chr14:20,644,459–20,645,301

chr14 : 20,644,459 – 20,645,301

842 bp 52 TFs 9 linked genes

This 842 bp open chromatin element is linked to 9 target genes and is bound by 52 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RNASE4		39.8 kb	Distal	Multiome
ANG		39.8 kb	Distal	Multiome
EGILA		62.3 kb	Distal	Multiome
RNASE1		158.1 kb	Distal	Multiome
PNP		175.4 kb	Distal	Multiome
PIP4P1		183.4 kb	Distal	Multiome
APEX1		189.5 kb	Distal	Multiome
OSGEP		189.7 kb	Distal	Multiome
TEP1		231.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

BACH1 1 dataset

Motif DE_60h DE_60h-BACH1_MA1633.2 9 bp overlap

BACH2 1 dataset

Motif DE_60h DE_60h-BACH2_MA1101.3 11 bp overlap

CREB1 1 dataset

ChIP LNCaP GSE63034.CREB1.LNCaP 121 bp overlap

CTCFL 1 dataset

Motif DE_60h DE_60h-CTCFL_MA1102.3 8 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_60h DE_60h-ELK1HOXA1_MA1931.1 14 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 344 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 493 bp overlap

FOS::JUN 1 dataset

Motif DE_60h DE_60h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUND 1 dataset

Motif DE_60h DE_60h-FOSJUND_MA1141.2 9 bp overlap

FOSL1 1 dataset

Motif DE_60h DE_60h-FOSL1_MA0477.3 9 bp overlap

FOSL1::JUN 1 dataset

Motif DE_60h DE_60h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 1 dataset

Motif DE_60h DE_60h-FOSL1JUNB_MA1137.2 9 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 620 bp overlap

ChIP DE DE-FOXA2-2 630 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 801 bp overlap

ChIP DE DE-GATA4-2 647 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 842 bp overlap

ChIP DE DE-GATA6-2 701 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 842 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 609 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_60h DE_60h-HOXB2ELK1_MA1957.1 14 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 253 bp overlap

Motif DE_60h DE_60h-JDP2_MA0655.1 9 bp overlap

Motif DE_60h DE_60h-JUNB_MA0490.3 9 bp overlap

Motif DE_60h DE_60h-JUND_MA0491.3 9 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 542 bp overlap

KLF4 4 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 198 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 233 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 144 bp overlap

ChIP WIBR3 GSE130417.KLF4.WIBR3 127 bp overlap

MEIS1 1 dataset

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-NFE2_MA0841.2 10 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 135 bp overlap

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

PATZ1 1 dataset

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 383 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 671 bp overlap

PRDM14 1 dataset

ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 842 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 332 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 842 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 842 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 169 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 337 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 285 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 443 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

ChIP OCI-Ly3 GSE56857.SPIB.OCI-Ly3 205 bp overlap

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

ChIP hESC GSE122298.TBP.hESC 132 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 110 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 183 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 321 bp overlap

TFAP2C 2 datasets

ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 177 bp overlap

ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 175 bp overlap

ZNF157 1 dataset

Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap

ZNF549 1 dataset

Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap