chr12 : 5,276,469 – 5,277,121

652 bp 66 TFs 1 linked gene

This 652 bp open chromatin element is linked to ENSG00000256417 and is bound by 66 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000256417		13.8 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

66 transcription factors

ASXL3 2 datasets

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 305 bp overlap

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 301 bp overlap

BAP1 1 dataset

ChIP NCI-H1963_shASXL3 GSE145028.BAP1.NCI-H1963_shASXL3 330 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

BRD4 6 datasets

ChIP HCC1395 GSE63581.BRD4.HCC1395 232 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 300 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 260 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 350 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 614 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 194 bp overlap

CTCF 2 datasets

ChIP endodermal cell ENCFF471YCZ 252 bp overlap

ChIP glioblastoma_GBM3565 GSE139416.CTCF.glioblastoma_GBM3565 303 bp overlap

EOMES 2 datasets

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 338 bp overlap

ESR1 1 dataset

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 521 bp overlap

EZH2 3 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 330 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 141 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 293 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 648 bp overlap

ChIP DE DE-FOXA2-2 633 bp overlap

FOXF2 1 dataset

Motif DE_72h DE_72h-FOXF2_MA0030.2 9 bp overlap

Foxj3 1 dataset

Motif DE_72h DE_72h-Foxj3_MA0851.2 9 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 547 bp overlap

ChIP DE DE-GATA4-2 594 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 652 bp overlap

ChIP DE DE-GATA6-2 528 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 513 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 289 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 456 bp overlap

ChIP foregut GSE117136.GATA6.foregut 285 bp overlap

Hic1 1 dataset

Motif DE_72h DE_72h-Hic1_MA0739.2 8 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 225 bp overlap

KLF3 1 dataset

Motif DE_72h DE_72h-KLF3_MA1516.2 10 bp overlap

Lhx3 1 dataset

Motif DE_72h DE_72h-Lhx3_MA0135.2 12 bp overlap

MED1 1 dataset

ChIP MCF-7_SHRARS_E2 GSE60270.MED1.MCF-7_SHRARS_E2 191 bp overlap

MGA 1 dataset

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH3 GSE83726.PAX3-FOXO1.RH3 273 bp overlap

PKNOX2 1 dataset

Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap

POU4F1 1 dataset

Motif DE_72h DE_72h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_72h DE_72h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_72h DE_72h-POU4F3_MA0791.2 12 bp overlap

POU5F1 1 dataset

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 157 bp overlap

PROP1 1 dataset

Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap

RREB1 1 dataset

Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap

SIX2 3 datasets

ChIP HEK GSE73865.SIX2.HEK 205 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 149 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 164 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 167 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 652 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 535 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 279 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 179 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 452 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 652 bp overlap

SOX18 1 dataset

Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap

SOX4 1 dataset

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

SRY 1 dataset

Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Sox6 1 dataset

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

TAL1 1 dataset

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 91 bp overlap

TBR1 1 dataset

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

TGIF1 1 dataset

Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap

TP63 5 datasets

ChIP JHU-029 GSE88859.TP63.JHU-029 147 bp overlap

ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 169 bp overlap

ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 181 bp overlap

ChIP keratinocyte_D4 GSE59824.TP63.keratinocyte_D4 174 bp overlap

ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 147 bp overlap

Tbx6 1 dataset

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ZNF140 1 dataset

Motif DE_72h DE_72h-ZNF140_MA1589.2 19 bp overlap

ZNF24 1 dataset

Motif DE_72h DE_72h-ZNF24_MA1124.1 13 bp overlap

ZNF682 1 dataset

Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap

ZNF708 1 dataset

Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap