Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZSCAN16-AS1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZSCAN16-AS1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZSCAN16-AS1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:27,836,792–27,839,128 | 298.4 kb | Distal (>10kb) Multiome | 1131 | |
| chr6:27,865,093–27,868,152 | 271.5 kb | Distal (>10kb) Multiome | 744 | |
| chr6:27,870,957–27,872,527 | 264.6 kb | Distal (>10kb) Multiome | 426 | |
| chr6:27,872,808–27,873,995 | 263.2 kb | Distal (>10kb) Multiome | 372 | |
| chr6:27,889,436–27,895,972 | 243.6 kb | Distal (>10kb) Multiome | 1215 | |
| chr6:27,902,800–27,903,766 | 233.8 kb | Distal (>10kb) Multiome | 891 | |
| chr6:28,079,998–28,081,441 | 56.7 kb | Distal (>10kb) Multiome | 1054 | |
| chr6:28,104,510–28,105,291 | 32.0 kb | Distal (>10kb) Multiome | 927 | |
| chr6:28,136,684–28,137,470 | 197 bp | At TSS Multiome | 1035 | |
| chr6:28,141,479–28,142,195 | 5.0 kb | Proximal (<10kb) Multiome | 1010 | |
| chr6:28,171,036–28,171,660 | 34.6 kb | Distal (>10kb) Multiome | 67 | |
| chr6:28,225,159–28,225,667 | 88.5 kb | Distal (>10kb) Multiome | 914 | |
| chr6:28,281,346–28,282,033 | 144.7 kb | Distal (>10kb) Multiome | 751 | |
| chr6:28,335,073–28,336,704 | 198.9 kb | Distal (>10kb) Multiome | 1036 | |
| chr6:28,349,817–28,350,289 | 213.2 kb | Distal (>10kb) Multiome | 884 | |
| chr6:28,356,177–28,356,613 | 219.5 kb | Distal (>10kb) Multiome | 569 | |
| chr6:28,383,266–28,383,869 | 246.7 kb | Distal (>10kb) Multiome | 821 | |
| chr6:28,399,292–28,400,183 | 263.0 kb | Distal (>10kb) Multiome | 978 |
Genomic view of the ZSCAN16-AS1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.