chr5 : 171,857,641 – 171,858,115

474 bp 83 TFs 1 linked gene

This 474 bp open chromatin element is linked to FBXW11 and is bound by 83 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
FBXW11		149.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

AFF4 1 dataset

ChIP HeLa_EGF GSE40632.AFF4.HeLa_EGF 147 bp overlap

ATF4 1 dataset

ChIP K562 ENCFF674KTF 112 bp overlap

Ahr::Arnt 1 dataset

Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap

BCL6 1 dataset

Motif DE_72h DE_72h-BCL6_MA0463.3 13 bp overlap

BRD4 1 dataset

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 60 bp overlap

CEBPG 1 dataset

ChIP K-562 ENCSR620VIC.CEBPG.K-562 69 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 290 bp overlap

CTCF 5 datasets

ChIP A-549 ENCSR000DPF.CTCF.A-549 50 bp overlap

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 84 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 116 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 474 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 138 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 89 bp overlap

ChIP BLaER1 ENCFF274GAT 249 bp overlap

Crx 1 dataset

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 350 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 108 bp overlap

EBF1 1 dataset

Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap

EOMES 2 datasets

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 258 bp overlap

ESR1 6 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 346 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 289 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 240 bp overlap

ChIP MCF-7_DHT GSE99626.ESR1.MCF-7_DHT 348 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 355 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 361 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 240 bp overlap

ETV4 1 dataset

ChIP T-47D GSE129803.ETV4.T-47D 162 bp overlap

EZH2 1 dataset

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 170 bp overlap

Ebf4 1 dataset

Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 280 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 284 bp overlap

ChIP DE DE-GATA4-2 426 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 342 bp overlap

ChIP DE DE-GATA6-2 423 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 273 bp overlap

ChIP foregut GSE117136.GATA6.foregut 274 bp overlap

GSC 1 dataset

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 264 bp overlap

MGA 1 dataset

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 243 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 151 bp overlap

NEUROG2 1 dataset

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 107 bp overlap

OTX1 1 dataset

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 276 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 358 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 288 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

RAD21 1 dataset

ChIP H1 ENCFF698EWO 241 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 278 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 200 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 115 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 179 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 474 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 474 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 215 bp overlap

SMARCA4 2 datasets

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 356 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 334 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 256 bp overlap

SMARCC1 2 datasets

ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 203 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 242 bp overlap

SMC1 1 dataset

ChIP DKO GSE131606.SMC1.DKO 208 bp overlap

SOX14 1 dataset

Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 333 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 474 bp overlap

SOX18 1 dataset

Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap

SOX2 3 datasets

ChIP H9 GSE46837.SOX2.H9 212 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 271 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 251 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 353 bp overlap

SOX8 1 dataset

Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

Stat5a 1 dataset

Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 190 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 353 bp overlap

TBR1 1 dataset

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 99 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 271 bp overlap

Tbx6 1 dataset

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 219 bp overlap

ZNF135 1 dataset

Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap

ZNF143 1 dataset

ChIP MCF-7 GSE76454.ZNF143.MCF-7 158 bp overlap

ZNF257 1 dataset

Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap

ZNF460 1 dataset

Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap

ZNF76 1 dataset

Motif DE_48h DE_48h-ZNF76_MA1716.2 17 bp overlap

Zfx 1 dataset

Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap

Zic2 1 dataset

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap