Motif DE_60h DE_60h-HOXD8_MA0910.3 7 bp overlap
Hmx2 1 dataset
Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap
Hmx3 1 dataset
Motif DE_60h DE_60h-Hmx3_MA0898.2 9 bp overlap
KDM1A 1 dataset
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 407 bp overlap
LBX2 1 dataset
Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap
LHX2 1 dataset
Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap
MAX 1 dataset
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 166 bp overlap
MEIS1 1 dataset
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MGA 4 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MSX1 1 dataset
Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap
Msx3 1 dataset
Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap
NEUROD1 1 dataset
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 155 bp overlap
NKX3-1 1 dataset
ChIP islet ERP004003.NKX3-1.islet 232 bp overlap
NR1D1 1 dataset
Motif DE_60h DE_60h-NR1D1_MA1531.2 14 bp overlap
NR1D2 1 dataset
Motif DE_60h DE_60h-NR1D2_MA1532.2 15 bp overlap
Nobox 1 dataset
Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap
Nr2F6 1 dataset
Motif DE_60h DE_60h-Nr2F6_MA0728.1 15 bp overlap
ONECUT3 1 dataset
Motif DE_60h DE_60h-ONECUT3_MA0757.2 12 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 246 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH3 GSE83726.PAX3-FOXO1.RH3 195 bp overlap
PHOX2A 1 dataset
Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 658 bp overlap
POLR2A 7 datasets
ChIP breast epithelium ENCFF960NNA 431 bp overlap
ChIP gastroesophageal sphincter ENCFF070PCA 184 bp overlap
ChIP sigmoid colon ENCFF725QFT 417 bp overlap
ChIP sigmoid colon ENCFF748YVT 187 bp overlap
ChIP stomach ENCFF820WZN 137 bp overlap
ChIP transverse colon ENCFF607LKE 371 bp overlap
ChIP transverse colon ENCFF610RWV 425 bp overlap
Pax7 1 dataset
Motif DE_60h DE_60h-Pax7_MA0680.3 10 bp overlap
Ptf1A 4 datasets
Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap
RARA 1 dataset
Motif DE_60h DE_60h-RARA_MA0729.1 18 bp overlap
RAX 1 dataset
Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap
REST 1 dataset
ChIP GM12878 ENCSR000BGF.REST.GM12878 60 bp overlap
SATB1 1 dataset
Motif DE_60h DE_60h-SATB1_MA1963.2 7 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 216 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 828 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 637 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 444 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 792 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 588 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 265 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 305 bp overlap
SMARCA4 1 dataset
ChIP TTC-1240_R377H GSE124903.SMARCA4.TTC-1240_R377H 340 bp overlap
SNAI1 4 datasets
Motif DE_36h DE_36h-SNAI1_MA1558.2 7 bp overlap
Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap
Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap
Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap
SNAI3 4 datasets
Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap
Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap
SOX15 1 dataset
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 286 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 388 bp overlap
SP5 1 dataset
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Stat2 1 dataset
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Stat6 1 dataset
Motif DE_60h DE_60h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 236 bp overlap
TBR1 4 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 4 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 4 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 4 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 4 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX21 4 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 4 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 4 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 4 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TCF12 4 datasets
Motif DE_36h DE_36h-TCF12_MA1648.2 7 bp overlap
Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap
Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap
Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 255 bp overlap
TCF3 4 datasets
Motif DE_36h DE_36h-TCF3_MA0522.4 7 bp overlap
Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap
Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap
Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap
TCF4 4 datasets
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap
Tbx6 4 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
Tfcp2l1 3 datasets
Motif DE_48h DE_48h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_60h DE_60h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_72h DE_72h-Tfcp2l1_MA0145.2 14 bp overlap
ZEB1 4 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF16 4 datasets
Motif DE_36h DE_36h-ZNF16_MA1654.2 21 bp overlap
Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap
Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap
Motif DE_72h DE_72h-ZNF16_MA1654.2 21 bp overlap
ZNF382 1 dataset
Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap
Zic1::Zic2 3 datasets
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 3 datasets
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 3 datasets
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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