chr7 : 117,689,231 – 117,690,096
865 bp 58 TFs 1 linked gene
This 865 bp open chromatin element is linked to CFTR and is bound by 58 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CFTR at TSS At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:117,684,231 – 117,695,096
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
58 transcription factors
Source
Cell type
AR 1 dataset
ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 203 bp overlap
BRD4 1 dataset
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 221 bp overlap
CDX2 2 datasets
ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 178 bp overlap
ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 333 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 214 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 477 bp overlap
ESR1 1 dataset
ChIP MCF-7 GSE68356.ESR1.MCF-7 226 bp overlap
ESR2 3 datasets
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap
ESRRB 1 dataset
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 3 datasets
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap
FOXA1 2 datasets
ChIP HEK293_r261g_TFS GSE123618.FOXA1.HEK293_r261g_TFS 204 bp overlap
ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 201 bp overlap
FOXA2 3 datasets
ChIP Caco-2 GSE66218.FOXA2.Caco-2 175 bp overlap
ChIP DE DE-FOXA2-1 652 bp overlap
ChIP DE DE-FOXA2-2 773 bp overlap
FOXC2 2 datasets
Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD2 2 datasets
Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap
Motif DE_72h DE_72h-FOXD2_MA0847.4 11 bp overlap
FOXD3 2 datasets
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXE1 2 datasets
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
FOXL2 1 dataset
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 131 bp overlap
Foxj3 2 datasets
Motif DE_60h DE_60h-Foxj3_MA0851.2 9 bp overlap
Motif DE_72h DE_72h-Foxj3_MA0851.2 9 bp overlap
GATA2 1 dataset
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 635 bp overlap
ChIP DE DE-GATA4-2 773 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 562 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 573 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 485 bp overlap
GATA6 16 datasets
ChIP AGS GSE51705.GATA6.AGS 198 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 229 bp overlap
ChIP DE DE-GATA6-1 710 bp overlap
ChIP DE DE-GATA6-2 698 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 439 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 479 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 578 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 543 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 426 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 186 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 503 bp overlap
ChIP foregut GSE117136.GATA6.foregut 491 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 511 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 373 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 299 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 3 datasets
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
HNF4A 4 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 182 bp overlap
ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 181 bp overlap
ChIP GP5D GSE51234.HNF4A.GP5D 352 bp overlap
ChIP KATO-III GSE114018.HNF4A.KATO-III 165 bp overlap
IKZF2 3 datasets
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
IRF3 2 datasets
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
IRF4 3 datasets
Motif DE_48h DE_48h-IRF4_MA1419.2 14 bp overlap
Motif DE_60h DE_60h-IRF4_MA1419.2 14 bp overlap
Motif DE_72h DE_72h-IRF4_MA1419.2 14 bp overlap
IRF5 3 datasets
Motif DE_48h DE_48h-IRF5_MA1420.1 14 bp overlap
Motif DE_60h DE_60h-IRF5_MA1420.1 14 bp overlap
Motif DE_72h DE_72h-IRF5_MA1420.1 14 bp overlap
IRF8 3 datasets
Motif DE_48h DE_48h-IRF8_MA0652.2 13 bp overlap
Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap
Motif DE_72h DE_72h-IRF8_MA0652.2 13 bp overlap
IRF9 3 datasets
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
ISL2 3 datasets
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap
JDP2 3 datasets
Motif DE_48h DE_48h-JDP2_MA0655.1 9 bp overlap
Motif DE_60h DE_60h-JDP2_MA0655.1 9 bp overlap
Motif DE_72h DE_72h-JDP2_MA0655.1 9 bp overlap
MYOD1 1 dataset
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 181 bp overlap
Msgn1 3 datasets
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap
Motif DE_72h DE_72h-Msgn1_MA1524.3 10 bp overlap
NCAPH2 1 dataset
ChIP RMG-I GSE120058.NCAPH2.RMG-I 676 bp overlap
NFE2 3 datasets
Motif DE_48h DE_48h-NFE2_MA0841.2 10 bp overlap
Motif DE_60h DE_60h-NFE2_MA0841.2 10 bp overlap
Motif DE_72h DE_72h-NFE2_MA0841.2 10 bp overlap
NR2C2 3 datasets
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA1538.1 15 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1538.1 15 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1538.1 15 bp overlap
NR2F6 3 datasets
Motif DE_48h DE_48h-NR2F6_MA1539.1 15 bp overlap
Motif DE_60h DE_60h-NR2F6_MA1539.1 15 bp overlap
Motif DE_72h DE_72h-NR2F6_MA1539.1 15 bp overlap
Nkx3-2 3 datasets
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap
Nr5A2 1 dataset
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
PAX5 1 dataset
ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 175 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 353 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 567 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 296 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 389 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 323 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 200 bp overlap
SOX10 4 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 595 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 530 bp overlap
SP5 1 dataset
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPIB 1 dataset
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
THAP1 3 datasets
Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap
Motif DE_60h DE_60h-THAP1_MA0597.3 8 bp overlap
Motif DE_72h DE_72h-THAP1_MA0597.3 8 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZNF189 1 dataset
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF257 3 datasets
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF263 1 dataset
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
ZNF317 1 dataset
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
ZNF768 3 datasets
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
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