chr10 : 48,284,741 – 48,285,439
698 bp 48 TFs 1 linked gene
This 698 bp open chromatin element is linked to MAPK8 and is bound by 48 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MAPK8 21.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:48,279,741 – 48,290,439
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
48 transcription factors
Source
Cell type
CLOCK 1 dataset
ChIP U2OS GSE44236.CLOCK.U2OS 177 bp overlap
DPF2 2 datasets
ChIP GM12878 ENCFF681AJV 423 bp overlap
ChIP GM12878 ENCSR509FWH.DPF2.GM12878 207 bp overlap
E2F6 3 datasets
ChIP K-562 ENCSR000BLI.E2F6.K-562 122 bp overlap
ChIP K562 ENCFF136LTS 325 bp overlap
ChIP K562 ENCFF136LTS 325 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 253 bp overlap
ESR1 1 dataset
ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 282 bp overlap
ETS1 1 dataset
ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 352 bp overlap
EZH2 1 dataset
ChIP Karpas-422_CPI360-D8 GSE134136.EZH2.Karpas-422_CPI360-D8 288 bp overlap
FLI1 1 dataset
ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 198 bp overlap
FOXA2 1 dataset
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 246 bp overlap
GATA1 5 datasets
ChIP K-562 GSE107726.GATA1.K-562 287 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 148 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 213 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 206 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
GATA2 13 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 139 bp overlap
ChIP K562 ENCFF513FTZ 301 bp overlap
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 273 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 227 bp overlap
GATA3 3 datasets
ChIP A1A3_Brg1KD_EtOH GSE112491.GATA3.A1A3_Brg1KD_EtOH 162 bp overlap
ChIP T-47D GSE51274.GATA3.T-47D 245 bp overlap
ChIP T47D-A1-2_EtOH GSE112491.GATA3.T47D-A1-2_EtOH 395 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 363 bp overlap
GATA4 15 datasets
ChIP DE DE-GATA4-1 518 bp overlap
ChIP DE DE-GATA4-2 562 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 482 bp overlap
GATA5 12 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 26 datasets
ChIP AGS GSE51705.GATA6.AGS 212 bp overlap
ChIP AGS GSE51936.GATA6.AGS 144 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 141 bp overlap
ChIP DE DE-GATA6-1 479 bp overlap
ChIP DE DE-GATA6-2 559 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 692 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 676 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 698 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 698 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 698 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 698 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 279 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 649 bp overlap
ChIP foregut GSE117136.GATA6.foregut 427 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 566 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 498 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 235 bp overlap
Gata3 9 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HCFC1R1 1 dataset
ChIP cartilage GSE100311.HCFC1R1.cartilage 292 bp overlap
HIF1A 1 dataset
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 226 bp overlap
IKZF1 1 dataset
ChIP GM12878 ENCFF616FJX 62 bp overlap
IRF3 3 datasets
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 382 bp overlap
L3MBTL2 2 datasets
ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 369 bp overlap
ChIP K562 ENCFF320EQC 488 bp overlap
MAX 1 dataset
ChIP K-562 ENCSR000EFV.MAX.K-562 106 bp overlap
MED1 1 dataset
ChIP GM12878 GSE93080.MED1.GM12878 174 bp overlap
MGA::EVX1 3 datasets
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
MLLT1 1 dataset
ChIP GM12878 ENCFF995GXC 247 bp overlap
MTA2 1 dataset
ChIP GM12878 ENCSR293QAR.MTA2.GM12878 146 bp overlap
NBN 1 dataset
ChIP GM12878 ENCSR278SQL.NBN.GM12878 352 bp overlap
PAX5 2 datasets
ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 197 bp overlap
ChIP GM12878 ENCSR000BHD.PAX5.GM12878 109 bp overlap
RBPJ 1 dataset
ChIP NHEK GSE29498.RBPJ.NHEK 155 bp overlap
RELB 1 dataset
ChIP GM12878 ENCSR387QUV.RELB.GM12878 330 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 205 bp overlap
Rarb 3 datasets
Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap
Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap
Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 545 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 430 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 451 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 443 bp overlap
SMARCA4 2 datasets
ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 406 bp overlap
ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 323 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 414 bp overlap
SP5 2 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPI1 2 datasets
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 204 bp overlap
ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 321 bp overlap
SUZ12 3 datasets
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 253 bp overlap
ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 289 bp overlap
ChIP Karpas-422_CPI360-D4 GSE134136.SUZ12.Karpas-422_CPI360-D4 163 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 300 bp overlap
THRA 3 datasets
Motif DE_36h DE_36h-THRA_MA1969.2 18 bp overlap
Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap
Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap
TRIM24 1 dataset
ChIP K-562 ENCSR907MZR.TRIM24.K-562 203 bp overlap
TRPS1 10 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ChIP T-47D GSE114213.TRPS1.T-47D 215 bp overlap
ZNF189 6 datasets
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap
Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap
ZNF592 2 datasets
ChIP GM12878 ENCSR173ZVL.ZNF592.GM12878 233 bp overlap
ChIP GM12878 ENCSR173ZVL.ZNF592.GM12878 122 bp overlap
ZNF687 1 dataset
ChIP GM12878 ENCSR859FDL.ZNF687.GM12878 87 bp overlap
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