chr11:68,879,344–68,879,843

chr11 : 68,879,344 – 68,879,843

499 bp 69 TFs 7 linked genes

This 499 bp open chromatin element is linked to 7 target genes and is bound by 69 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MRPL21		24.3 kb	Distal	Multiome
IGHMBP2		24.3 kb	Distal	Multiome
CPT1A		39.9 kb	Distal	Multiome
TESMIN		128.9 kb	Distal	Multiome
TPCN2		169.4 kb	Distal	Multiome
GAL		195.0 kb	Distal	Multiome
ENSG00000260808		262.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

69 transcription factors

ChIP WA01 ENCSR000BQU.ATF2.WA01 149 bp overlap

Motif DE_72h DE_72h-Alx1_MA0854.2 8 bp overlap

Motif DE_72h DE_72h-Alx4_MA0853.2 12 bp overlap

Motif DE_72h DE_72h-Arx_MA0874.2 10 bp overlap

BARX1 1 dataset

Motif DE_72h DE_72h-BARX1_MA0875.2 6 bp overlap

BMPR1A 1 dataset

ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 117 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD3.K-562_dilution-6-100 102 bp overlap

Motif DE_72h DE_72h-BSX_MA0876.2 6 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 204 bp overlap

ChIP K562 ENCFF673OEZ 391 bp overlap

ChIP parathyroid adenoma ENCFF173NJK 293 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 85 bp overlap

Motif DE_72h DE_72h-DLX1_MA0879.3 6 bp overlap

Motif DE_72h DE_72h-DLX6_MA0882.2 6 bp overlap

Motif DE_72h DE_72h-Dlx3_MA0880.2 6 bp overlap

Motif DE_72h DE_72h-Dlx4_MA0881.2 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 210 bp overlap

ESR1 3 datasets

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 154 bp overlap

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 141 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 212 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 290 bp overlap

ChIP DE DE-FOXA2-2 284 bp overlap

FOXD3 1 dataset

Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap

FOXO3 1 dataset

ChIP K-562 GSE97661.FOXO3.K-562 119 bp overlap

GATA1 3 datasets

ChIP K-562 GSE107726.GATA1.K-562 166 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 200 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 201 bp overlap

GATA2 1 dataset

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 398 bp overlap

ChIP DE DE-GATA4-2 482 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP G296S GSE85628.GATA4.G296S 213 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 213 bp overlap

ChIP foregut GSE117136.GATA4.foregut 315 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 344 bp overlap

GATA6 14 datasets

ChIP DE DE-GATA6-1 407 bp overlap

ChIP DE DE-GATA6-2 497 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 348 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 349 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 386 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 394 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 403 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 413 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 442 bp overlap

ChIP foregut GSE117136.GATA6.foregut 363 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 379 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 271 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 285 bp overlap

Motif DE_72h DE_72h-GBX2_MA0890.2 6 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap

HESX1 1 dataset

Motif DE_72h DE_72h-HESX1_MA0894.2 6 bp overlap

HOXA7 1 dataset

Motif DE_72h DE_72h-HOXA7_MA1498.3 6 bp overlap

Motif DE_72h DE_72h-Hmx1_MA0896.2 9 bp overlap

Motif DE_72h DE_72h-Hmx2_MA0897.2 15 bp overlap

Motif DE_72h DE_72h-Hmx3_MA0898.2 9 bp overlap

IKZF1 3 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 237 bp overlap

ChIP K562 ENCFF771OHZ 89 bp overlap

ChIP K562 ENCFF771OHZ 359 bp overlap

Motif DE_72h DE_72h-LBX2_MA0699.2 6 bp overlap

Motif DE_72h DE_72h-LHX2_MA0700.3 6 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 208 bp overlap

MEIS1 2 datasets

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MGA::EVX1 1 dataset

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

Motif DE_72h DE_72h-MSC_MA0665.1 10 bp overlap

Motif DE_72h DE_72h-MSX1_MA0666.3 6 bp overlap

Motif DE_72h DE_72h-MSX2_MA0708.3 6 bp overlap

ChIP K-562 ENCSR737LTZ.MYNN.K-562 122 bp overlap

Motif DE_72h DE_72h-Msx3_MA0709.2 6 bp overlap

NKX2-5 1 dataset

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 194 bp overlap

Nobox 1 dataset

Motif DE_72h DE_72h-Nobox_MA0125.2 6 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 255 bp overlap

Motif DE_72h DE_72h-RAX_MA0718.2 6 bp overlap

RELA 3 datasets

ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 107 bp overlap

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 193 bp overlap

ChIP aortic-endothelial-cell_IL1B_D40 GSE139377.RELA.aortic-endothelial-cell_IL1B_D40 158 bp overlap

Rhox11 1 dataset

Motif DE_72h DE_72h-Rhox11_MA0629.2 9 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 261 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 168 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 441 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 125 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 310 bp overlap

SMARCC1 2 datasets

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 317 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 325 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 289 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 499 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 227 bp overlap

ChIP K562 ENCFF059YCJ 353 bp overlap

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 156 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 194 bp overlap

SS18 3 datasets

ChIP SYO-1 GSE108025.SS18.SYO-1 473 bp overlap

ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 333 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 206 bp overlap

SUPT5H 1 dataset

ChIP HeLa_DOX GSE125534.SUPT5H.HeLa_DOX 114 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

TARDBP 2 datasets

ChIP K-562 GSE120104.TARDBP.K-562 152 bp overlap

ChIP K-562 ENCSR429XTR.TARDBP.K-562 152 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 152 bp overlap

TRIM24 1 dataset

ChIP LNCaP_DHT GSE69331.TRIM24.LNCaP_DHT 141 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 102 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCFF799ATK 58 bp overlap

ZNF512 1 dataset

ChIP K562 ENCFF601EMZ 152 bp overlap