chr6 : 28,171,036 – 28,171,660
624 bp 67 TFs 13 linked genes
This 624 bp open chromatin element is linked to 13 target genes and is bound by 67 transcription factors.
Linked Genes
13 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000280107 191 bp At TSS Proximity
ZKSCAN8P1 9.2 kb Proximal Proximity
ZKSCAN8 29.5 kb Distal Multiome
ZSCAN16-AS1 34.6 kb Distal Multiome
ZSCAN9 53.9 kb Distal Multiome
ZKSCAN4 80.8 kb Distal Multiome
ZSCAN26 95.9 kb Distal Multiome
PGBD1 110.1 kb Distal Multiome
ZKSCAN3 178.5 kb Distal Multiome
ZSCAN12 228.3 kb Distal Multiome
ZSCAN23 272.1 kb Distal Multiome
H2AC17 278.2 kb Distal Multiome
H3C12 278.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:28,166,036 – 28,176,660
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
67 transcription factors
Source
Cell type
ARNTL 1 dataset
ChIP U2OS_trough_DMSO GSE85096.ARNTL.U2OS_trough_DMSO 259 bp overlap
BCL11A 2 datasets
Motif DE_60h DE_60h-BCL11A_MA2324.1 7 bp overlap
Motif DE_72h DE_72h-BCL11A_MA2324.1 7 bp overlap
BRD4 1 dataset
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 162 bp overlap
DMRTA1 3 datasets
Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap
DMRTA2 3 datasets
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap
DPRX 2 datasets
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 394 bp overlap
ERF::FOXI1 2 datasets
Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap
ESR1 1 dataset
ChIP MCF-7_LTED GSE86538.ESR1.MCF-7_LTED 109 bp overlap
EZH2 1 dataset
ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 69 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 540 bp overlap
ChIP DE DE-FOXA2-2 480 bp overlap
FOXD3 2 datasets
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXO1::ELF1 2 datasets
Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 2 datasets
Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap
GATA1 1 dataset
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 141 bp overlap
GATA2 1 dataset
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 534 bp overlap
ChIP DE DE-GATA4-2 592 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 443 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 411 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 591 bp overlap
ChIP DE DE-GATA6-2 624 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 439 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 501 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 483 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 526 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 555 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 465 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 499 bp overlap
ChIP foregut GSE117136.GATA6.foregut 459 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 325 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 267 bp overlap
IKZF1 2 datasets
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 364 bp overlap
MEIS1 2 datasets
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MTF2 1 dataset
ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 303 bp overlap
MYF6 3 datasets
Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
Motif DE_72h DE_72h-MYF6_MA0667.1 10 bp overlap
MZF1 2 datasets
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
NFIA 2 datasets
Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap
Motif DE_72h DE_72h-NFIA_MA0670.2 6 bp overlap
NFIX 2 datasets
Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap
Motif DE_72h DE_72h-NFIX_MA0671.2 6 bp overlap
NOTCH3 1 dataset
ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 160 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 124 bp overlap
OSR1 2 datasets
Motif DE_60h DE_60h-OSR1_MA1542.2 8 bp overlap
Motif DE_72h DE_72h-OSR1_MA1542.2 8 bp overlap
PBX1 2 datasets
Motif DE_60h DE_60h-PBX1_MA0070.2 9 bp overlap
Motif DE_72h DE_72h-PBX1_MA0070.2 9 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA 3 datasets
Motif DE_48h DE_48h-RARA_MA0730.1 17 bp overlap
Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap
Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap
Rarb 3 datasets
Motif DE_48h DE_48h-Rarb_MA0858.1 17 bp overlap
Motif DE_60h DE_60h-Rarb_MA0858.1 17 bp overlap
Motif DE_72h DE_72h-Rarb_MA0858.1 17 bp overlap
SIX1 1 dataset
Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap
SIX2 1 dataset
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 167 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 488 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 459 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 275 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 375 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 406 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 453 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 195 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 188 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 394 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 297 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 559 bp overlap
SRY 2 datasets
Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
Six3 2 datasets
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Motif DE_72h DE_72h-Six3_MA0631.2 11 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 244 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 351 bp overlap
TBP 1 dataset
ChIP hESC_2h GSE122298.TBP.hESC_2h 299 bp overlap
TBX2 2 datasets
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX3 2 datasets
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TCF7L1 2 datasets
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
Yy1 2 datasets
Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap
Motif DE_72h DE_72h-Yy1_MA0095.4 8 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 134 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 165 bp overlap
ZNF189 3 datasets
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap
ZNF331 2 datasets
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap
ZNF410 2 datasets
Motif DE_60h DE_60h-ZNF410_MA0752.2 16 bp overlap
Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap
ZNF547 3 datasets
Motif DE_60h DE_60h-ZNF547_MA2334.1 13 bp overlap
Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap
ChIP HEK293 GSE76494.ZNF547.HEK293 207 bp overlap
ZNF586 1 dataset
ChIP HEK293 GSE76494.ZNF586.HEK293 207 bp overlap
ZNF675 4 datasets
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 146 bp overlap
ZNF766 1 dataset
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
ZSCAN16 2 datasets
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_72h DE_72h-ZSCAN16_MA2100.1 18 bp overlap
Zic1::Zic2 2 datasets
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 4 datasets
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 2 datasets
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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